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The map label for this gene is aroE [H]

Identifier: 161525941

GI number: 161525941

Start: 3024992

End: 3025858

Strand: Reverse

Name: aroE [H]

Synonym: Bmul_2772

Alternate gene names: 161525941

Gene position: 3025858-3024992 (Counterclockwise)

Preceding gene: 161525942

Following gene: 161525940

Centisome position: 87.75

GC content: 73.82

Gene sequence:

>867_bases
GTGAGCGCGACCGCCCCGACGCGCGGTGCCGACCGCTACGTGGTATTCGGCAATCCGGTGGCGCACAGCAAGTCGCCGTT
CATCCACGCGCAGTTCGCCGCGCAGACGGGCGAGGCGATCGACTATACGCACCGGCTCGCGCCGGTCGACGGCTTCGAGG
CGGCCGTGCGCGCCTTCATCGCCGAAGGCGGACGCGGCGCGAACGTGACCGTGCCGTTCAAGCTCGACGCGCATGCGCTT
GCCGACACGCTGTCGCCGCGGGCGGCGGCGGCCGGCGCCGTCAATACGCTGCGTTTCGACGCAGACGGCCGCATCTACGG
CGACAACACGGACGGCGTCGGCCTCGTGCGCGACATCGAGTCGAACCTCGGCGTGTCGCTCGCGGGCGCGCGCATCCTGC
TGCTCGGCGCGGGCGGCGCGGCGCGCGGCGTGGTGCTGCCGATGCTGGACCGGGCGCCGCTGTCGATCACGATCGTGAAC
CGCACGGCGAGCAAGGCCGAAGCGCTGGTCAGCCAGTTCATGCAGGCTGCGCACGACGCGGGCTGCACGCTCGCGGGCGG
CGGCCCCGGCGAAGTGCGCGCGCAGCCGTACGACGTGATCGTCAACGCGACGGCCGGCAGCCTCGACGCGGCGCTGCCCG
AGTGCGACGCGGCCGCGTTCGGCGCCGGCACGCTCGCCTACGACATGATGTACGGCGCACAGCCGACCGTGTTCATGCAG
CACGCGTCGTCGCTCGGCGCGCGCACCGCGGACGGGCTCGGCATGCTCGTCGAGCAGGCCGCCGAATCGTTCTTCGTGTG
GCGCGGCGTGCGCCCCGACGGCGCGCCGGTGCTGGCCGCGCTGCGCCGCGCGCTCGCGGCGAACTGA

Upstream 100 bases:

>100_bases
AAGCCTCCGCGCAGACCGAGGCCGAAGCGCTGGCCGAATCGGACGACGGTGCGCCGGGCGCCGATGCCGACGCAGGCGCG
TCGCAGCAGGAGCGCGCATC

Downstream 100 bases:

>100_bases
ACGGCGCGAGCGGCACGTGGTAGCGGTGACCGGTACGCAACGCACGCGCGTGGTCAGCCCGACGCGCTGGATCGTCTACG
CGGGCGCGGTGTTCGCGGCC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSATAPTRGADRYVVFGNPVAHSKSPFIHAQFAAQTGEAIDYTHRLAPVDGFEAAVRAFIAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLDRAPLSITIVN
RTASKAEALVSQFMQAAHDAGCTLAGGGPGEVRAQPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HASSLGARTADGLGMLVEQAAESFFVWRGVRPDGAPVLAALRRALAAN

Sequences:

>Translated_288_residues
MSATAPTRGADRYVVFGNPVAHSKSPFIHAQFAAQTGEAIDYTHRLAPVDGFEAAVRAFIAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLDRAPLSITIVN
RTASKAEALVSQFMQAAHDAGCTLAGGGPGEVRAQPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HASSLGARTADGLGMLVEQAAESFFVWRGVRPDGAPVLAALRRALAAN
>Mature_287_residues
SATAPTRGADRYVVFGNPVAHSKSPFIHAQFAAQTGEAIDYTHRLAPVDGFEAAVRAFIAEGGRGANVTVPFKLDAHALA
DTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIESNLGVSLAGARILLLGAGGAARGVVLPMLDRAPLSITIVNR
TASKAEALVSQFMQAAHDAGCTLAGGGPGEVRAQPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQH
ASSLGARTADGLGMLVEQAAESFFVWRGVRPDGAPVLAALRRALAAN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=47.1223021582734, Blast_Score=237, Evalue=7e-64,
Organism=Escherichia coli, GI1787983, Length=259, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=169, Percent_Identity=33.7278106508876, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29505; Mature: 29373

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAPTRGADRYVVFGNPVAHSKSPFIHAQFAAQTGEAIDYTHRLAPVDGFEAAVRAFI
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEHEEHH
SNLGVSLAGARILLLGAGGAARGVVLPMLDRAPLSITIVNRTASKAEALVSQFMQAAHDA
HCCCEEECCCEEEEEECCCCCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPGEVRAQPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHCCHHHHHHHHHCCCCHHHHH
HASSLGARTADGLGMLVEQAAESFFVWRGVRPDGAPVLAALRRALAAN
HHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SATAPTRGADRYVVFGNPVAHSKSPFIHAQFAAQTGEAIDYTHRLAPVDGFEAAVRAFI
CCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRFDADGRIYGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEHEEHH
SNLGVSLAGARILLLGAGGAARGVVLPMLDRAPLSITIVNRTASKAEALVSQFMQAAHDA
HCCCEEECCCEEEEEECCCCCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPGEVRAQPYDVIVNATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHCCHHHHHHHHHCCCCHHHHH
HASSLGARTADGLGMLVEQAAESFFVWRGVRPDGAPVLAALRRALAAN
HHHHCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA