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The map label for this gene is yhcS [C]

Identifier: 161526297

GI number: 161526297

Start: 3417028

End: 3418077

Strand: Reverse

Name: yhcS [C]

Synonym: Bmul_3128

Alternate gene names: 161526297

Gene position: 3418077-3417028 (Counterclockwise)

Preceding gene: 161526299

Following gene: 161526293

Centisome position: 99.12

GC content: 66.76

Gene sequence:

>1050_bases
ATGGATCATTTGCAGTCGATGCGCGTGTTCGTCAAGGTTGCGGATCTCGGCAGTTTCGCGCGGGCCGCGAGTGCAATGGA
TATCTCGAACGCGGTCGCGACGCGCCATGTCGCCGATCTCGAAGGCCGGCTCGGCACGCGGCTGCTGAATCGCACGACGC
GCAGCCTTTCGCTGACGGAATCGGGGCAGGTCTATCTGGAGCGTGCGCGCCAGATTCTGGACGAGCTCGAGGACGTCGAG
CAGATGGTCGTCGCGCGCAATCACGAGCCGGTCGGCACGCTGCGCATCGTCGCGCCCGTCGTGTTCGGCCTGCATAACCT
CGCACCGGTGCTGCAGTCGTACACCGAACAGTTCCCGAAAGTGGTGCCCGATCTGACGCTCGTCGATCGGCAGGTCGATC
TCGTCGAGGAAGGCTTCGACGTCGGCATCGTCGTCACGCGACAGATGCGCAGTGCGAGCATCGTCACGCGGCGTCTGACC
ACGGGCTGCATGACGGTATGCGCGACGCCGAGCTATCTGGAAAAGCACGGCGTGCCGACGCATCCGGAGCAGCTCGCCGA
GCATCCGAGCCTGAGTCTGCCGACCGAATACTGGGGCGACGAGCGCGTGTTTACGGGGCCCGACGGCGAAGTGCGCGTGC
GTCCGACCAACGTGATCGTCGCGAACAACACCGCGATGCTGCGGCAGTTCGCGCTGCTCGGAATGGGCGTCGCGATCCTG
CCGAGCTACCTGATCGGCGGCGACATCGCGCGCGGTGCGCTCGTGCGGCTGCTGCCCGATTTCAAGCTGCCGCAGGTCGA
GATCAACATCGCCTATCCGAGCCGGCGCCATCTGCCGGCGAAGGTGCGTACGTTCATCGATCACCTCGTCGAGTACTTCA
GCAAGTCGACCGACGCGACGATGGGCGAGCAGTGGGCCGCGCAGGGCGCGACGCTCCCGCCGATCGGCGTCGAAGCGCGT
GCGGAGCAGCCGGAACCGGCAGACCCGAACCTGTCGCCGCGGCTGCCGCGCGCAGGCCGTCAGCGCGTCTCGGCGCCGTC
GCCGCTCTAA

Upstream 100 bases:

>100_bases
TCGCGGACGCGCTAGGCAACTCTGCATCTTTTCCGCTGTCGTAGGAGAATTACGCATTTGCTTCAACTTTTTGAAGTTGT
AACAGCGGCAGGAGTCGTTT

Downstream 100 bases:

>100_bases
CGGCGACGCGCGGGCGCCCGAACGGGCGAGCCAAAAAGAAAACGCGGATCGAGCGATCGATCCGCGTTTTTTGTTTGCCC
GACGAAGCCGGCGGGCCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTEQFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEQLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGGDIARGALVRLLPDFKLPQVEINIAYPSRRHLPAKVRTFIDHLVEYFSKSTDATMGEQWAAQGATLPPIGVEAR
AEQPEPADPNLSPRLPRAGRQRVSAPSPL

Sequences:

>Translated_349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTEQFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEQLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGGDIARGALVRLLPDFKLPQVEINIAYPSRRHLPAKVRTFIDHLVEYFSKSTDATMGEQWAAQGATLPPIGVEAR
AEQPEPADPNLSPRLPRAGRQRVSAPSPL
>Mature_349_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTEQFPKVVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLT
TGCMTVCATPSYLEKHGVPTHPEQLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
PSYLIGGDIARGALVRLLPDFKLPQVEINIAYPSRRHLPAKVRTFIDHLVEYFSKSTDATMGEQWAAQGATLPPIGVEAR
AEQPEPADPNLSPRLPRAGRQRVSAPSPL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=33.2179930795848, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=31.5789473684211, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=28.476821192053, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=28.476821192053, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=26.962457337884, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=29.3103448275862, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789173, Length=252, Percent_Identity=29.3650793650794, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790011, Length=302, Percent_Identity=23.1788079470199, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787879, Length=264, Percent_Identity=28.030303030303, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788297, Length=143, Percent_Identity=29.3706293706294, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=189, Percent_Identity=26.4550264550265, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=25.4752851711027, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38388; Mature: 38388

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTEQFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLTTGCMTVCATPSYLEKHGVPT
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPEQLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
CHHHHHCCCCCCCCHHHCCCCEEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGGDIARGALVRLLPDFKLPQVEINIAYPSRRHLPAKVRTFIDHLVEYFSKSTDAT
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCH
MGEQWAAQGATLPPIGVEARAEQPEPADPNLSPRLPRAGRQRVSAPSPL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQSYTEQFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVPDLTLVDRQVDLVEEGFDVGIVVTRQMRSASIVTRRLTTGCMTVCATPSYLEKHGVPT
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HPEQLAEHPSLSLPTEYWGDERVFTGPDGEVRVRPTNVIVANNTAMLRQFALLGMGVAIL
CHHHHHCCCCCCCCHHHCCCCEEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGGDIARGALVRLLPDFKLPQVEINIAYPSRRHLPAKVRTFIDHLVEYFSKSTDAT
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCH
MGEQWAAQGATLPPIGVEARAEQPEPADPNLSPRLPRAGRQRVSAPSPL
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]