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The map label for this gene is fabH [H]

Identifier: 161869298

GI number: 161869298

Start: 312140

End: 313102

Strand: Reverse

Name: fabH [H]

Synonym: NMCC_0303

Alternate gene names: 161869298

Gene position: 313102-312140 (Counterclockwise)

Preceding gene: 161869299

Following gene: 161869297

Centisome position: 14.54

GC content: 56.39

Gene sequence:

>963_bases
ATGCAGTATGCCAAAATTTCCGGCACGGGCAGCTATCTTCCCGCCAACCGCGTCAGCAATGACGACCTTGCCCAAAAAGT
GGATACCTCGGACGAGTGGATTACCGCGCGCACGGGCATCAAATTCCGCCATATTGCAGCCGAAAATGAGAAAACCAGCG
ATCTTGCCGCCGAAGCAGCCCGCCGCGCACTGGATGCAGCCGGATTAGACAGCGGCGAAATCGATTTAATTATTGTGGCG
ACGGCAACGCCGGATATGCAGTTTCCTTCTACCGCCACCATCGTCCAACAAAAACTGGGCATCACCAACGGCTGCCCCGC
GTTTGACGTACAGGCGGTGTGTGCGGGCTTTATGTACGCGCTGACCACGGCAAACGCCTACATCAAAAGCGGCATGGCAA
AAAACGCGCTGGTCATCGGCGCGGAAACTTTCAGCCGCATCGTCGATTGGAACGACCGCACAACCTGCGTATTGTTCGGC
GACGGCGCGGGCGCGGTGGTTTTGAGCGCGGCGGACAAACCGGGCATCATCCACAGCAAACTCAAAGCCGACGGCAATTA
TCTGAAACTCTTAAACGTCCCCGGGCAAATCGCCTGCGGCAAAGTTTCCGGTTCGCCGTACATTTCGATGGACGGTCCCG
GCGTGTTCAAGTTTGCCGTCAAAATGCTGTCCAAAATCGCCGATGACGTTATCGAAGAAGCCGGTTATACCGCCGCTCAA
ATCGACTGGATCGTGCCGCATCAGGCAAACCGCCGCATTATCGAATCGACCGCGAAACATTTAGGTTTGAGTATGGACAA
AGTCGTCCTGACCGTCCAAGACCACGGCAACACATCCGCCGCATCGATTCCGCTGGCTTTGGATACGGGCATCCGCAGCG
GACAAATCAAACGCGGTCAAAACCTGCTGCTCGAAGGCATCGGCGGCGGTTTCGCGTGGGGCGCGGTATTGCTGCAATAT
TGA

Upstream 100 bases:

>100_bases
TCCCTGTTTCCGTCATTTGCACCCTGTCCGTATTGGGCAATCATCGGTTTTTCGCTTACAATAGCCGAATCTGAACCAAC
TATCCAAAAAGGCCGTTCCC

Downstream 100 bases:

>100_bases
ATACCATGCCGTCTGAAACAGGTTTTCAGACGGCATTTCCCATATCATGAAGCGGCAGGCTTTCTTCAAACTGATGGCGT
GTGCGGCATTTCTGTCTGCC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALDAAGLDSGEIDLIIVA
TATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFG
DGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQ
IDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY

Sequences:

>Translated_320_residues
MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALDAAGLDSGEIDLIIVA
TATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFG
DGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQ
IDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY
>Mature_320_residues
MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALDAAGLDSGEIDLIIVA
TATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFG
DGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQ
IDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=318, Percent_Identity=52.8301886792453, Blast_Score=334, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33819; Mature: 33819

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAA
CCEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHH
RRALDAAGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYA
HHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSAADKPGIIHSK
HHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEEHH
LKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQ
HCCCCCEEEEEECCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
IDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQ
EEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCC
NLLLEGIGGGFAWGAVLLQY
EEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure
MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAA
CCEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHH
RRALDAAGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYA
HHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSAADKPGIIHSK
HHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCEEEHH
LKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAAQ
HCCCCCEEEEEECCCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEE
IDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDTGIRSGQIKRGQ
EEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCC
NLLLEGIGGGFAWGAVLLQY
EEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA