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The map label for this gene is 161526129

Identifier: 161526129

GI number: 161526129

Start: 3239809

End: 3240705

Strand: Reverse

Name: 161526129

Synonym: Bmul_2960

Alternate gene names: NA

Gene position: 3240705-3239809 (Counterclockwise)

Preceding gene: 161526131

Following gene: 161526127

Centisome position: 93.98

GC content: 68.0

Gene sequence:

>897_bases
ATGTCGTTCGACGCGTTCGCACCGTTTCGCGTGACGGTGCAGGACACCGAGATCTTCGGTGTCAAAGGAGGCGCGGGGCC
GCCGCTTCTGCTGCTGCACGGTCACCCGCAGACTCACGTGATCTGGCATCGCGTCGCCGCGACGCTCGCGAATCACTTCA
CGGTGATCGCCACCGATCTGCGCGGTTACGGCGCGTCCGGCAAGCCGCCGAGCGACGCGCAGCATGCCCCGTATTCGAAA
CGCGCGATGGCTGCCGATCAGGTGGCCGTGATGCGCCATTTCGGCTTCGCGCAATTTCACGTCTGCGCGCACGACCGCGG
CGCGCGTGTCGCGCATCGGCTCGCGCTCGATCACCCGTCGGCCGTCGAGCGCATGATGCTGCTCGATATCGCGCCGACGC
TCGCGATGTACGAGCAGACCGACCGCGCGTTCGCGACCGCCTATTTCCACTGGTTTTTCCTGATCCAGCCCGAGCCGCTG
CCCGAAACGCTGATCGAAGGCCATACCGATGCCTACATCGAGCGTGTGATGGGCAACCGGTCGGCCGGGCTCGCGCCGTT
CGCGCCGCATGCGCTCGACGCGTATCGCACGGCGCTCGCCCAGCCGGGCGCCGTACATGCGATGTGCGAGGACTATCGCG
CCTCGGCGACGATCGATCTCGAGCACGACCGTGCCGATCTCGAACGCGGCAACAAGATCGCGTGCCCGCTGCGCGTGCTG
TGGGGCGCGAACGGCGTCGTCGCGCGCTGCTTCGAGCCGCTCGACGAATGGCGGCGCGTCGCGCGCGACGTCAGCGGCCG
CGCGCTCGACTGCGGGCACTACATCCCGGAAGAAGCGCCCGTCGCGCTGATCGACGAGATGCTCGCGTTCTTCGAGGCGC
GCGAACCGGCCGTCTAA

Upstream 100 bases:

>100_bases
ACGAGTGCTCTGTCTCTATGTGTTTTGGCTGCTGCGCCGCTCTTCGCGGTGGCCGGCGCTCCTACAATAGCCGCCATAAC
GAACCTACGAGAAACAGACC

Downstream 100 bases:

>100_bases
GGCGCCGGCTCGGCTCGGCTGGGTCGACGCGCCACGCGCCGCGCGTCAGCGGCGCGACTCCTCTTCTTCGACGAGCGGCG
GCAGCCGACGCGGCACGGGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSFDAFAPFRVTVQDTEIFGVKGGAGPPLLLLHGHPQTHVIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSK
RAMAADQVAVMRHFGFAQFHVCAHDRGARVAHRLALDHPSAVERMMLLDIAPTLAMYEQTDRAFATAYFHWFFLIQPEPL
PETLIEGHTDAYIERVMGNRSAGLAPFAPHALDAYRTALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKIACPLRVL
WGANGVVARCFEPLDEWRRVARDVSGRALDCGHYIPEEAPVALIDEMLAFFEAREPAV

Sequences:

>Translated_298_residues
MSFDAFAPFRVTVQDTEIFGVKGGAGPPLLLLHGHPQTHVIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSK
RAMAADQVAVMRHFGFAQFHVCAHDRGARVAHRLALDHPSAVERMMLLDIAPTLAMYEQTDRAFATAYFHWFFLIQPEPL
PETLIEGHTDAYIERVMGNRSAGLAPFAPHALDAYRTALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKIACPLRVL
WGANGVVARCFEPLDEWRRVARDVSGRALDCGHYIPEEAPVALIDEMLAFFEAREPAV
>Mature_297_residues
SFDAFAPFRVTVQDTEIFGVKGGAGPPLLLLHGHPQTHVIWHRVAATLANHFTVIATDLRGYGASGKPPSDAQHAPYSKR
AMAADQVAVMRHFGFAQFHVCAHDRGARVAHRLALDHPSAVERMMLLDIAPTLAMYEQTDRAFATAYFHWFFLIQPEPLP
ETLIEGHTDAYIERVMGNRSAGLAPFAPHALDAYRTALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKIACPLRVLW
GANGVVARCFEPLDEWRRVARDVSGRALDCGHYIPEEAPVALIDEMLAFFEAREPAV

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=279, Percent_Identity=27.9569892473118, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI13376164, Length=279, Percent_Identity=27.9569892473118, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI218777837, Length=232, Percent_Identity=23.7068965517241, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=240, Percent_Identity=22.9166666666667, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32925; Mature: 32794

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDAFAPFRVTVQDTEIFGVKGGAGPPLLLLHGHPQTHVIWHRVAATLANHFTVIATDL
CCCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGKPPSDAQHAPYSKRAMAADQVAVMRHFGFAQFHVCAHDRGARVAHRLALDHPS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCHH
AVERMMLLDIAPTLAMYEQTDRAFATAYFHWFFLIQPEPLPETLIEGHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHCCC
SAGLAPFAPHALDAYRTALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKIACPLRVL
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCEEEE
WGANGVVARCFEPLDEWRRVARDVSGRALDCGHYIPEEAPVALIDEMLAFFEAREPAV
ECCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFDAFAPFRVTVQDTEIFGVKGGAGPPLLLLHGHPQTHVIWHRVAATLANHFTVIATDL
CCCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEEC
RGYGASGKPPSDAQHAPYSKRAMAADQVAVMRHFGFAQFHVCAHDRGARVAHRLALDHPS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCHH
AVERMMLLDIAPTLAMYEQTDRAFATAYFHWFFLIQPEPLPETLIEGHTDAYIERVMGNR
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCHHHHCCCHHHHHHHHHCCC
SAGLAPFAPHALDAYRTALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKIACPLRVL
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCHHHHHCCCEEECCEEEE
WGANGVVARCFEPLDEWRRVARDVSGRALDCGHYIPEEAPVALIDEMLAFFEAREPAV
ECCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA