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The map label for this gene is maeB [H]

Identifier: 161525923

GI number: 161525923

Start: 3005456

End: 3007798

Strand: Reverse

Name: maeB [H]

Synonym: Bmul_2754

Alternate gene names: 161525923

Gene position: 3007798-3005456 (Counterclockwise)

Preceding gene: 161525927

Following gene: 161525922

Centisome position: 87.22

GC content: 65.56

Gene sequence:

>2343_bases
ATGCCGTCGAACAGTCATTCTAATCCGCACGTCACGAGACACATGTCCACCCAAGCCTCCTCCAAAGCCAAGCTCCGCGA
AGCCGCCCTCGACTACCACGAATTCCCGACGCCGGGCAAAGTCGCCATCGCCCCGACCAAGCAGATGATCAACCAGCGCG
ACCTTGCGCTCGCGTATTCGCCGGGCGTTGCGTTCGCATGCGAGGAGATCGTCGAGAATCCGCTGAATGCCGCGCGCTTC
ACCGCGCGCAGCAACCTCGTCGGCGTCGTCACCAACGGTACCGCGGTGCTCGGGCTCGGCAACATCGGCCCGCTCGCGTC
GAAGCCGGTGATGGAAGGCAAGGCCGTGCTGTTCAAGAAGTTCGCCGGCATCGACGTGTTCGACATCGAGCTGAACGAGT
CCGATCCGCACAAGCTGGTCGACGTGATCGCCGCGCTCGAGCCGACCTTCGGCGGCATCAACCTCGAGGACATCAAGGCG
CCCGACTGCTTCATCGTCGAGCGCGAAGCGCGCAAGCGCATGAAGATTCCGGTGTTCCACGACGACCAGCACGGCACCGC
GATCGTCGTGGCCGCCGCCGTCACGAACGGGCTGAAGGTCGTCGGCAAGGACATCAAGAAGGTCAAGCTCGTCGCGTCGG
GCGCCGGCGCCGCCGCACTCGCGTGTCTCGATCTGCTCGTCGACATCGGCCTGCCGATCGAGAACATCACGGTGACCGAC
CTTGCCGGCGTCGTCTACAAGGGCCGTACCGAGCTGATGGATCCGGACAAGGAGCGCTTCGCGCGCGAAACCGACGCGCG
CACGCTCGCCGAAGTGATCGACGGCGCGGACATCTTCCTCGGCCTGTCGGCTGCCGGCGTGCTGAAGCAGGAGATGGTGA
AGGGGATGGCCGAGCGCCCGCTGATTCTCGCGCTCGCGAACCCGACGCCGGAAATCCTGCCGGAAGTCGCGCTCGAAGTG
CGCCCCGACGCGGTGCTCGCGACGGGCCGCACCGACTATCCGAACCAGGTCAACAACGTGCTCTGCTTCCCGTTCATCTT
CCGCGGCGCGCTCGACGTCGGCGCGACGACGATCACGCGGGAAATGGAGATCGCGGCCGTCAACGCGATCGCGGAACTCG
CGCAGCAGGAGCAGAGCGACATCGTCGCGACCGCGTACGGGATCCAGGATCTGTCGTTCGGGCCCGAATACCTGATTCCG
AAGCCGTTCGATCCGCGCCTGATCGTGAAGATCGCGCCGGCCGTCGCGCAGGCCGCGATGGACGGCGGCGTCGCGACGCG
TCCGATCGAGGACATGGAAGCGTACAAGCAGCATCTGCAGCAGTTCGTCTATCACAGCGGTACGACGATGAAGCCGATCT
TCCAGATCGCGCGTGCGGCGCCGGAAGAGAAGAAGCGCGTCGTGTTCGCGGAAGGCGAAGAAGAGCGCGTGTTGCGTGCC
GTTCAGATCATCGTCGACGAAAAACTGGCGAAGCCGATCCTGATCGGCCGCCCGGCCGTGATCGAACACCGCATCCAGCG
CTACGGCCTGCGTCTGACGCCGGGCACCGACTTCACGGTCGTGAACACCGAGCACGACGAGCGCTACCGCGACTTCTGGC
AGACGTACTACAAGATGATGGCGCGCAAGGGCATCAGCGAACAGCTCGCGCGCGTCGAAATGCGCCGCCGCACGACGCTG
ATCGGCTCGATGCTCGTGAAGAAGGGCGAGGCGGACGGGATGATCTGCGGCACGATCAGCACGACGCACCGTCATCTGCA
CTTCATCGACCAGGTGATCGGCAAGCGGCCCGGCTGCAGCGTCTACGCGGCGATGAACGGCCTCGTGCTGCCCGGCCGCC
AGATCTTCCTCGTCGATACGCACGTGAACGTCGACCCGACGCCCGAGCAGCTCGCCGAGATCACGATCATGGCCGCGGAA
GAAGTGCGCCGCTTCGGCATCGAGCCGAAGGTCGCGCTGCTGTCGCACTCGAACTTCGGCACGAGCAACGCGCCGTCCGC
ACAGAAGATGCGCGATACGCTCGCGATCCTGAAGGAACGTGCGCCGGACCTGACGGTCGACGGCGAAATGCACGGCGATG
TGGCGCTCGACGCGGCGCTGCGCAAGGAAATCCTGCCGGAATCGACGCTCGAAGGCGACGCGAACCTGCTGGTGCTGCCG
AACATCGACGCAGCGAACATCGCGTACAACCTGCTGAAGACGGCGGCCGGCAACAACATCGCGATCGGCCCGATCCTGCT
CGGCGCCGCGCAGCCGGTGCACGTGCTGACCGAATCGGCGACCGTGCGCCGGATCGTGAACATGGCGGCGCTGCTCGTCG
CCGATGTGAACGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
GTACGGGGCGAACGGCAGCGGTTCCTGCACCGTTCAGTACATTTTTGTCGCGGCTGTTGCACCCGAATCGACGGTCAGAG
GGCGGTCGATTGGCGCTACA

Downstream 100 bases:

>100_bases
GCGCACACGCGCGGTGCCGGGCAGACCGGTGCCGCGCGGCAGGCGAAAACGTCAACAATCGAAAAAAAGGCGTGCCCGCA
ACGGGCACGCCGCCGGGCAT

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 780; Mature: 779

Protein sequence:

>780_residues
MPSNSHSNPHVTRHMSTQASSKAKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARF
TARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKA
PDCFIVEREARKRMKIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENITVTD
LAGVVYKGRTELMDPDKERFARETDARTLAEVIDGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVALEV
RPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPEYLIP
KPFDPRLIVKIAPAVAQAAMDGGVATRPIEDMEAYKQHLQQFVYHSGTTMKPIFQIARAAPEEKKRVVFAEGEEERVLRA
VQIIVDEKLAKPILIGRPAVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMARKGISEQLARVEMRRRTTL
IGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEQLAEITIMAAE
EVRRFGIEPKVALLSHSNFGTSNAPSAQKMRDTLAILKERAPDLTVDGEMHGDVALDAALRKEILPESTLEGDANLLVLP
NIDAANIAYNLLKTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR

Sequences:

>Translated_780_residues
MPSNSHSNPHVTRHMSTQASSKAKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARF
TARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKA
PDCFIVEREARKRMKIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENITVTD
LAGVVYKGRTELMDPDKERFARETDARTLAEVIDGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVALEV
RPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPEYLIP
KPFDPRLIVKIAPAVAQAAMDGGVATRPIEDMEAYKQHLQQFVYHSGTTMKPIFQIARAAPEEKKRVVFAEGEEERVLRA
VQIIVDEKLAKPILIGRPAVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMARKGISEQLARVEMRRRTTL
IGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEQLAEITIMAAE
EVRRFGIEPKVALLSHSNFGTSNAPSAQKMRDTLAILKERAPDLTVDGEMHGDVALDAALRKEILPESTLEGDANLLVLP
NIDAANIAYNLLKTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
>Mature_779_residues
PSNSHSNPHVTRHMSTQASSKAKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFT
ARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKKFAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAP
DCFIVEREARKRMKIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENITVTDL
AGVVYKGRTELMDPDKERFARETDARTLAEVIDGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVALEVR
PDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPEYLIPK
PFDPRLIVKIAPAVAQAAMDGGVATRPIEDMEAYKQHLQQFVYHSGTTMKPIFQIARAAPEEKKRVVFAEGEEERVLRAV
QIIVDEKLAKPILIGRPAVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMMARKGISEQLARVEMRRRTTLI
GSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCSVYAAMNGLVLPGRQIFLVDTHVNVDPTPEQLAEITIMAAEE
VRRFGIEPKVALLSHSNFGTSNAPSAQKMRDTLAILKERAPDLTVDGEMHGDVALDAALRKEILPESTLEGDANLLVLPN
IDAANIAYNLLKTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI62420882, Length=352, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI62420880, Length=352, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI239049447, Length=352, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI4505143, Length=343, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI4505145, Length=368, Percent_Identity=26.9021739130435, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI270265879, Length=368, Percent_Identity=27.7173913043478, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1788806, Length=753, Percent_Identity=61.7529880478088, Blast_Score=968, Evalue=0.0,
Organism=Escherichia coli, GI1788635, Length=322, Percent_Identity=33.2298136645963, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788800, Length=315, Percent_Identity=32.0634920634921, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17537199, Length=474, Percent_Identity=25.5274261603376, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356279, Length=476, Percent_Identity=26.0504201680672, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362672, Length=476, Percent_Identity=26.0504201680672, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362674, Length=476, Percent_Identity=26.0504201680672, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78707242, Length=408, Percent_Identity=25.9803921568627, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78707238, Length=408, Percent_Identity=25.9803921568627, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78707240, Length=349, Percent_Identity=26.3610315186246, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646386, Length=350, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646388, Length=350, Percent_Identity=27.1428571428571, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 84618; Mature: 84487

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNSHSNPHVTRHMSTQASSKAKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEEC
PGVAFACEEIVENPLNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKK
CCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHH
FAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRMKIPVFH
HCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHCCCCCCEEE
DDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENITVTD
CCCCCCEEEEEEHHHCCHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEHHH
LAGVVYKGRTELMDPDKERFARETDARTLAEVIDGADIFLGLSAAGVLKQEMVKGMAERP
HHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCC
LILALANPTPEILPEVALEVRPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITR
EEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHH
EMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIAPAVAQAAM
HHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHH
DGGVATRPIEDMEAYKQHLQQFVYHSGTTMKPIFQIARAAPEEKKRVVFAEGEEERVLRA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCEEEEECCCHHHHHHH
VQIIVDEKLAKPILIGRPAVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMM
HHHHHHHHHCCCEEECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHH
ARKGISEQLARVEMRRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCS
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCE
VYAAMNGLVLPGRQIFLVDTHVNVDPTPEQLAEITIMAAEEVRRFGIEPKVALLSHSNFG
EEEECCCEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
TSNAPSAQKMRDTLAILKERAPDLTVDGEMHGDVALDAALRKEILPESTLEGDANLLVLP
CCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEC
NIDAANIAYNLLKTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
CCCHHHHHHHHHHHCCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PSNSHSNPHVTRHMSTQASSKAKLREAALDYHEFPTPGKVAIAPTKQMINQRDLALAYS
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEEC
PGVAFACEEIVENPLNAARFTARSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAVLFKK
CCHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCCCCCCCHHHHHHH
FAGIDVFDIELNESDPHKLVDVIAALEPTFGGINLEDIKAPDCFIVEREARKRMKIPVFH
HCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHCCCCCCEEE
DDQHGTAIVVAAAVTNGLKVVGKDIKKVKLVASGAGAAALACLDLLVDIGLPIENITVTD
CCCCCCEEEEEEHHHCCHHHHCCCHHEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEHHH
LAGVVYKGRTELMDPDKERFARETDARTLAEVIDGADIFLGLSAAGVLKQEMVKGMAERP
HHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCC
LILALANPTPEILPEVALEVRPDAVLATGRTDYPNQVNNVLCFPFIFRGALDVGATTITR
EEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHH
EMEIAAVNAIAELAQQEQSDIVATAYGIQDLSFGPEYLIPKPFDPRLIVKIAPAVAQAAM
HHHHHHHHHHHHHHHHHHCCEEEEEECCEECCCCCCCCCCCCCCCEEEEEECHHHHHHHH
DGGVATRPIEDMEAYKQHLQQFVYHSGTTMKPIFQIARAAPEEKKRVVFAEGEEERVLRA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHCEEEEECCCHHHHHHH
VQIIVDEKLAKPILIGRPAVIEHRIQRYGLRLTPGTDFTVVNTEHDERYRDFWQTYYKMM
HHHHHHHHHCCCEEECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHH
ARKGISEQLARVEMRRRTTLIGSMLVKKGEADGMICGTISTTHRHLHFIDQVIGKRPGCS
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCE
VYAAMNGLVLPGRQIFLVDTHVNVDPTPEQLAEITIMAAEEVRRFGIEPKVALLSHSNFG
EEEECCCEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
TSNAPSAQKMRDTLAILKERAPDLTVDGEMHGDVALDAALRKEILPESTLEGDANLLVLP
CCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEC
NIDAANIAYNLLKTAAGNNIAIGPILLGAAQPVHVLTESATVRRIVNMAALLVADVNAAR
CCCHHHHHHHHHHHCCCCCEEECCEEECCCCCHHHHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]