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The map label for this gene is ffh [H]

Identifier: 161525962

GI number: 161525962

Start: 3046662

End: 3048029

Strand: Direct

Name: ffh [H]

Synonym: Bmul_2793

Alternate gene names: 161525962

Gene position: 3046662-3048029 (Clockwise)

Preceding gene: 161525954

Following gene: 161525963

Centisome position: 88.35

GC content: 66.23

Gene sequence:

>1368_bases
ATGCTCGACAATCTCACTCAACGGATGGCGCGCGTCGTCAAGACGCTGCGCGGCGAAGCCCGGCTCACCGAGGCGAATAC
GCAGGAAATGCTCCGCGAAGTGCGTCTCGCGCTGCTCGAGGCCGACGTCGCGCTGCCGGTCGTCCGCGAATTCATCGCGA
AGGTGAAGGAAAAGGCGCTCGGCGAGGAAGTCATCAGCAGCCTGTCGCCGGGCCAGGCGCTCGTCGGCGTCGTGCAGAAG
GAGCTGACCGCCGTGATCGGCGGCGACTACGAAGGCAAGGCCGCCGAGCTGAACCTCGCGGTCTCGCCGCCTGCCGTGAT
CCTGATGGCCGGCCTGCAGGGCGCCGGCAAGACGACGACGGCCGGCAAGCTCGCGAAACTGCTGCGCGAGAAGTACAAGA
AGAAGGTGCTGACCGTGTCGTGCGACGTCTATCGCCCGGCCGCGATCATGCAGCTGAAAACGGTGAGCGAACAGGTCGGC
GCCGACTTCTTCCCGTCCACGCCCGACCAGAAGCCGGTCGACATCGCGGTTGCGGCCGTCGACTGGGCGAAGCGCCACTA
CCACGACGTGCTGATCGTCGATACGGCCGGCCGGCTCGGTATCGACGAAGCGATGATGCAGGAAATCGCCGCGCTGCACG
GCGTGCTGAAACCGGCGGAAACGCTGTTCGTCGTCGACGCGATGCTCGGCCAGGATGCCGTCAACACCGCGAAGGCGTTC
AACGACACGCTGCCGCTCACGGGCGTCGTGCTGACCAAGCTCGACGGCGACTCGCGCGGCGGCGCCGCGCTGTCGGTGCG
GCACGTGACGGGCAAGCCGATCAAGTTCGTCGGCGTCGCCGAGAAGCTCGACGGCCTCGAGGTGTTCCACCCCGACCGGA
TGGCCAACCGGATCCTCGGCATGGGCGACATCCTCGCGCTCGTCGAGGAAGCGCAGCGCGGCGTCGACGTGCAGGCCGCG
CAGAAGCTCGCCGACAAGGTGAAGAAAGGCGGCGACTTCGACCTGAACGATTTCCGCGCGCAGATCTCGCAGATGAAGAA
CATGGGCGGGCTGTCGTCGCTGATGGACAAACTCCCCGCGCAGTTCCAGCAGGCCGCGGCCGGCGCCGACATGGGCCAGG
CCGAGAAGCAGATCCGGCGGATGGAAGGGATCATCAACTCGATGACGCCGGCCGAGCGCGCGAAACCCGAAATCATCAAG
GCGACGCGCAAGCGCCGCATTGCAGCCGGCGCGGGCGTGCCGGTGCAGGAAGTCAACCGGATGCTGAACCAGTACGATCA
GATGCGTACGATGATGAAGAAGCTGAAGGGCGGCAACATGCAGAAGATGATGCGCGGCCTGAAGGGCATGATGCCCGGCC
TGCGCTGA

Upstream 100 bases:

>100_bases
ACAATATCCATGTTCGAAGTTTACACTAGGCCCCCTTCCCGCGACGGCTCCGTTGTTCGATGACCGCCGCGCCTTCGGGC
CCCACTGTCCATCGCTCCCC

Downstream 100 bases:

>100_bases
TTCCGTCCGCCGGCCGGCGCGCGGGTTTTTGCCGTAGCGCGCACCGGCCGTTGTGCTTCACTCTTATTTGTATACCGACT
GTCCGCCAGAACACATGAAC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVSPPAVILMAGLQGAGKTTTAGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVSEQVG
ADFFPSTPDQKPVDIAVAAVDWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGVLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKQIRRMEGIINSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR

Sequences:

>Translated_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVSPPAVILMAGLQGAGKTTTAGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVSEQVG
ADFFPSTPDQKPVDIAVAAVDWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGVLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKQIRRMEGIINSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
>Mature_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAAELNLAVSPPAVILMAGLQGAGKTTTAGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVSEQVG
ADFFPSTPDQKPVDIAVAAVDWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGVLKPAETLFVVDAMLGQDAVNTAKAF
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKQIRRMEGIINSMTPAERAKPEIIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=458, Percent_Identity=30.3493449781659, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI226371618, Length=349, Percent_Identity=31.8051575931232, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI89061728, Length=165, Percent_Identity=33.9393939393939, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI23308697, Length=202, Percent_Identity=32.6732673267327, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI295424842, Length=202, Percent_Identity=32.6732673267327, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788963, Length=452, Percent_Identity=64.6017699115044, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1789874, Length=279, Percent_Identity=34.4086021505376, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=461, Percent_Identity=29.0672451193059, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI193206261, Length=202, Percent_Identity=34.6534653465347, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325345, Length=428, Percent_Identity=31.3084112149533, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17647949, Length=445, Percent_Identity=30.1123595505618, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24641198, Length=271, Percent_Identity=28.7822878228782, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49230; Mature: 49230

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAAELNLAVSPPAVILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHEECCCCCCCCCH
AGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVSEQVGADFFPSTPDQKPVDIAVAAV
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
DWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGVLKPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHH
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILG
CCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGQAEKQIRRMEGIINSMTPAERAKPEIIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAAELNLAVSPPAVILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHEECCCCCCCCCH
AGKLAKLLREKYKKKVLTVSCDVYRPAAIMQLKTVSEQVGADFFPSTPDQKPVDIAVAAV
HHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
DWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGVLKPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHH
NDTLPLTGVVLTKLDGDSRGGAALSVRHVTGKPIKFVGVAEKLDGLEVFHPDRMANRILG
CCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGQAEKQIRRMEGIINSMTPAERAKPEIIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]