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The map label for this gene is gltK [H]

Identifier: 161525881

GI number: 161525881

Start: 2963178

End: 2963858

Strand: Reverse

Name: gltK [H]

Synonym: Bmul_2712

Alternate gene names: 161525881

Gene position: 2963858-2963178 (Counterclockwise)

Preceding gene: 161525882

Following gene: 161525880

Centisome position: 85.95

GC content: 64.46

Gene sequence:

>681_bases
GTGATGCATCAGTTCGACTGGAGTAGTATTCCCGGCGCGCTGCCGACGCTGTGGACGGGGGCGATCGTCACGTTCAAGAT
CACGCTGATCGCGATCGTGGTCGGGATCGTCTGGGGCACGCTGCTCGCGCTGATGCGCCTGTCGGGCGTGAAGCCGCTCG
CATGGTTCGCGAAGGCCTACGTGACGGTGTTCCGCTCGATCCCGCTCGTGATGGTGCTGCTGTGGTTCTTCCTGATCGTG
CCGCAGGTGCTGCAGGGCGTGCTCGGGCTGTCGCCGACGATCGACATCCGGCTCGCGTCGGCGATGGTCGCGTTCTCGCT
GTTCGAAGCCGCGTATTATTCCGAGATCATCCGCGCCGGCATCCAGGCGGTGCCGCGCGGGCAGGTGAACGCGGCGTTCG
CGCTCGGCATGAACTACGCGCAGGCGATGCGCCTCGTGATCCTGCCGCAGGCGTTTCGCGCGATGGTCCCGCTGCTGCTC
ACGCAGGCGATCGTGCTGTTCCAGGACACGTCGCTCGTGTACGTGATCAGTCTCGCGGACTTCTTCCGCACGGCCGCGAA
CATCGGCGATCGCGACGGCACGACCGTCGAGATGGTGCTGTTCGCCGGCGCCTGCTATTTCGTGATTTGCTCGGTGGCGT
CTGCCCTCGTCAAAGGTCTCCAGAAAAAGGTCACAAGATGA

Upstream 100 bases:

>100_bases
TCGCGGTCACGCTCGCGTACGTGCTCATCAACCTCGTCGTGATGGGGCTGATGCGCTGGATCGAAGGCCGCACGCGGCTG
CCCGGCTACATCGGAGGCAA

Downstream 100 bases:

>100_bases
TTTCCATCAAGAACGTTTCGAAGTGGTACGGCCAGTTTCAGGTTCTCACCGACTGCACGACCGAAGTGAAGAAGGGCGAG
GTGGTCGTCGTGTGCGGGCC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MMHQFDWSSIPGALPTLWTGAIVTFKITLIAIVVGIVWGTLLALMRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQVLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSVASALVKGLQKKVTR

Sequences:

>Translated_226_residues
MMHQFDWSSIPGALPTLWTGAIVTFKITLIAIVVGIVWGTLLALMRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQVLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSVASALVKGLQKKVTR
>Mature_226_residues
MMHQFDWSSIPGALPTLWTGAIVTFKITLIAIVVGIVWGTLLALMRLSGVKPLAWFAKAYVTVFRSIPLVMVLLWFFLIV
PQVLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLL
TQAIVLFQDTSLVYVISLADFFRTAANIGDRDGTTVEMVLFAGACYFVICSVASALVKGLQKKVTR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=72.0720720720721, Blast_Score=323, Evalue=5e-90,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=36.4485981308411, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=33.8095238095238, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786874, Length=187, Percent_Identity=31.5508021390374, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787030, Length=225, Percent_Identity=29.7777777777778, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=28.1938325991189, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=26.2672811059908, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788646, Length=208, Percent_Identity=25, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=24.2990654205607, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24682; Mature: 24682

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHQFDWSSIPGALPTLWTGAIVTFKITLIAIVVGIVWGTLLALMRLSGVKPLAWFAKAY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VTVFRSIPLVMVLLWFFLIVPQVLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FFRTAANIGDRDGTTVEMVLFAGACYFVICSVASALVKGLQKKVTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMHQFDWSSIPGALPTLWTGAIVTFKITLIAIVVGIVWGTLLALMRLSGVKPLAWFAKAY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VTVFRSIPLVMVLLWFFLIVPQVLQGVLGLSPTIDIRLASAMVAFSLFEAAYYSEIIRAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQAVPRGQVNAAFALGMNYAQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FFRTAANIGDRDGTTVEMVLFAGACYFVICSVASALVKGLQKKVTR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]