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The map label for this gene is tkt1 [H]

Identifier: 161525917

GI number: 161525917

Start: 2999530

End: 3001602

Strand: Reverse

Name: tkt1 [H]

Synonym: Bmul_2748

Alternate gene names: 161525917

Gene position: 3001602-2999530 (Counterclockwise)

Preceding gene: 161525921

Following gene: 161525916

Centisome position: 87.04

GC content: 66.86

Gene sequence:

>2073_bases
ATGCCGCCGTGCTCCCGTTTTCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCCACCACCCTGAT
GGCCAACGCGATCCGTGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGTCACCCGGGCATGCCGATGGGCATGG
CCGAAATCGGCGTGGCGCTCTGGTCGCGCCACCTGAAGCACAACCCGACGAACCCGCACTGGGCGGATCGCGACCGTTTC
GTGCTGTCGAACGGTCACGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACCGGCTACGACCTGCCGATCGAAGAGCT
GAAGAACTTCCGCCAGCTGCACTCGAAGACGCCGGGCCACCCCGAATACGGCATCACGCCGGGCGTCGAGACGACCACCG
GCCCGCTCGGCCAGGGTCTCGCGAACGCGGTCGGCATGGCGCTCGGCGAAGCGCTGATGGCCGACGAGTTCAACCGTCCG
GACGCGAAGATCGTCGATCACTACACGTACGTGTTCCTCGGCGACGGCTGCCTGATGGAAGGCATCTCGCACGAGGCCTG
CTCGCTCGCCGGCACGCTGAAGCTGAACAAGCTGATCGCGCTGTACGACGACAACGGCATCTCGATCGACGGCGACGTCG
TCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAAGCGTACGGCTGGAACGTGATCGCGAACGTGAACGGCCATGAC
GTCGATGCGGTCGACGCGGCGATCGCCAAGGCGAAGCAGTCGGACAAGCCGACGCTGATCTGCTGCAAGACGGTGATCGG
CAAGGGCGCGGCGACGAAGGCGGGCGGCCATGACGTGCACGGCGCGGCGCTCGGCGCGGAAGAAATCGCGAAGACGCGCG
AAGCGCTCGGCTGGAAGTGGGAGCCGTTCGTGATTCCGCAGGAAGTCTATGCGGCATGGGACGCGAAGGAAGCCGGCAAG
CGTGCCGAAGCGGCGTGGAACGACGCGTTCGCGCAGTATCGCGCGAAGTATCCGCAGGAAGCGGCCGAATTCGAGCGCCG
CATGGCGAACCAGCTGCCGGCCGACTGGGCCGAGAAGGCAAAGGCGATCGTCGCGGGCGCGAACGAGCGCGCCGAGACGG
TGGCGACGCGCAAGGCATCGCAGCAGGCGATCGAAGGGCTGGCCGCGGTGTTGCCGGAGCTGCTCGGCGGCTCGGCCGAC
CTGACCGGTTCGAACCTGACGAACTGGAAGGCCTCGAAGGCCGTGCGCGCGAATCCGGAAGGCGCGGGCGTGCTGCTCGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAACGGCCTCGCGCTGCACGGCGGCCACAAGC
CGTTCGGCGGCACGTTCCTGACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTGGCTGCGCTGATGAAGGTGCCGTCG
ATCTTCGTGTTCACGCACGACTCGATCGGCCTCGGCGAAGACGGCCCGACGCACCAGTCGGTCGAGCACGTGTCGAGCCT
GCGCCTGATTCCGCACCTCGACGTGTGGCGTCCGGCCGATACGGTCGAAACCGCCGTCGCGTGGACGCATGCGGTCGCGG
CCCACCGTCCGTCGGCGCTGATCTTCAGCCGCCAGAACCTCGCGTTCAATCCGCGCACCGACGCGCAGATCGCGAACATC
GAGAAGGGCGGCTACGTGCTGAAGGACTGGGACGAGGAAGTCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCCGA
GGTCGAACTCGCGATGAAGGCCGTCGAGCCGCTCGCGCAGCAAGGGATCGCCGCGCGCGTCGTGTCGATGCCGGCGACCA
CCGTGTTCGACCGCCAGGATGCCGAATACAAGGAACGCGTGCTGCCGCACGGCGTGCGTCGCGTCGCGATCGAAGCGGGC
GTGACCGATTTCTGGCGCAAGTACGTCGGCCTCGAAGGCGGCGTCGTCGGGATCGACACGTTCGGCGAATCGGCACCGGC
CGGCGTGCTGTTCAAGTATTTCGGCTTCACCGTCGACCACGTCGTCGACACCGTGAAGGCCGTGCTCGCCTAA

Upstream 100 bases:

>100_bases
AAAATGACGAGCTTTGCAGCCCCGTCCGTAGGCTCCGTCCGCTTCGCGTCCGTCAGGCGCCGCACTGCGCGCCGGGAACG
GTCGATGCGCGAGCTTCCGG

Downstream 100 bases:

>100_bases
GCAATCAAAACATTCGCGACGCGCGCCGCCCCTCGCGCGCGTCGCACGTGAAGCTGCACGAAACGAATTTTTTCAGCCAT
CAGGAGATAGACCATGACGA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPCSRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRP
DAKIVDHYTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIANVNGHD
VDAVDAAIAKAKQSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAEAAWNDAFAQYRAKYPQEAAEFERRMANQLPADWAEKAKAIVAGANERAETVATRKASQQAIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVSSLRLIPHLDVWRPADTVETAVAWTHAVAAHRPSALIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEVVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYKERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVDHVVDTVKAVLA

Sequences:

>Translated_690_residues
MPPCSRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRP
DAKIVDHYTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIANVNGHD
VDAVDAAIAKAKQSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAEAAWNDAFAQYRAKYPQEAAEFERRMANQLPADWAEKAKAIVAGANERAETVATRKASQQAIEGLAAVLPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
IFVFTHDSIGLGEDGPTHQSVEHVSSLRLIPHLDVWRPADTVETAVAWTHAVAAHRPSALIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEVVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYKERVLPHGVRRVAIEAG
VTDFWRKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVDHVVDTVKAVLA
>Mature_689_residues
PPCSRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRPD
AKIVDHYTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIANVNGHDV
DAVDAAIAKAKQSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGKR
AEAAWNDAFAQYRAKYPQEAAEFERRMANQLPADWAEKAKAIVAGANERAETVATRKASQQAIEGLAAVLPELLGGSADL
TGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPSI
FVFTHDSIGLGEDGPTHQSVEHVSSLRLIPHLDVWRPADTVETAVAWTHAVAAHRPSALIFSRQNLAFNPRTDAQIANIE
KGGYVLKDWDEEVVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYKERVLPHGVRRVAIEAGV
TDFWRKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVDHVVDTVKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=679, Percent_Identity=27.2459499263623, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI4507521, Length=679, Percent_Identity=27.2459499263623, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI133778974, Length=595, Percent_Identity=26.218487394958, Blast_Score=136, Evalue=6e-32,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=63.6363636363636, Blast_Score=874, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=60.6606606606607, Blast_Score=823, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=682, Percent_Identity=26.3929618768328, Blast_Score=160, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=673, Percent_Identity=49.3313521545319, Blast_Score=613, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6319593, Length=667, Percent_Identity=45.1274362818591, Blast_Score=548, Evalue=1e-156,
Organism=Drosophila melanogaster, GI45551847, Length=703, Percent_Identity=25.74679943101, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI45550715, Length=703, Percent_Identity=25.74679943101, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24666278, Length=587, Percent_Identity=25.8943781942078, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24645119, Length=658, Percent_Identity=25.3799392097264, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74353; Mature: 74222

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCSRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRPDAKIVDHYTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHECCEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIANVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCHHHHHCCCEEEEECCCCC
VDAVDAAIAKAKQSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAEAAWNDAFAQYRAKYPQEAAEFERRMANQLPADWAEKA
CCEECHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
KAIVAGANERAETVATRKASQQAIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVSSLRLIPHLDVWRPADTVETAVAWTHAVAAHRPSAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEVVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPATTVFDRQDAEYKERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVDHVVDTVKAVLA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
PPCSRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRPDAKIVDHYTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHECCEEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIANVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCHHHHHCCCEEEEECCCCC
VDAVDAAIAKAKQSDKPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAEAAWNDAFAQYRAKYPQEAAEFERRMANQLPADWAEKA
CCEECHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHH
KAIVAGANERAETVATRKASQQAIEGLAAVLPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAAINGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPS
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSVEHVSSLRLIPHLDVWRPADTVETAVAWTHAVAAHRPSAL
EEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEVVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPATTVFDRQDAEYKERVLPHGVRRVAIEAGVTDFWRKYVGLEGGVVGIDT
CCHHHHHHHCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVDHVVDTVKAVLA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]