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The map label for this gene is coaD

Identifier: 161869183

GI number: 161869183

Start: 181071

End: 181583

Strand: Direct

Name: coaD

Synonym: NMCC_0180

Alternate gene names: 161869183

Gene position: 181071-181583 (Clockwise)

Preceding gene: 161869182

Following gene: 161869184

Centisome position: 8.41

GC content: 52.83

Gene sequence:

>513_bases
ATGTTACCGAATACACCGCGCCGCGCCGTTTATGCCGGCAGTTTCGATCCGCCCACATTGGGGCATCTGTGGATGATACG
GCAGGCGCAATCTATGTTTGACGAACTCATCGTCGCCATCGGCATTAACCCCGACAAACGCAGCACCTATACCGTCGCTG
AAAGGCAGGATATGTTGTGCGATATTACTAAAATGTTTCCCAACGTCAGAACCGATGTATTTGAAAACCGATTTCTGGTG
CATTACGCCCGTGAGGTAGATGCAGGATTCATCGTGCGCGGCATCCGTTCTGCTTCGGATTACGAATACGAACGTTCCAT
GCGCCATATCAACAGCGACCTCGCCCCCGAAATATCCACCGTATTCCTCATGCCGCCGCGCGAAATCGCCGAAGTGTCGT
CCACTATGGTCAAAGGCTTGGTCGGGCCGGAAGGCTGGACGGAAACGATCCACCGCTACGTGCCGCAAGCTGTGTACGAA
AAAATCCTTGCCGAACATCAACACGAAAATTGA

Upstream 100 bases:

>100_bases
ATGCCGTCTGAAAATGCTTCAGACGGCATTTTACTTTGGGCATACAATACGGATGCACACGCACCAACACACAGCCGACT
ATGAAGCCGGGAGGAATCAA

Downstream 100 bases:

>100_bases
ACCCTTCTATTTTTGCAAGGCATATATGGATATGTTGGAAATTTTGTTCCGCCATCAAGACTTCGTCGCCATCAACAAAC
CGGGCGGCATATCCGTCCAC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLV
HYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYE
KILAEHQHEN

Sequences:

>Translated_170_residues
MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLV
HYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYE
KILAEHQHEN
>Mature_170_residues
MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLV
HYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYE
KILAEHQHEN

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=34.5911949685535, Blast_Score=115, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_NEIM0 (A9M0K2)

Other databases:

- EMBL:   CP000381
- RefSeq:   YP_001598349.1
- ProteinModelPortal:   A9M0K2
- EnsemblBacteria:   EBNEIT00000011374
- GeneID:   5795566
- GenomeReviews:   CP000381_GR
- KEGG:   nmn:NMCC_0180
- GeneTree:   EBGT00050000021413
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   NMEN374833:NMCC_0180-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19544; Mature: 19544

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLC
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
DITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEIST
HHHHHCCHHHHHHHHCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEE
VFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYEKILAEHQHEN
EEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINPDKRSTYTVAERQDMLC
CCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
DITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYEYERSMRHINSDLAPEIST
HHHHHCCHHHHHHHHCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEE
VFLMPPREIAEVSSTMVKGLVGPEGWTETIHRYVPQAVYEKILAEHQHEN
EEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA