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The map label for this gene is mltA [H]

Identifier: 161526025

GI number: 161526025

Start: 3120756

End: 3121988

Strand: Reverse

Name: mltA [H]

Synonym: Bmul_2856

Alternate gene names: 161526025

Gene position: 3121988-3120756 (Counterclockwise)

Preceding gene: 161526026

Following gene: 161526019

Centisome position: 90.53

GC content: 69.34

Gene sequence:

>1233_bases
ATGAAAACCAGCAGGGCGAGCGCGAGAAAGGCTTCCAGCGCGAAGATGAGCATCGGATATTGGTCGAGAAAATCTGACAT
GGCGGTTTCCATCAAGAACGGACATTGTATGTGGTTTGGACGCCGGGCGGCCGGCTGGGCGGCGGCGGTCGCGACGGCGG
CGCTGCTTGCCGCATGCGGTGGCGCGCCGACGCGGCCGACCGCGCTGAAGCCGCCGACCGGCGCGGCGATCGTGCCCGGG
CAGGTCGCCGCGAAGCGGCTCACGCCGGTGGCGTGGCAGCAGGTGCCGGGCTGGCAAGACGATTCGCTGATCGGCGCGAC
GGCCGCGCTGCGGCAGAACTGCGTGCGGCTCGCGCGGCAGCCGGCGTGGCAGCGCGCGTGCGCGGCCGCCGAGCGGCTCG
ACGAACTCGACGCGAACGGCGCGCGCGCGTTTTTCGAAACGTACTTCACGCCGTTCCAGTTCGCGAACACCGACGGCACG
CTCGACGGCCTCGTGACCGGTTATTACGAGCCGTTGCTGCACGGCTCGCGCGTGCGCCGCGGCCCGTATCAATATGCGCT
GTATCGCTGGCCGGCCGGCTATCGCGCCGGCGCGCCGCTGCCTGCGCGCGCACAGCTCGAACGCTCGGGCGTACTGAACG
GCAACGAACTCGTGTGGGTCGACGACCCGATCGAGGCGTTCTTCCTGCAGGTGCAGGGCTCGGGGCGCGTGCTGCTCGAC
GACGGCTCGGTGATGCGCGTCGGCTTCGGCGGCACCAACAATCAGCCGTATCGCTCGATCGGCAAGTGGCTGCTCGATCG
CGGCGAACTGACGCCGGCGCAGGCGACGATGCAGGGCATCAAGGCGTGGGCGAAGGCGAATCCGGGCCGTGTCGACGCGC
TGCTCGACACGAACCCGCGCTTCGTCTTCTTCCGCGAGATGCCGACGAAGGAAGAAGCGCCGCACGGCGGCGCGGACGGC
CCGATCGGCGCGCTCGGCGTGCCGCTCACGCCCGAGCGTTCGATCGCCGTCGATCCGGCGTCGATTCCGCTCGGCACGCC
GGTGTTTCTGCAGACCACGCGTCCGCTGACGAACACGCCGATGAACCGGCTCGTGTTCGCCCAAGATACGGGCAGCGCGA
TCAAGGGCGGCGTGCGGGCCGACTATTTCTGGGGGCTCGGCGACGATGCGGGCGACCTCGCCGGTCGCATGAAGCAGGTC
GGCCGGATGTGGTTGCTGTTCCCGAATTCGTGA

Upstream 100 bases:

>100_bases
GGCACTGCGCACGACGCGGCGCTGCGCACGACGCGGTCAGCGCGGCTGACGGTCGTTGTTGCGGGCGTGCTTCTTTCTGC
CCGACGCGGTCCACGCGACG

Downstream 100 bases:

>100_bases
GGGTTTTCGTGTCGGTCGTCGTGACGGCCGACAGCGGCGCGTAGCCGACGCGGCGCGCGCCTGTCGGCGAAATCGTTGGG
GCGAGGCCGGACGGTTCGCG

Product: MltA domain-containing protein

Products: Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase A [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKTSRASARKASSAKMSIGYWSRKSDMAVSIKNGHCMWFGRRAAGWAAAVATAALLAACGGAPTRPTALKPPTGAAIVPG
QVAAKRLTPVAWQQVPGWQDDSLIGATAALRQNCVRLARQPAWQRACAAAERLDELDANGARAFFETYFTPFQFANTDGT
LDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGAPLPARAQLERSGVLNGNELVWVDDPIEAFFLQVQGSGRVLLD
DGSVMRVGFGGTNNQPYRSIGKWLLDRGELTPAQATMQGIKAWAKANPGRVDALLDTNPRFVFFREMPTKEEAPHGGADG
PIGALGVPLTPERSIAVDPASIPLGTPVFLQTTRPLTNTPMNRLVFAQDTGSAIKGGVRADYFWGLGDDAGDLAGRMKQV
GRMWLLFPNS

Sequences:

>Translated_410_residues
MKTSRASARKASSAKMSIGYWSRKSDMAVSIKNGHCMWFGRRAAGWAAAVATAALLAACGGAPTRPTALKPPTGAAIVPG
QVAAKRLTPVAWQQVPGWQDDSLIGATAALRQNCVRLARQPAWQRACAAAERLDELDANGARAFFETYFTPFQFANTDGT
LDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGAPLPARAQLERSGVLNGNELVWVDDPIEAFFLQVQGSGRVLLD
DGSVMRVGFGGTNNQPYRSIGKWLLDRGELTPAQATMQGIKAWAKANPGRVDALLDTNPRFVFFREMPTKEEAPHGGADG
PIGALGVPLTPERSIAVDPASIPLGTPVFLQTTRPLTNTPMNRLVFAQDTGSAIKGGVRADYFWGLGDDAGDLAGRMKQV
GRMWLLFPNS
>Mature_410_residues
MKTSRASARKASSAKMSIGYWSRKSDMAVSIKNGHCMWFGRRAAGWAAAVATAALLAACGGAPTRPTALKPPTGAAIVPG
QVAAKRLTPVAWQQVPGWQDDSLIGATAALRQNCVRLARQPAWQRACAAAERLDELDANGARAFFETYFTPFQFANTDGT
LDGLVTGYYEPLLHGSRVRRGPYQYALYRWPAGYRAGAPLPARAQLERSGVLNGNELVWVDDPIEAFFLQVQGSGRVLLD
DGSVMRVGFGGTNNQPYRSIGKWLLDRGELTPAQATMQGIKAWAKANPGRVDALLDTNPRFVFFREMPTKEEAPHGGADG
PIGALGVPLTPERSIAVDPASIPLGTPVFLQTTRPLTNTPMNRLVFAQDTGSAIKGGVRADYFWGLGDDAGDLAGRMKQV
GRMWLLFPNS

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Note=In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=264, Percent_Identity=34.0909090909091, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 44190; Mature: 44190

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSRASARKASSAKMSIGYWSRKSDMAVSIKNGHCMWFGRRAAGWAAAVATAALLAACG
CCCCCCHHHHCCCCEEEEEEECCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHC
GAPTRPTALKPPTGAAIVPGQVAAKRLTPVAWQQVPGWQDDSLIGATAALRQNCVRLARQ
CCCCCCCCCCCCCCCEECCCHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PAWQRACAAAERLDELDANGARAFFETYFTPFQFANTDGTLDGLVTGYYEPLLHGSRVRR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
GPYQYALYRWPAGYRAGAPLPARAQLERSGVLNGNELVWVDDPIEAFFLQVQGSGRVLLD
CCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEE
DGSVMRVGFGGTNNQPYRSIGKWLLDRGELTPAQATMQGIKAWAKANPGRVDALLDTNPR
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FVFFREMPTKEEAPHGGADGPIGALGVPLTPERSIAVDPASIPLGTPVFLQTTRPLTNTP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCC
MNRLVFAQDTGSAIKGGVRADYFWGLGDDAGDLAGRMKQVGRMWLLFPNS
CHHEEEEECCCHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MKTSRASARKASSAKMSIGYWSRKSDMAVSIKNGHCMWFGRRAAGWAAAVATAALLAACG
CCCCCCHHHHCCCCEEEEEEECCCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHHHHC
GAPTRPTALKPPTGAAIVPGQVAAKRLTPVAWQQVPGWQDDSLIGATAALRQNCVRLARQ
CCCCCCCCCCCCCCCEECCCHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PAWQRACAAAERLDELDANGARAFFETYFTPFQFANTDGTLDGLVTGYYEPLLHGSRVRR
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
GPYQYALYRWPAGYRAGAPLPARAQLERSGVLNGNELVWVDDPIEAFFLQVQGSGRVLLD
CCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCEEEEE
DGSVMRVGFGGTNNQPYRSIGKWLLDRGELTPAQATMQGIKAWAKANPGRVDALLDTNPR
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
FVFFREMPTKEEAPHGGADGPIGALGVPLTPERSIAVDPASIPLGTPVFLQTTRPLTNTP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCC
MNRLVFAQDTGSAIKGGVRADYFWGLGDDAGDLAGRMKQVGRMWLLFPNS
CHHEEEEECCCHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]