Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 161525990

GI number: 161525990

Start: 3074035

End: 3074643

Strand: Direct

Name: coaE [H]

Synonym: Bmul_2821

Alternate gene names: 161525990

Gene position: 3074035-3074643 (Clockwise)

Preceding gene: 161525989

Following gene: 161525991

Centisome position: 89.14

GC content: 67.32

Gene sequence:

>609_bases
ATGTTTTCAGTGGGACTCACCGGCGGTATCGGCAGCGGCAAGACGACCGTCGCCGATCTGTTCGCCGCGCGCGGCGCGTC
CATCGTCGATACCGACGTGATCGCGCACCGTATTACCGCGCCGGGCGGTCTCGCGATGCGCGAGATCGAGCGTACGTTCG
GGCCGGATTTCGTCGCCGCCGACGGCTCGCTCGATCGCGCGAAGATGCGCGCGATCGTCTTCAGCGATGACGCTGCGCGC
CGCCGCCTCGAGGCGATCACGCATCCGCTGATCCGCGCGGAAACCGATCGCGAAGCGCGTGAAGCGCAAGGCGCGTACGT
GATCTACGTCGTGCCGCTGCTCGTCGAATCGGGCAACTGGAAGGCGCGTGCCGACCGGATACTCGTCGTCGACTGTCCGG
TCGAGACCCAGATTGCGCGCGTGATGCGGCGCAACGATTTCACGCGCGAGCAGGTCGAAGCGATCATCGCGCGGCAGGCG
ACGCGCGAGGCGCGTCTTGCCGCGGCCGACGACGTGATCGTCAACGACGCGGCGACACCGGCAGCACTCGCCGCGCAGGT
CGATGCACTGCACCAACGCTATTTGCAGCACGCGGCAACGATGCGCTGA

Upstream 100 bases:

>100_bases
TTTCGAGGAGCCGATTCCGTTCGGCCCGTTCCTTGCGGCCGGCGGTGCGGCGACGCTGTTTTTCGGTACCCCTTTTTATT
CCGCGCTCGGAGGCTGACAC

Downstream 100 bases:

>100_bases
ACGCGGGCACTCGTGATGGCGTACGAAATTGGCGCGTTGCTAGGGTAGAGTGTGAGCATTAGAATGTCCTGCATTGTTTC
CATCCCTATCCGAGAGGCGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFSVGLTGGIGSGKTTVADLFAARGASIVDTDVIAHRITAPGGLAMREIERTFGPDFVAADGSLDRAKMRAIVFSDDAAR
RRLEAITHPLIRAETDREAREAQGAYVIYVVPLLVESGNWKARADRILVVDCPVETQIARVMRRNDFTREQVEAIIARQA
TREARLAAADDVIVNDAATPAALAAQVDALHQRYLQHAATMR

Sequences:

>Translated_202_residues
MFSVGLTGGIGSGKTTVADLFAARGASIVDTDVIAHRITAPGGLAMREIERTFGPDFVAADGSLDRAKMRAIVFSDDAAR
RRLEAITHPLIRAETDREAREAQGAYVIYVVPLLVESGNWKARADRILVVDCPVETQIARVMRRNDFTREQVEAIIARQA
TREARLAAADDVIVNDAATPAALAAQVDALHQRYLQHAATMR
>Mature_202_residues
MFSVGLTGGIGSGKTTVADLFAARGASIVDTDVIAHRITAPGGLAMREIERTFGPDFVAADGSLDRAKMRAIVFSDDAAR
RRLEAITHPLIRAETDREAREAQGAYVIYVVPLLVESGNWKARADRILVVDCPVETQIARVMRRNDFTREQVEAIIARQA
TREARLAAADDVIVNDAATPAALAAQVDALHQRYLQHAATMR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=36.734693877551, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=36.734693877551, Blast_Score=117, Evalue=8e-27,
Organism=Homo sapiens, GI110227607, Length=192, Percent_Identity=27.0833333333333, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI110227605, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI110227603, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI110227601, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI205277394, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=50, Blast_Score=181, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17554944, Length=182, Percent_Identity=31.8681318681319, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=205, Percent_Identity=32.6829268292683, Blast_Score=86, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=28.1081081081081, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24658602, Length=163, Percent_Identity=30.0613496932515, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21936; Mature: 21936

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVGLTGGIGSGKTTVADLFAARGASIVDTDVIAHRITAPGGLAMREIERTFGPDFVAA
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEC
DGSLDRAKMRAIVFSDDAARRRLEAITHPLIRAETDREAREAQGAYVIYVVPLLVESGNW
CCCCCHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEEEHCCCCC
KARADRILVVDCPVETQIARVMRRNDFTREQVEAIIARQATREARLAAADDVIVNDAATP
EECCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
AALAAQVDALHQRYLQHAATMR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSVGLTGGIGSGKTTVADLFAARGASIVDTDVIAHRITAPGGLAMREIERTFGPDFVAA
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEC
DGSLDRAKMRAIVFSDDAARRRLEAITHPLIRAETDREAREAQGAYVIYVVPLLVESGNW
CCCCCHHHEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEEEEEHCCCCC
KARADRILVVDCPVETQIARVMRRNDFTREQVEAIIARQATREARLAAADDVIVNDAATP
EECCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
AALAAQVDALHQRYLQHAATMR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA