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The map label for this gene is yahK [H]

Identifier: 161526270

GI number: 161526270

Start: 3386409

End: 3387461

Strand: Direct

Name: yahK [H]

Synonym: Bmul_3101

Alternate gene names: 161526270

Gene position: 3386409-3387461 (Clockwise)

Preceding gene: 161526268

Following gene: 161526276

Centisome position: 98.2

GC content: 65.62

Gene sequence:

>1053_bases
ATGAGCACCACCTATGCCTACGCGGCGACCGACGCGCAATCGCCGCTCGCCCCGTTCGAATTTCAGCGCCGCGCGCTGCG
CGACCTCGACGTGCAGATCGAGATCCTCTACTGCGGCGTCTGCCATTCCGACCTCCATCAGGCGCGCAACGAATGGCGCA
ACACGATCTATCCGGTCGTGCCGGGCCACGAGATCGTCGGGCGGGTAACCGCAACCGGGCCGCAGGTCTCGCGCTTCAAG
GTCGGCGAGCTGGTCGGCGTCGGCTGTCTCGTCGATTCGTGCCGCACCTGCGCGAGCTGCGCGGAAGGCCTCGAGCAGTA
TTGCGAGAACGGCTTCGTCGGCACCTACAACGGCCAGGATCGCGTGACGGGCGACATCACGTACGGCGGCTATTCGACGC
AGATCGTCGTCGACGAAGCGTTCGTGCTGCGCGTACCCGACACGCTCGACGCGGCCGGCGCCGCGCCGCTGCTTTGCGCG
GGGATCACCACGTATTCGCCGCTGCGTCAGTGGAACGTCGGGCCCGGCAAGAAGGTCGGCATCGTCGGCCTCGGCGGGCT
CGGCCACATGGGCGTGAAGCTCGCGCGCGCGATGGGCGCGCACGTCGTGCTGTTCACGACGTCGCCGTCGAAGATCGAGG
ACGGCAAGCGGCTCGGCGCGCATGAAGTCGTCGTGTCGAAGGACGAAGCGCAGATGAACGCGCACCTGAACAGCTTCGAC
TTCATCCTGAACACGGTCGCCGCGCAGCACGACCTGAATCCGTTCCTGCATCTGCTCAAGCGCGACGGCACGATGACGCT
CGTCGGCGCGCCCGAGCACGATCACCCGTCGCCGCAGGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTCGCCGGCTCGC
TGATCGGCGGGATCGCGGAGACGCAGGAAATGCTCGACTTCTGCGCGCAGCACGGCATCACGTCCGATATCGAAATCATT
CCGATGCAGCAGATCAACGCCGCGTACGAGCGGATGCTGAAGAGCGACGTGAAGTACCGGTTCGTGATCGACATGGCGTC
GATCAAGCAGTAA

Upstream 100 bases:

>100_bases
GCCGCGCTCCTTACGATGGGGACCTGTCTCGCCGCGTCGCCACACCGCGCGGCGTGCCGTCCGTTTTGCCGGATGTTTAA
CCGGACAAGGAGCCTTACGC

Downstream 100 bases:

>100_bases
GCCGCGCCGCCGAAACGAGACGGGCCGCATGTGCGACATGCGGCCCGTTTTTCGTTGCTACGATGCGGCGCGATCGAGCG
CGCGCCGCACGGCGCGAGCC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCASCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQIVVDEAFVLRVPDTLDAAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVVSKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAQHGITSDIEII
PMQQINAAYERMLKSDVKYRFVIDMASIKQ

Sequences:

>Translated_350_residues
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFK
VGELVGVGCLVDSCRTCASCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQIVVDEAFVLRVPDTLDAAGAAPLLCA
GITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVVSKDEAQMNAHLNSFD
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAQHGITSDIEII
PMQQINAAYERMLKSDVKYRFVIDMASIKQ
>Mature_349_residues
STTYAYAATDAQSPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWRNTIYPVVPGHEIVGRVTATGPQVSRFKV
GELVGVGCLVDSCRTCASCAEGLEQYCENGFVGTYNGQDRVTGDITYGGYSTQIVVDEAFVLRVPDTLDAAGAAPLLCAG
ITTYSPLRQWNVGPGKKVGIVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVVSKDEAQMNAHLNSFDF
ILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAETQEMLDFCAQHGITSDIEIIP
MQQINAAYERMLKSDVKYRFVIDMASIKQ

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI262073058, Length=367, Percent_Identity=23.433242506812, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI71743840, Length=367, Percent_Identity=23.433242506812, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4501933, Length=366, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI34577061, Length=371, Percent_Identity=24.2587601078167, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4501929, Length=367, Percent_Identity=23.9782016348774, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI71565152, Length=317, Percent_Identity=22.397476340694, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786518, Length=340, Percent_Identity=65, Blast_Score=416, Evalue=1e-118,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=35.6521739130435, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=26.3803680981595, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI226510992, Length=315, Percent_Identity=27.3015873015873, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788073, Length=257, Percent_Identity=26.8482490272374, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788407, Length=273, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790045, Length=267, Percent_Identity=27.7153558052434, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082125, Length=198, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=336, Percent_Identity=26.1904761904762, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17562584, Length=339, Percent_Identity=27.1386430678466, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=27.8409090909091, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25146526, Length=327, Percent_Identity=25.3822629969419, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=37.7643504531722, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6319949, Length=346, Percent_Identity=34.393063583815, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323961, Length=324, Percent_Identity=32.7160493827161, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6319621, Length=324, Percent_Identity=30.8641975308642, Blast_Score=153, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6324486, Length=324, Percent_Identity=31.4814814814815, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323729, Length=324, Percent_Identity=29.9382716049383, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=345, Percent_Identity=25.2173913043478, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=381, Percent_Identity=26.246719160105, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17737895, Length=375, Percent_Identity=24, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38167; Mature: 38036

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAATDAQSPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWRNTIYPVV
CCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCASCAEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQIVVDEAFVLRVPDTLDAAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVVSKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAQHGITSDIEIIPMQQINAAYERMLKSDVKYRFVIDMASIKQ
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEEHHHHCC
>Mature Secondary Structure 
STTYAYAATDAQSPLAPFEFQRRALRDLDVQIEILYCGVCHSDLHQARNEWRNTIYPVV
CCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHHHCEECCC
PGHEIVGRVTATGPQVSRFKVGELVGVGCLVDSCRTCASCAEGLEQYCENGFVGTYNGQD
CCHHHHEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITYGGYSTQIVVDEAFVLRVPDTLDAAGAAPLLCAGITTYSPLRQWNVGPGKKVG
CEEEEEEECCEEEEEEEECEEEEECCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCCCEEE
IVGLGGLGHMGVKLARAMGAHVVLFTTSPSKIEDGKRLGAHEVVVSKDEAQMNAHLNSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHHCCCHHH
FILNTVAAQHDLNPFLHLLKRDGTMTLVGAPEHDHPSPQVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHHCCHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAQHGITSDIEIIPMQQINAAYERMLKSDVKYRFVIDMASIKQ
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]