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The map label for this gene is nrdB [H]

Identifier: 161525957

GI number: 161525957

Start: 3039755

End: 3040945

Strand: Reverse

Name: nrdB [H]

Synonym: Bmul_2788

Alternate gene names: 161525957

Gene position: 3040945-3039755 (Counterclockwise)

Preceding gene: 161525958

Following gene: 161525956

Centisome position: 88.18

GC content: 60.96

Gene sequence:

>1191_bases
ATGACCGCCGTAACTCCCGCGAGCGGAGCGCAGCAAAACGCGATGCGCACCTCCGCGGGGATGGCTGTCGGAATGCAGGC
TGCGTCGCCTGCCGCCCATCAGGTCCGTGACATTTTCGAAGGCGATCTTGCGGTGCCGCCGCAAGCATCGGCTGTTCCCG
CCGGCGGTTCCGAAGCGCGGGTCAATGTCGCCGACAAGCGCATCATCAACGGCCAGACTGACGTCAATCAGCTGGTGCCG
TTCAAGTACAAGTGGGCGTGGGAGAAGTATCTGGCCGGTTGCGCGAACCACTGGATGCCGCAGGAAATCAACATGTCCCG
CGACATCGCGCTGTGGAAGGATCCGAACGGGCTGACCGAAGACGAGCGCCGCATCGTCAAGCGCAACCTCGGCTTCTTCG
TCACGGCCGACTCGCTCGCCGCGAACAACATCGTGCTCGGCACGTACCGCCACATCACCGCACCGGAGTGCCGCCAGTTC
CTGCTGCGCCAGGCATTCGAAGAGGCGATCCACACGCACGCGTATCAATACATCGTCGAGTCGCTCGGGCTCGACGAAGG
CGAGATCTTCAACGCGTACCACGAAGTCCCGTCGATCCGCGCGAAAGACGAATTCCTGATCCCGTTCATCCATACGCTGA
CGGACCCGGCCTTCAAGACCGGCACGCTCGAAGCGGATCAGAAGCTGCTGAAGTCGCTGATCGTGTTCGCCTGCATCATG
GAAGGCCTGTTCTTCTATGTCGGGTTCACGCAGATCCTCGCGCTCGGCCGCCAGAACAAGATGACGGGTGCTGCGGAGCA
ATATCAGTACATCCTGCGCGACGAGTCGATGCACTGCAATTTCGGCATCGACCTGATCAACCAGATCAAGCTCGAAAACC
CGCACCTGTGGACGGCCGAGTTCCGTGCGGAGATCCGCGAGCTGTTCAAGCAGGCTGTCGAACTCGAATACCGCTACGCC
GAGGACACGATGCCGCGCGGCGTGCTGGGCCTGAACGCGTCGATGTTCAAGAGCTATCTGCGCTTCATCTGCAACCGTCG
TTGCCAGCAGATCGGCCTCGATCCGCTGTTCCCGAACGAGGAAAACCCGTTCCCGTGGATGAGCGAGATGATCGACCTGA
AGAAGGAACGCAACTTCTTCGAGACGCGTGTGATCGAGTATCAGACGGGAGGCGCGCTGTCCTGGGAGTAA

Upstream 100 bases:

>100_bases
AAAGGATTTTTCGTGAGCGAACCCTTTTATCGCTCAGGAAAAGATGGTACAAACCGTTCTAAATTGATGGTGAGAATTTA
TGCTCAACTGGGATGACGAG

Downstream 100 bases:

>100_bases
CCCGCAGCAGCGAACCCGTCACATGATGGAGCAGCCGGCGGCCTCTCGGCGCCGGCCCAAGGTTTAGGAGCAAGAACGCC
TGATGCAAAGCATGCCCGGT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTAVTPASGAQQNAMRTSAGMAVGMQAASPAAHQVRDIFEGDLAVPPQASAVPAGGSEARVNVADKRIINGQTDVNQLVP
FKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQF
LLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVPSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIM
EGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAEFRAEIRELFKQAVELEYRYA
EDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLFPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE

Sequences:

>Translated_396_residues
MTAVTPASGAQQNAMRTSAGMAVGMQAASPAAHQVRDIFEGDLAVPPQASAVPAGGSEARVNVADKRIINGQTDVNQLVP
FKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQF
LLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVPSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIM
EGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAEFRAEIRELFKQAVELEYRYA
EDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLFPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
>Mature_395_residues
TAVTPASGAQQNAMRTSAGMAVGMQAASPAAHQVRDIFEGDLAVPPQASAVPAGGSEARVNVADKRIINGQTDVNQLVPF
KYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFL
LRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVPSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIME
GLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAEFRAEIRELFKQAVELEYRYAE
DTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLFPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI289177074, Length=358, Percent_Identity=27.0949720670391, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4557845, Length=403, Percent_Identity=26.302729528536, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI260064013, Length=403, Percent_Identity=26.302729528536, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI42544136, Length=322, Percent_Identity=28.2608695652174, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI289177076, Length=298, Percent_Identity=28.5234899328859, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1788567, Length=293, Percent_Identity=26.2798634812287, Blast_Score=101, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17551968, Length=389, Percent_Identity=25.9640102827763, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193206379, Length=304, Percent_Identity=22.3684210526316, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17567153, Length=227, Percent_Identity=27.7533039647577, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322434, Length=330, Percent_Identity=31.5151515151515, Blast_Score=159, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6321619, Length=320, Percent_Identity=23.4375, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18079279, Length=320, Percent_Identity=27.8125, Blast_Score=145, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 45023; Mature: 44892

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVTPASGAQQNAMRTSAGMAVGMQAASPAAHQVRDIFEGDLAVPPQASAVPAGGSEAR
CCCCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
VNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTE
EEHHHHHEECCCCCHHHHCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCH
DERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVE
HHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGLDEGEIFNAYHEVPSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIM
HHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCCEEHHH
FRAEIRELFKQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLFPNE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
CCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC
>Mature Secondary Structure 
TAVTPASGAQQNAMRTSAGMAVGMQAASPAAHQVRDIFEGDLAVPPQASAVPAGGSEAR
CCCCCCCCCHHHHHHHHCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCE
VNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTE
EEHHHHHEECCCCCHHHHCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCH
DERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVE
HHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGLDEGEIFNAYHEVPSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIM
HHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
EGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEECCCCCEEHHH
FRAEIRELFKQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFICNRRCQQIGLDPLFPNE
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
CCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]