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The map label for this gene is gntP [H]

Identifier: 161525890

GI number: 161525890

Start: 2973150

End: 2974511

Strand: Reverse

Name: gntP [H]

Synonym: Bmul_2721

Alternate gene names: 161525890

Gene position: 2974511-2973150 (Counterclockwise)

Preceding gene: 161525891

Following gene: 161525889

Centisome position: 86.26

GC content: 64.83

Gene sequence:

>1362_bases
ATGGGGGCTGTCCAAGGCAGCATGCTGCTCGTATTCACGCTGATCGCGATCGCCGCGCTGATCCTGATGATCGCGCGCTT
CAAGATCTACCCGTTCCTGGTGCTGATCATCGTGTCGCTCGGCCTCGGTCTGGCCGTCGGCATGCCGATGGACAAGATCG
TCAAGTCGTTCGAGACGGGCACGGGCGGCACGCTCGGCCATATCGCGATCGTCGTCGGCCTCGGTACGATGCTCGGCAAG
ATGATGGCCGAGTCGGGCGGCGCCGAGCGGATCGCGACCACGCTGATCGACTGGTTCGGTGAGAAGAACATCCACTGGGC
GATGATGTTCGTCGCGATCATCGTCGGTCTGCCGGTGTTCTTCGAAGTCGGCTTCGTGCTGCTGATCCCGATCGCGTTCA
ACGTCGCGAAGCGTACCGGCAAGTCGCTGCTCGTCGTGGGCCTGCCGATGGTTGCGGGCCTGTCCGTCGTGCACGGGCTG
ATTCCGCCGCACCCGGCCGCGCTGCTGGCCGTTCAGCAATACGGCGCCGATATCGGCAAGACGATCGCGTTCGGTCTGAT
CGTCGGCGTGCCGACCGCGATCATCGCCGGTCCGCTGTTCGCGCTGACCATTTCGAAGTTCGTGAAGCTTGCGGAAAACA
ATCCGCTCGCGTCGCAGTTCGTCGACACGCGTGCCGGCGGCCGCGAGCGTCCGCTGCCGGGCTTCGGCATCACGCTGTTC
ACGATTCTCCTGCCGGTCGTGCTGATGCTCGTCGGCAGCTGGGCCGATCTGGTGTTCGCGCCGAAGTCGCTGCCGAACAA
CCTGCTGCGCTTTGCAGGCAATTCGGACGTCGCGCTGCTGATCGCCGTGCTCGTGAGCTTCTTCACGTTCGGCAAGCTGC
AGGGCTTCAATCGCGACCAGATCCAGAAGTTCTGCGGCGAGTGTCTCGCGCCGATCGCCGGCATCACGCTGATCGTGGGC
GCGGGCGGCGGCTTCGGCGGCGTCCTGCGCGACAGCGGGATTTCGCAGCAGATCGTCGAAACCGCGAAGCACGCGCACCT
GTCGCCGCTGCTGCTCGGCTGGTTCGTCGCCGCGCTGATGCGTCTCGCGACGGGTTCGGCGACGGTCGCGATGACGACCG
CATGCGGCATCGTCGCGCCGATCGCGGCCGCGGCCGGCACGACGGTCAGCCCGGAGCTGCTCGTGCTCGCCACGGGGTCG
GGCTCCCTGATCTTCTCGCACGTGAACGATGGCGGTTTCTGGCTGATCAAGGAATACTTCGGGATGACGGTCGGTCAGAC
GTTCAAGACGTGGTCGTTGCTGGAAACGATCATCTCGGTGCTCGGCCTCGGCTTCACGTTGCTGCTGAGCATGGTTCTGT
AA

Upstream 100 bases:

>100_bases
TCCTGACGGGGTGGGAACCCCCCGTGTATCGGAGACCTGCATAGCCGGGCATACTCGCTACCACTCGCCCGGTTTCGAAC
AATCCAAGGAGGAGTGCCAC

Downstream 100 bases:

>100_bases
CAAGGGGTAGTCAATGATTTTGATCGCAATGGGCGTGTCGGGCGCGGGCAAATCGCGAATCGGCGAAATGCTGGCGCAAC
GCCTGTCGTGCAGCTATACC

Product: gluconate transporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGAVQGSMLLVFTLIAIAALILMIARFKIYPFLVLIIVSLGLGLAVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLAENNPLASQFVDTRAGGRERPLPGFGITLF
TILLPVVLMLVGSWADLVFAPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL

Sequences:

>Translated_453_residues
MGAVQGSMLLVFTLIAIAALILMIARFKIYPFLVLIIVSLGLGLAVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGK
MMAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGL
IPPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLAENNPLASQFVDTRAGGRERPLPGFGITLF
TILLPVVLMLVGSWADLVFAPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL
>Mature_452_residues
GAVQGSMLLVFTLIAIAALILMIARFKIYPFLVLIIVSLGLGLAVGMPMDKIVKSFETGTGGTLGHIAIVVGLGTMLGKM
MAESGGAERIATTLIDWFGEKNIHWAMMFVAIIVGLPVFFEVGFVLLIPIAFNVAKRTGKSLLVVGLPMVAGLSVVHGLI
PPHPAALLAVQQYGADIGKTIAFGLIVGVPTAIIAGPLFALTISKFVKLAENNPLASQFVDTRAGGRERPLPGFGITLFT
ILLPVVLMLVGSWADLVFAPKSLPNNLLRFAGNSDVALLIAVLVSFFTFGKLQGFNRDQIQKFCGECLAPIAGITLIVGA
GGGFGGVLRDSGISQQIVETAKHAHLSPLLLGWFVAALMRLATGSATVAMTTACGIVAPIAAAAGTTVSPELLVLATGSG
SLIFSHVNDGGFWLIKEYFGMTVGQTFKTWSLLETIISVLGLGFTLLLSMVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=449, Percent_Identity=46.7706013363029, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1790716, Length=436, Percent_Identity=41.2844036697248, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI2367370, Length=428, Percent_Identity=41.8224299065421, Blast_Score=311, Evalue=8e-86,
Organism=Escherichia coli, GI1788707, Length=444, Percent_Identity=42.3423423423423, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI1790776, Length=432, Percent_Identity=34.4907407407407, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI48994939, Length=424, Percent_Identity=36.7924528301887, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1789097, Length=446, Percent_Identity=34.0807174887892, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47374; Mature: 47242

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GAVQGSMLLVFTLIAIAALILMIARFKIYPFLVLIIVSLGLGLAVGMPMDKIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC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CCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA