| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is leuS [H]
Identifier: 161525901
GI number: 161525901
Start: 2983444
End: 2986038
Strand: Reverse
Name: leuS [H]
Synonym: Bmul_2732
Alternate gene names: 161525901
Gene position: 2986038-2983444 (Counterclockwise)
Preceding gene: 161525902
Following gene: 161525900
Centisome position: 86.59
GC content: 66.47
Gene sequence:
>2595_bases ATGCACGAGAGATACGTACCCGCCGACGTCGAAGCCGCCGCCCAGGGCGACTGGCGCGCAGCCGATGCCTACAAGACGCA GGAAGACGCGCAGAAGCCGAAGTTCTACTGCGTGTCGATGCTGCCGTATCCGTCCGGCAAGCTGCACATGGGTCACGTGC GCAACTACACGATCAACGACGTGATGTACCGCTATCTGCGGATGAACGGCTACAACGTGCTGATGCCGATGGGCTGGGAC GCGTTCGGGATGCCCGCGGAGAACGCCGCGATGGCCAACGGCGTGCCGCCCGCGAAGTGGACCTACGACAACATCGACTA CATGAAGGGCCAGATGCAGTCGATGGGCCTCGCGATCGACTGGTCGCGCGAGATCGCGACCTGCAAGCCCGACTACTACA AGTGGAACCAGTGGCTGTTCCTGAAGATGCTCGAGAAGGGCATCGCGTACAAGAAGACGGGCACCGTGAACTGGGATCCG GTCGACCAGACCGTGCTCGCGAACGAGCAGGTGATCGACGGGCGCGGCTGGCGCTCGGGTGCGCTCGTCGAGAAGCGCGA GATCCCGATGTACTACCTGCGCATCACGCAGTACGCGGACGAGCTGCTGAACGACCTCGACGGCCTCGGCTGGCCCGAGC GCGTGAAGATCATGCAGCAGAACTGGATCGGCAAGAGCTTCGGCGTGAACTTCGGCTTCCCGTACGAACTCGACGGCGAG AAGCAGCTGCTGCGCGTGTTCACGACGCGCGCTGACACGATCATGGGCGTCACGTTCTGCGCGATCGCGGCCGAGCATCC GCTCGCCACGCGCCTCGCGCAGGGCAAGCCCGAGCTGCAGGCGTTCATCGACGAATGCAAGCGCGGCGGCGTCGCCGAGG CCGACATGGCGACGATGGAGAAGAAGGGCGTCGCGACGGGCTTCTCGGTCACGCATCCGCTGACGGGCGAGCCGGTCGAG GTGTGGATCGGCAACTACGTGCTGATGAGCTACGGCGAAGGCGCCGTGATGGGCGTGCCGGGCCACGACGAACGCGACTT CGCGTTCGCGAAGAAGTACGGCCTGCCGATCAAGCAGGTGATCGCGGCCGAAGGCCATACGTACTCGCTCGACGCCTGGC AGGAGTGGTACGGCGACAAGGACATCGCGGTCTGCATCAACAGCGGCAAGTACGACGGCCTCGGCTACGCGGCGGCCGTC GATGCGGTGGCGGCCGACCTGAAGGCGGGCGGCTTCGGCGACAAGCAGGTCACGTGGCGTCTGCGCGACTGGGGCATTTC GCGCCAGCGCTACTGGGGCACGCCGATCCCGATCATCCACTGCCCGTCGTGCGGCGACGTGCCGGTGCCGGAAAAGGACC TGCCCGTCGTGCTGCCGGAAGACCTCGTGCCGGACGGCTCGGGCAACCCGCTCGCGAAGTCCGAAGCGTTCCTGAACTGC ACGTGTCCGAAGTGCGGCGCGGCCGCGAAGCGCGAAACCGACACGATGGACACCTTCGTCGATTCGTCGTGGTACTTCTC GCGCTACACGGCACCGGACGCCGAGACGATGGTCGACGCGCGCACCGACTACTGGATGCCGATGGACCAGTACATCGGCG GCATCGAGCACGCGATCCTGCACCTGCTGTATTCGCGCTTCTGGACGAAGGTGATGCGCGATCTCGGCCTCGTGAAGTTC GGCGAGCCGGCGAAGAACCTGCTCACGCAGGGCATGGTGCTGAACGAGACGTACTATCGCGAGGACGCGGCGGGCAAGAA GACCTGGTACAACCCGGCCGACGTGACCGTCACGCACGACGACAAGGGCCGCCCGGTCGGCGCGACGCTGAACGCGGACG GCCAGCCGGTCGTGCTCGGCGGCATCGAGAAGATGTCGAAGTCGAAGAACAACGGCGTCGATCCGCAGGTGCTGATCGAC CAGTACGGCGCGGATACCGCGCGCCTGTTCACGATGTTCGCCGCGCCGCCCGAGCAGCAGCTCGAGTGGTCGGGCGCCGG CGTCGAGGGCGCGAGCCGCTTCCTGCGCCGCGTGTGGAGCTTCGGCTATGCGAATCGCGAGGCGCTCGCCTCGCGCGCGG GCTTCGATGCGGCCGCGCTCGGCGACGCCGACAAGGCGCTGCGCCGCGAAATCTATAGCGTGCTGAAGCAGGCCGACTTC GACTATCAGCGTCTGCAATACAACACGGTCGTGTCGGCCGCGATGAAGATGCTGAACGCGATCGACGGTGCGAAGGGCGC GACGCCGGGCGTGCTGCGCGAAGCGTACGGCGTGCTGCTGCGCGTGCTGTATCCGGTGGTTCCGCACGTCACGTACGAGC TCTGGAAGGCGCTCGGCTATGCCGACGAATTCGGTCCGCTGCTCGACGCGCCGTGGCCGAAGGTCGACGAGGCGGCGCTC GAGCAGGCCGAGATCGAACTCGTGCTGCAGGTGAACGGCAAGGTGCGCGGCGCGCTGAAGGTCGCGAAGGACGCGAGCCG CGAGGCGATCGAAGCCGCGGCGCTCGCCGACGACGCGTTCGCGAAGTTCGGCGAAGGCAAGCCGGCGAAGAAGATCGTCG TCGTGCCGGGCCGCCTCGTGAACATCGTCGTCTGA
Upstream 100 bases:
>100_bases CCGGCACGGCCCGCCTTGTTCCTGCGCCGGGCCAGCACGATTTTCGATCCACTCCGCGCGCGAGCCGTCGCGTCGCATAA AGCCTAGTCCGAACCACACC
Downstream 100 bases:
>100_bases CGGCCGCCGGCCGTCGGGCGTACACAGAAGGAGCCAAGGTGATCCGCAGATCGTTTTTGATGCTCGTCGGCAGCGCGGTC GCGCTGTCCGCATGCGGTTT
Product: leucyl-tRNA synthetase
Products: NA
Alternate protein names: Leucine--tRNA ligase; LeuRS [H]
Number of amino acids: Translated: 864; Mature: 864
Protein sequence:
>864_residues MHERYVPADVEAAAQGDWRAADAYKTQEDAQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNVLMPMGWD AFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDP VDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGE KQLLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADMATMEKKGVATGFSVTHPLTGEPVE VWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQVIAAEGHTYSLDAWQEWYGDKDIAVCINSGKYDGLGYAAAV DAVAADLKAGGFGDKQVTWRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNC TCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKF GEPAKNLLTQGMVLNETYYREDAAGKKTWYNPADVTVTHDDKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLID QYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGYANREALASRAGFDAAALGDADKALRREIYSVLKQADF DYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLREAYGVLLRVLYPVVPHVTYELWKALGYADEFGPLLDAPWPKVDEAAL EQAEIELVLQVNGKVRGALKVAKDASREAIEAAALADDAFAKFGEGKPAKKIVVVPGRLVNIVV
Sequences:
>Translated_864_residues MHERYVPADVEAAAQGDWRAADAYKTQEDAQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNVLMPMGWD AFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDP VDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGE KQLLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADMATMEKKGVATGFSVTHPLTGEPVE VWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQVIAAEGHTYSLDAWQEWYGDKDIAVCINSGKYDGLGYAAAV DAVAADLKAGGFGDKQVTWRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNC TCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKF GEPAKNLLTQGMVLNETYYREDAAGKKTWYNPADVTVTHDDKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLID QYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGYANREALASRAGFDAAALGDADKALRREIYSVLKQADF DYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLREAYGVLLRVLYPVVPHVTYELWKALGYADEFGPLLDAPWPKVDEAAL EQAEIELVLQVNGKVRGALKVAKDASREAIEAAALADDAFAKFGEGKPAKKIVVVPGRLVNIVV >Mature_864_residues MHERYVPADVEAAAQGDWRAADAYKTQEDAQKPKFYCVSMLPYPSGKLHMGHVRNYTINDVMYRYLRMNGYNVLMPMGWD AFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAIDWSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDP VDQTVLANEQVIDGRGWRSGALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGE KQLLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADMATMEKKGVATGFSVTHPLTGEPVE VWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQVIAAEGHTYSLDAWQEWYGDKDIAVCINSGKYDGLGYAAAV DAVAADLKAGGFGDKQVTWRLRDWGISRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNC TCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAILHLLYSRFWTKVMRDLGLVKF GEPAKNLLTQGMVLNETYYREDAAGKKTWYNPADVTVTHDDKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLID QYGADTARLFTMFAAPPEQQLEWSGAGVEGASRFLRRVWSFGYANREALASRAGFDAAALGDADKALRREIYSVLKQADF DYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLREAYGVLLRVLYPVVPHVTYELWKALGYADEFGPLLDAPWPKVDEAAL EQAEIELVLQVNGKVRGALKVAKDASREAIEAAALADDAFAKFGEGKPAKKIVVVPGRLVNIVV
Specific function: Unknown
COG id: COG0495
COG function: function code J; Leucyl-tRNA synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]
Homologues:
Organism=Homo sapiens, GI7661872, Length=868, Percent_Identity=36.8663594470046, Blast_Score=540, Evalue=1e-153, Organism=Escherichia coli, GI1786861, Length=874, Percent_Identity=50.8009153318078, Blast_Score=875, Evalue=0.0, Organism=Escherichia coli, GI1790708, Length=386, Percent_Identity=23.5751295336788, Blast_Score=83, Evalue=8e-17, Organism=Caenorhabditis elegans, GI71997517, Length=792, Percent_Identity=30.9343434343434, Blast_Score=356, Evalue=3e-98, Organism=Caenorhabditis elegans, GI71997510, Length=792, Percent_Identity=30.9343434343434, Blast_Score=356, Evalue=3e-98, Organism=Caenorhabditis elegans, GI212645227, Length=338, Percent_Identity=29.585798816568, Blast_Score=139, Evalue=6e-33, Organism=Saccharomyces cerevisiae, GI6323414, Length=834, Percent_Identity=40.4076738609113, Blast_Score=565, Evalue=1e-162, Organism=Saccharomyces cerevisiae, GI6321531, Length=401, Percent_Identity=23.6907730673317, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21355409, Length=867, Percent_Identity=35.7554786620531, Blast_Score=449, Evalue=1e-126, Organism=Drosophila melanogaster, GI281366294, Length=162, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=1e-11,
Paralogues:
None
Copy number: 800 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001412 - InterPro: IPR002300 - InterPro: IPR002302 - InterPro: IPR014729 - InterPro: IPR009080 - InterPro: IPR013155 - InterPro: IPR009008 [H]
Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]
EC number: =6.1.1.4 [H]
Molecular weight: Translated: 95874; Mature: 95874
Theoretical pI: Translated: 5.27; Mature: 5.27
Prosite motif: PS00178 AA_TRNA_LIGASE_I
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MHERYVPADVEAAAQGDWRAADAYKTQEDAQKPKFYCVSMLPYPSGKLHMGHVRNYTIND CCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEEECCCCCCCHHH VMYRYLRMNGYNVLMPMGWDAFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAID HHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCEECCCHHHHHHHHHHCCEEEE WSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSG CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCCEEECCCCCCCC ALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGE CCEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCH KQLLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADMATME HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH KKGVATGFSVTHPLTGEPVEVWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQV HCCCCCCCEECCCCCCCCCEEEECCEEEEECCCCCEEECCCCCCCCHHHHHHHCCCHHHH IAAEGHTYSLDAWQEWYGDKDIAVCINSGKYDGLGYAAAVDAVAADLKAGGFGDKQVTWR HHCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE LRDWGISRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNC EHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCEECCHHCCCCCCCCCCCCCCCEEEE TCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAIL CCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHCHHHHHHH HLLYSRFWTKVMRDLGLVKFGEPAKNLLTQGMVLNETYYREDAAGKKTWYNPADVTVTHD HHHHHHHHHHHHHHCCCEECCCHHHHHHHCCEEECHHHHCCCCCCCCCCCCCCCEEEEEC DKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLIDQYGADTARLFTMFAAPPEQQ CCCCCEEEEECCCCCEEEEECHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHEECCCCHHH LEWSGAGVEGASRFLRRVWSFGYANREALASRAGFDAAALGDADKALRREIYSVLKQADF CEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCC DYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLREAYGVLLRVLYPVVPHVTYELWKALGY CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC ADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAALADDAF CHHHCCCCCCCCCCCCHHHHHHCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHH AKFGEGKPAKKIVVVPGRLVNIVV HHHCCCCCCCEEEECCCCEEEEEC >Mature Secondary Structure MHERYVPADVEAAAQGDWRAADAYKTQEDAQKPKFYCVSMLPYPSGKLHMGHVRNYTIND CCCCCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCEEECCCCCCCHHH VMYRYLRMNGYNVLMPMGWDAFGMPAENAAMANGVPPAKWTYDNIDYMKGQMQSMGLAID HHHHHHHHCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCEECCCHHHHHHHHHHCCEEEE WSREIATCKPDYYKWNQWLFLKMLEKGIAYKKTGTVNWDPVDQTVLANEQVIDGRGWRSG CCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHCCCEEECCCCCCCC ALVEKREIPMYYLRITQYADELLNDLDGLGWPERVKIMQQNWIGKSFGVNFGFPYELDGE CCEECCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCH KQLLRVFTTRADTIMGVTFCAIAAEHPLATRLAQGKPELQAFIDECKRGGVAEADMATME HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHH KKGVATGFSVTHPLTGEPVEVWIGNYVLMSYGEGAVMGVPGHDERDFAFAKKYGLPIKQV HCCCCCCCEECCCCCCCCCEEEECCEEEEECCCCCEEECCCCCCCCHHHHHHHCCCHHHH IAAEGHTYSLDAWQEWYGDKDIAVCINSGKYDGLGYAAAVDAVAADLKAGGFGDKQVTWR HHCCCCEEECHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEE LRDWGISRQRYWGTPIPIIHCPSCGDVPVPEKDLPVVLPEDLVPDGSGNPLAKSEAFLNC EHHCCCCCHHCCCCCCCEEECCCCCCCCCCCCCCCEECCHHCCCCCCCCCCCCCCCEEEE TCPKCGAAAKRETDTMDTFVDSSWYFSRYTAPDAETMVDARTDYWMPMDQYIGGIEHAIL CCCCCCCCCCCCCCHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCHHHHHCHHHHHHH HLLYSRFWTKVMRDLGLVKFGEPAKNLLTQGMVLNETYYREDAAGKKTWYNPADVTVTHD HHHHHHHHHHHHHHCCCEECCCHHHHHHHCCEEECHHHHCCCCCCCCCCCCCCCEEEEEC DKGRPVGATLNADGQPVVLGGIEKMSKSKNNGVDPQVLIDQYGADTARLFTMFAAPPEQQ CCCCCEEEEECCCCCEEEEECHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHEECCCCHHH LEWSGAGVEGASRFLRRVWSFGYANREALASRAGFDAAALGDADKALRREIYSVLKQADF CEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCC DYQRLQYNTVVSAAMKMLNAIDGAKGATPGVLREAYGVLLRVLYPVVPHVTYELWKALGY CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC ADEFGPLLDAPWPKVDEAALEQAEIELVLQVNGKVRGALKVAKDASREAIEAAALADDAF CHHHCCCCCCCCCCCCHHHHHHCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHH AKFGEGKPAKKIVVVPGRLVNIVV HHHCCCCCCCEEEECCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA