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The map label for this gene is pepQ [H]

Identifier: 161526053

GI number: 161526053

Start: 3148817

End: 3150631

Strand: Reverse

Name: pepQ [H]

Synonym: Bmul_2884

Alternate gene names: 161526053

Gene position: 3150631-3148817 (Counterclockwise)

Preceding gene: 161526054

Following gene: 161526052

Centisome position: 91.36

GC content: 70.52

Gene sequence:

>1815_bases
ATGAATGCCCGTCTCCCCGAAGTCTCGCCGGTGCCGGCCCGGCTCGCGCTGCTGCGCGGCGCGATGGTCCGCGAGGATCT
GGCCGCGTATCTCGTACCGTCCGCCGATCCGCATCTGTCCGAATATCTGCCCGAGCGCTGGCAGGCCCGCCGCTGGTTGT
CCGGCTTCACGGGCTCGGTCGGCACGCTCGTCGTGACCGCCGATTTCGCGGGCCTCTGGGTCGACAGCCGCTACTGGGTG
CAGGCCGAAGCCGAGCTCGCCGGCACCGGCGTGCAGCTGATGAAGATGACGGGCGGTCAGCAGAGCGCGCCGCACGTCGA
CTGGCTCGCGCAGAACGTGCCGGCCGGTGCGACGGTCGGCGTCGACGGCGCGGTGCTCGGCGTCGCCGCCGCGCGCGCGC
TGACGGCGGCGCTCAGCGCGCGCGGGATCGCGCTGCGCACCGATCTCGACCTGCTCGACGCGATCTGGCCCGAGCGGCCG
GCACTGCCCGCCGATCCGGTGTTCGAGCACGTCGCGCCGCAGGCCGACACGACGCGCGCGAGCAAGCTCGCCGACGTGCG
GCGTGCGATGCAGGCGCAGGGCGCGCAATGGCATTTCGTGTCGACGCTCGACGATCTCGCGTGGCTGTTCAATCTGCGCG
GCGCCGACGTCAGCTTCAATCCGGTATTCGTTGCGCACGCAATGATCGGCCTCGACAGCGCGACCTTGTTCGTCGCCGAC
GGCAAGGTGTCGCCTGCGCTGGCCGCGTCGCTCGCGCAGGACGGCGTCGAGGTGCGGCCGTACGGCGACGCGCGGGCGGC
GCTCGCCGCGCTGCCGGACGGCGCGACGTTGCTGGTCGACCCGCGCCGCGTGACGTTCGGCACGCTCGAAGCCGTGCCGG
CTGGCGTGAAGCGCGTCGAGGCCGTCAACCCGTCGACGTTCGCGAAATCGCGCAAGACGCCCGCCGAGATTGCGCATGTG
CGCGTGACGATGGAGCACGACGGCGCGGCGCTCGCCGAATTCTTCGCGTGGTTCGAGCAGGCCGTGAACCGCGACACGAT
TACCGAGTTGACGATCGACGAGCAACTGACCGCCGCGCGCGCACGGCGCCCCGGCTACGTGTCGCCGAGTTTCGCGACGA
TCGCCGGCTTCAACGCGAACGGCGCGATGCCGCATTACCGCGCGACGCCTGCGTCGCATGCGACGATCGCCGGCGACGGG
CTGCTGCTCGTCGACTCGGGCGGCCAGTACCTGACGGGCACGACCGACATCACGCGCGTCGTGCCGGTCGGCACTGTCAG
CGATCTGCAGCGGCGCGATTTCACGATCGTGCTGAAGTCGATGATGGCGCTGTCGCGTGCGCGTTTCCCGCGCGGCATCC
GCTCGCCGATGCTCGACGCGATCGCGCGCGCGCCGATGTGGGCGGCCGGTCTCGACTACGGTCACGGCACCGGCCACGGC
GTCGGCTATTTCCTGAACGTGCACGAAGGTCCGCAGGTGATTTCGCACTACGCGCCGGCCGAGCCGTACACGGCGATGGA
AGAAGGGATGATCACGTCGATCGAGCCGGGCGTGTACCGCCCCGGCCAGTGGGGCGTGCGGATCGAGAACCTGGTCGTGA
ATCGCGCGGCCGGGCAGACCGAGTTCGGCGATTTCCTCGCGTTCGAGACGCTGACGCTGTGCCCGATCGACACGCGCTGC
GTGCTGATCGAGATGCTGCACGAGGAAGAGCGCGCGTGGCTGAACGCGTATCACGCGACGGTGCGCGAGCGCGTCGGCCG
GCACGTGAGCGGCGACGCGAAAGCATGGCTCGACGCACGCACGCAGCCGATCTGA

Upstream 100 bases:

>100_bases
CGAAACGCTCGAATGGCCGGTCTGTACCGGCGCCGCGTTCGTCGCCGTCGCCGTGACGGTCGCGCTCGCGGCCCGTCGAT
GAAAGCTCTCAGGTGAAATC

Downstream 100 bases:

>100_bases
CGCGGCGAACGGCACGGGCCGCGCGGCGGCCCGACGATAACGACGGCGAGGAGCGACGATGACGGATACCGCAGTGATCG
TGGTCGACATGCAGCGCGGG

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVAAARALTAALSARGIALRTDLDLLDAIWPERP
ALPADPVFEHVAPQADTTRASKLADVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVSFNPVFVAHAMIGLDSATLFVAD
GKVSPALAASLAQDGVEVRPYGDARAALAALPDGATLLVDPRRVTFGTLEAVPAGVKRVEAVNPSTFAKSRKTPAEIAHV
RVTMEHDGAALAEFFAWFEQAVNRDTITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPASHATIAGDG
LLLVDSGGQYLTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGVRIENLVVNRAAGQTEFGDFLAFETLTLCPIDTRC
VLIEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI

Sequences:

>Translated_604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVAAARALTAALSARGIALRTDLDLLDAIWPERP
ALPADPVFEHVAPQADTTRASKLADVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVSFNPVFVAHAMIGLDSATLFVAD
GKVSPALAASLAQDGVEVRPYGDARAALAALPDGATLLVDPRRVTFGTLEAVPAGVKRVEAVNPSTFAKSRKTPAEIAHV
RVTMEHDGAALAEFFAWFEQAVNRDTITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPASHATIAGDG
LLLVDSGGQYLTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGVRIENLVVNRAAGQTEFGDFLAFETLTLCPIDTRC
VLIEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI
>Mature_604_residues
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSVGTLVVTADFAGLWVDSRYWV
QAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVGVDGAVLGVAAARALTAALSARGIALRTDLDLLDAIWPERP
ALPADPVFEHVAPQADTTRASKLADVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVSFNPVFVAHAMIGLDSATLFVAD
GKVSPALAASLAQDGVEVRPYGDARAALAALPDGATLLVDPRRVTFGTLEAVPAGVKRVEAVNPSTFAKSRKTPAEIAHV
RVTMEHDGAALAEFFAWFEQAVNRDTITELTIDEQLTAARARRPGYVSPSFATIAGFNANGAMPHYRATPASHATIAGDG
LLLVDSGGQYLTGTTDITRVVPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGVRIENLVVNRAAGQTEFGDFLAFETLTLCPIDTRC
VLIEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDARTQPI

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=612, Percent_Identity=36.2745098039216, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI264681565, Length=612, Percent_Identity=34.8039215686275, Blast_Score=348, Evalue=7e-96,
Organism=Homo sapiens, GI93141226, Length=604, Percent_Identity=33.6092715231788, Blast_Score=344, Evalue=2e-94,
Organism=Escherichia coli, GI1788728, Length=179, Percent_Identity=35.7541899441341, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=591, Percent_Identity=32.8257191201354, Blast_Score=312, Evalue=4e-85,
Organism=Caenorhabditis elegans, GI25149105, Length=617, Percent_Identity=27.0664505672609, Blast_Score=227, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322999, Length=654, Percent_Identity=30.8868501529052, Blast_Score=291, Evalue=3e-79,
Organism=Drosophila melanogaster, GI17137632, Length=613, Percent_Identity=34.094616639478, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI161078230, Length=606, Percent_Identity=27.7227722772277, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI21357287, Length=606, Percent_Identity=27.7227722772277, Blast_Score=240, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 65030; Mature: 65030

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEC
VDGAVLGVAAARALTAALSARGIALRTDLDLLDAIWPERPALPADPVFEHVAPQADTTRA
CCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
SKLADVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVSFNPVFVAHAMIGLDSATLFVAD
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
GKVSPALAASLAQDGVEVRPYGDARAALAALPDGATLLVDPRRVTFGTLEAVPAGVKRVE
CCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHHHH
AVNPSTFAKSRKTPAEIAHVRVTMEHDGAALAEFFAWFEQAVNRDTITELTIDEQLTAAR
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATPASHATIAGDGLLLVDSGGQYLTGTTDITRV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEECCCCCEEE
VPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGVRIENLVVNRAAGQT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCCEEEHEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLIEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC
>Mature Secondary Structure
MNARLPEVSPVPARLALLRGAMVREDLAAYLVPSADPHLSEYLPERWQARRWLSGFTGSV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
GTLVVTADFAGLWVDSRYWVQAEAELAGTGVQLMKMTGGQQSAPHVDWLAQNVPAGATVG
EEEEEEECCCEEEECCEEEEEEECHHCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEC
VDGAVLGVAAARALTAALSARGIALRTDLDLLDAIWPERPALPADPVFEHVAPQADTTRA
CCHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHCCCCCCCCCCHHHHHHCCCCCHHHH
SKLADVRRAMQAQGAQWHFVSTLDDLAWLFNLRGADVSFNPVFVAHAMIGLDSATLFVAD
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
GKVSPALAASLAQDGVEVRPYGDARAALAALPDGATLLVDPRRVTFGTLEAVPAGVKRVE
CCCCHHHHHHHHHCCCEEECCCCHHHHHHCCCCCCEEEECCCEEEEHHHHHHHHHHHHHH
AVNPSTFAKSRKTPAEIAHVRVTMEHDGAALAEFFAWFEQAVNRDTITELTIDEQLTAAR
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHH
ARRPGYVSPSFATIAGFNANGAMPHYRATPASHATIAGDGLLLVDSGGQYLTGTTDITRV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEECCCCCEEE
VPVGTVSDLQRRDFTIVLKSMMALSRARFPRGIRSPMLDAIARAPMWAAGLDYGHGTGHG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCC
VGYFLNVHEGPQVISHYAPAEPYTAMEEGMITSIEPGVYRPGQWGVRIENLVVNRAAGQT
EEEEEEECCCHHHHHHCCCCCCCHHHHCCCEEECCCCCCCCCCCCCEEEHEEEECCCCCC
EFGDFLAFETLTLCPIDTRCVLIEMLHEEERAWLNAYHATVRERVGRHVSGDAKAWLDAR
CHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCC
TQPI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]