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The map label for this gene is nlaB [H]

Identifier: 161869169

GI number: 161869169

Start: 166670

End: 167305

Strand: Reverse

Name: nlaB [H]

Synonym: NMCC_0164

Alternate gene names: 161869169

Gene position: 167305-166670 (Counterclockwise)

Preceding gene: 161869170

Following gene: 161869168

Centisome position: 7.77

GC content: 56.6

Gene sequence:

>636_bases
ATGGCGCGGGTCTGGGTCAAAATCCTCAACCTCTCGCTCAAACACATCGTCGGGCTCAAATACCGCATCATCGGCGCGGA
AAACATCCCCGACCGCCCCGCCGTCATCTGCGCCAAACACCAAAGCGGCTGGGAAACGCTCGCCCTTCAGGACATTTTTC
CGCCGCAGGTTTACGTTGCCAAACGCGAGTTGTTCAAAATCCCCTTTTTCGGCTGGGGCTTGAAACTGGTCAAAACCATA
GGCATAGACCGCAACAACCGCCGCGAAGCCAACGAGCAGCTCATAAAACAGGGGTTGGCGCGCAAAAACGAAGGCTATTG
GATTACCATTTTCCCCGAAGGCACGCGCCTTGCACCCGGAAAGCGCGGCAAATACAAACTCGGCGGCGCGCGCATGGCGA
AAATGTTTGAGATGGACATCGTCCCCGTCGCCCTCAACAGCGGCGAATTTTGGCCGAAAAACTCCTTTCTGAAATATCCG
GGGGAAATCACCGTCGTCATCTGTCCGACCATCCCGCACGCAAGCGGCAGCGAAGCCGAATTGATGGGAAAATGCGAACA
CCTCATCGAAACGCAGCAGCCGCTCATTTCCGGCGCAGGCCCGTTTGCCGCCAAAATGCCGTCTGAAACCGCATGA

Upstream 100 bases:

>100_bases
CATCCGCAACCTGATTTACTGGCTGATACTCTGTTCCACCCTGATTTTCCTCTTTCCCTTTATGCTGCTCGCCTCGCCTT
TCCGAGACGGGGCGCACAAG

Downstream 100 bases:

>100_bases
CCGCCTTTGTCCACACCCTTTCAGACGGCATGGAACTGACCGTCGAAATCAAGCGCCGTGCCAAGAAAAACCTGATTATC
CGCCCCGCCGGCACACATAC

Product: 1-acyl-SN-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MARVWVKILNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVAKRELFKIPFFGWGLKLVKTI
GIDRNNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPGKRGKYKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYP
GEITVVICPTIPHASGSEAELMGKCEHLIETQQPLISGAGPFAAKMPSETA

Sequences:

>Translated_211_residues
MARVWVKILNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVAKRELFKIPFFGWGLKLVKTI
GIDRNNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPGKRGKYKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYP
GEITVVICPTIPHASGSEAELMGKCEHLIETQQPLISGAGPFAAKMPSETA
>Mature_210_residues
ARVWVKILNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVAKRELFKIPFFGWGLKLVKTIG
IDRNNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPGKRGKYKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYPG
EITVVICPTIPHASGSEAELMGKCEHLIETQQPLISGAGPFAAKMPSETA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=172, Percent_Identity=28.4883720930233, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI15100175, Length=172, Percent_Identity=28.4883720930233, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=151, Percent_Identity=33.112582781457, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364648, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582856, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582854, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 23570; Mature: 23439

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVWVKILNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVA
CHHHEEHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCEEEECCCCCCHHEEE
KRELFKIPFFGWGLKLVKTIGIDRNNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPG
HHHHEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCC
KRGKYKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYPGEITVVICPTIPHASGSEAE
CCCCEEECHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCEEEEEEECCCCCCCCCHHH
LMGKCEHLIETQQPLISGAGPFAAKMPSETA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARVWVKILNLSLKHIVGLKYRIIGAENIPDRPAVICAKHQSGWETLALQDIFPPQVYVA
HHHEEHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEEECCCCCCEEEECCCCCCHHEEE
KRELFKIPFFGWGLKLVKTIGIDRNNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPG
HHHHEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCC
KRGKYKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYPGEITVVICPTIPHASGSEAE
CCCCEEECHHHHHHHHHCCEEEEEECCCCCCCCCCCEECCCEEEEEEECCCCCCCCCHHH
LMGKCEHLIETQQPLISGAGPFAAKMPSETA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]