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The map label for this gene is paaK [H]

Identifier: 161526024

GI number: 161526024

Start: 3119250

End: 3120548

Strand: Direct

Name: paaK [H]

Synonym: Bmul_2855

Alternate gene names: 161526024

Gene position: 3119250-3120548 (Clockwise)

Preceding gene: 161526023

Following gene: 161526027

Centisome position: 90.45

GC content: 66.36

Gene sequence:

>1299_bases
ATGACTACCCCGCTACCGCTCGAGCCGATCGAGACCGCATCCCGCGACGAGCTGACCGCGCTGCAGCTCGAACGCCTCAA
ATGGTCGCTGCGGCACGCGTACGACAACTCGCCGGTCTATCGCCGCAAGTTCGACGAAGCCGGCGTGCATCCGGACGACC
TGCAAACGCTCGCCGACCTGTCGCGCTTCCCGTTCACGACGAAGAGCGACCTGCGCGACAGCTATCCGTTCGGGATGTTC
GCGGTGCCGCAGGAGCGGGTCTCGCGCATTCATGCGTCGTCGGGCACGACCGGCAAACCGACCGTGGTCGGCTACACGGC
GCGCGACATCGATACGTGGGCGAACCTCGTGGCGCGCTCGATCCGCGCGGCCGGAGCGCGCCCCGGCGACAAGGTGCACG
TGAGCTACGGGTACGGGCTGTTCACCGGCGGCCTCGGCGCGCACTACGGCGCCGAGCGCGCGGGGCTCACCGTCATTCCG
TTCGGCGGCGGCCAGACCGAAAAACAGGTGCAGCTGATCCAGGACTTCCGTCCCGACATCATCATGGTGACGCCGAGCTA
CATGCTGTCGATCGCCGACGAGTTCGAACGGCAGGGCGTCGATCCGGCGCAGAGTTCGCTGCGCATCGGCATCTTCGGCG
CCGAGCCGTGGACCAACGACATGCGCGTCGCGATCGAGCAGCGGATGAAGATCGACGCGGTCGACATCTACGGGCTGTCC
GAAGTGATGGGCCCCGGCGTCGCGTCGGAATGCGTCGAAACGAAGGACGGCCCGACGATCTGGGAAGATCACTTCTATCC
GGAAATCATCGATCCCGACACCGGCGAAGTGCTGCCGGACGGCGAACTCGGCGAGCTCGTGTTCACGTCGCTGACGAAGG
AAGCGCTGCCGATCATCCGCTACCGGACGCGCGACCTCACGCGTCTGCTGCCGGGCACCGCACGTACGATGCGACGCATG
GAAAAGATCACGGGCCGCTCGGACGACATGATGATCGTGCGCGGCGTGAACGTGTTTCCGACGCAAATCGAGGAGCAGCT
GCTGAAGCAGCGCGCGCTCGCGCCGCACTACCAGATCGTGCTGACGAAGGAAGGGCCGCTCGACGTACTGACGCTCAACG
TCGAGCCGTGCCCCGAAACGGCGCCCGACACCGCTGCGATTCAGGCCGCGAAGCAGGCGCTCGCGTACGACATCAAATCG
CTGATCGGCGTGACGGCGGTGATCGACGTGCTGCCGGTCAACGGGATCGAGCGCTCGGTGGGCAAGGCGCGCCGCGTGAT
CGACAAGCGCAAGGGCTGA

Upstream 100 bases:

>100_bases
TGGCAATGTTTCGCGGCAAGTCCGCGCAGATCAAGGGCACCGTGATACCGGAAGACCGCTGACGTCGGCGCCGCGCCCAT
AACAAACACTGGAGACACGC

Downstream 100 bases:

>100_bases
GCCGGCAAGTCGTCGCGCGCCGCATAGCGAGCGTCGCGGCGACCGCAACGCCATTTCGATGCAGCGCCCGACCGGCGAAC
GCCGGCCGGGCGTTTTTCTT

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDDLQTLADLSRFPFTTKSDLRDSYPFGMF
AVPQERVSRIHASSGTTGKPTVVGYTARDIDTWANLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEFERQGVDPAQSSLRIGIFGAEPWTNDMRVAIEQRMKIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQIEEQLLKQRALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKS
LIGVTAVIDVLPVNGIERSVGKARRVIDKRKG

Sequences:

>Translated_432_residues
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDDLQTLADLSRFPFTTKSDLRDSYPFGMF
AVPQERVSRIHASSGTTGKPTVVGYTARDIDTWANLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIP
FGGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEFERQGVDPAQSSLRIGIFGAEPWTNDMRVAIEQRMKIDAVDIYGLS
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRM
EKITGRSDDMMIVRGVNVFPTQIEEQLLKQRALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKS
LIGVTAVIDVLPVNGIERSVGKARRVIDKRKG
>Mature_431_residues
TTPLPLEPIETASRDELTALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDDLQTLADLSRFPFTTKSDLRDSYPFGMFA
VPQERVSRIHASSGTTGKPTVVGYTARDIDTWANLVARSIRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPF
GGGQTEKQVQLIQDFRPDIIMVTPSYMLSIADEFERQGVDPAQSSLRIGIFGAEPWTNDMRVAIEQRMKIDAVDIYGLSE
VMGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGELGELVFTSLTKEALPIIRYRTRDLTRLLPGTARTMRRME
KITGRSDDMMIVRGVNVFPTQIEEQLLKQRALAPHYQIVLTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSL
IGVTAVIDVLPVNGIERSVGKARRVIDKRKG

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=434, Percent_Identity=65.668202764977, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47765; Mature: 47634

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLPLEPIETASRDELTALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDDLQTLADL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKSDLRDSYPFGMFAVPQERVSRIHASSGTTGKPTVVGYTARDIDTWANLVARS
HHCCCCCHHHHCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEFERQGVDPAQSSLRIGIFGAEPWTNDMRVAIEQRMKIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQIEEQLLKQRALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSLIGVTAVIDVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRVIDKRKG
HHHHHHHHHCCC
>Mature Secondary Structure 
TTPLPLEPIETASRDELTALQLERLKWSLRHAYDNSPVYRRKFDEAGVHPDDLQTLADL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHH
SRFPFTTKSDLRDSYPFGMFAVPQERVSRIHASSGTTGKPTVVGYTARDIDTWANLVARS
HHCCCCCHHHHCCCCCCCEEECCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
IRAAGARPGDKVHVSYGYGLFTGGLGAHYGAERAGLTVIPFGGGQTEKQVQLIQDFRPDI
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCE
IMVTPSYMLSIADEFERQGVDPAQSSLRIGIFGAEPWTNDMRVAIEQRMKIDAVDIYGLS
EEECHHHHHHHHHHHHHCCCCHHHCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCHH
EVMGPGVASECVETKDGPTIWEDHFYPEIIDPDTGEVLPDGELGELVFTSLTKEALPIIR
HHHCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YRTRDLTRLLPGTARTMRRMEKITGRSDDMMIVRGVNVFPTQIEEQLLKQRALAPHYQIV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEE
LTKEGPLDVLTLNVEPCPETAPDTAAIQAAKQALAYDIKSLIGVTAVIDVLPVNGIERSV
EECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
GKARRVIDKRKG
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]