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The map label for this gene is mmgC [H]

Identifier: 161525739

GI number: 161525739

Start: 2798108

End: 2799295

Strand: Direct

Name: mmgC [H]

Synonym: Bmul_2570

Alternate gene names: 161525739

Gene position: 2798108-2799295 (Clockwise)

Preceding gene: 161525736

Following gene: 161525741

Centisome position: 81.14

GC content: 64.9

Gene sequence:

>1188_bases
ATGAGCGCTGCAACTTTTCATTGGGACGATCCGCTGCTGCTCGACCAGCAACTGACCGAGGACGAGCGCATGGTGCGCGA
CGCCGCGCACGCGTATGCGCAGGACAAGCTCGCGCCGCGCGTGACCGAGGCGTTTCGCCACGAGCGCACCGATGCCGCGA
TCTTTCGCGAGATGGGCGAAGTCGGCCTGCTTGGCCCGACGATTCCCGAGCAATACGGCGGCCCCGGGCTGAACTACGTC
AGCTACGGGCTGATCGCGCGCGAGGTCGAGCGTGTCGATTCGGGCTATCGGTCGATGATGTCCGTGCAATCGTCGCTCGT
GATGGTGCCGATCTACGAGTTCGGCTCCGACGCGCAGAAGGAGAAATACCTGCCGAAGCTCGCGACCGGCGAGTGGATCG
GCTGTTTCGGGCTGACCGAGCCGAACCACGGCTCGGACCCAGGCAGCATGGTCACGCGCGCGAAGAAGGTGCCGGGCGGG
TACTCGCTGTCGGGCGCGAAGATGTGGATCACGAACTCGCCGATCGCCGACGTGTTCGTCGTCTGGGCGAAGCTCGACGA
GGACGGCAAGGATACGATCCGCGGCTTCATCCTCGAGAAGGGCTGGAAAGGGTTGTCGGCGCCGGCGATCCACGGCAAGG
TCGGGCTGCGCGCGTCGATCACGGGCGAGATCGTGCTCGACGAGGTGTTCGTGCCCGAGGAAAACCTGATGCCGAACGTC
AGCGGCCTGCGCGGGCCGTTCACCTGCCTGAACTCGGCACGCTACGGGATCGCCTGGGGTGCGCTCGGCGCCGCGGAATC
GTGCTGGCATACCGCGCGCCAGTACGTGCTCGATCGCAAGCAGTTCGGTCGCCCGCTCGCCGCAAATCAGCTGATCCAGA
AAAAGCTCGCCGACATGCAGACCGAAATCACGCTCGGCCTGCAAGGCGTGCTGCGTCTGGGCCGGATGAAGGACGAAGGC
ACGGCGGCCGTCGAAATCACGTCGATCATGAAACGCAATTCGTGCGGCAAGGCGCTCGACATCGCGCGGCTCGCGCGCGA
CATGCTCGGTGGCAACGGCATCTCGGACGAATTCGGCGTCGCGCGCCACCTCGTCAACCTCGAAGTGGTCAATACGTATG
AAGGCACGCACGACATCCACGCACTGATCCTCGGACGCGCGCAAACCGGCATCCAGGCATTCTTCTGA

Upstream 100 bases:

>100_bases
GTCGTCGATGGTTGAAAGTGTCATCCGATGCTACACTGGGATCAATTTGCAAAACATTGTTCCGCACAGCGGAACTCCAG
TCAAGTCAGGAGATGACACG

Downstream 100 bases:

>100_bases
GCAATCGGCGCAGCGTGTCCGTATTACACGCGATGGGCGGAAACGACACGGCCCGCCCGGCATGACTGCCGGGCGGGCCG
TTTTGCGCATGCCGCCGATA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSAATFHWDDPLLLDQQLTEDERMVRDAAHAYAQDKLAPRVTEAFRHERTDAAIFREMGEVGLLGPTIPEQYGGPGLNYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YSLSGAKMWITNSPIADVFVVWAKLDEDGKDTIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Sequences:

>Translated_395_residues
MSAATFHWDDPLLLDQQLTEDERMVRDAAHAYAQDKLAPRVTEAFRHERTDAAIFREMGEVGLLGPTIPEQYGGPGLNYV
SYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGG
YSLSGAKMWITNSPIADVFVVWAKLDEDGKDTIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
>Mature_394_residues
SAATFHWDDPLLLDQQLTEDERMVRDAAHAYAQDKLAPRVTEAFRHERTDAAIFREMGEVGLLGPTIPEQYGGPGLNYVS
YGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGY
SLSGAKMWITNSPIADVFVVWAKLDEDGKDTIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNVS
GLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGT
AAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=395, Percent_Identity=66.5822784810127, Blast_Score=526, Evalue=1e-149,
Organism=Homo sapiens, GI7669494, Length=375, Percent_Identity=65.0666666666667, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=33.5106382978723, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=34.0116279069767, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=31.4516129032258, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=29.1553133514986, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=31.5104166666667, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=31.5104166666667, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4557231, Length=401, Percent_Identity=30.1745635910224, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI187960098, Length=401, Percent_Identity=30.1745635910224, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=32.183908045977, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=28.4574468085106, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI4501857, Length=379, Percent_Identity=28.2321899736148, Blast_Score=132, Evalue=6e-31,
Organism=Escherichia coli, GI87081958, Length=349, Percent_Identity=27.5071633237822, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786223, Length=337, Percent_Identity=25.8160237388724, Blast_Score=95, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17534353, Length=395, Percent_Identity=63.5443037974684, Blast_Score=512, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI17508101, Length=376, Percent_Identity=32.7127659574468, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17538396, Length=374, Percent_Identity=32.3529411764706, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.6849315068493, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=370, Percent_Identity=31.6216216216216, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=30.1333333333333, Blast_Score=167, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=34.7222222222222, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71985192, Length=280, Percent_Identity=33.2142857142857, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=28.4574468085106, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=28.4960422163588, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=32.2344322344322, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=25.4691689008043, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17505929, Length=395, Percent_Identity=25.5696202531646, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17551932, Length=398, Percent_Identity=24.3718592964824, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920834, Length=397, Percent_Identity=62.4685138539043, Blast_Score=490, Evalue=1e-139,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=32.1621621621622, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=32.3287671232877, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=32.258064516129, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=31.7460317460317, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI281363737, Length=408, Percent_Identity=30.3921568627451, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.952380952381, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43245; Mature: 43114

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAATFHWDDPLLLDQQLTEDERMVRDAAHAYAQDKLAPRVTEAFRHERTDAAIFREMGE
CCCCEECCCCCEEECHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCC
VGLLGPTIPEQYGGPGLNYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCHHH
EKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYSLSGAKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHE
VWAKLDEDGKDTIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
EEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHEEHHEECCHHCCHHHCC
>Mature Secondary Structure 
SAATFHWDDPLLLDQQLTEDERMVRDAAHAYAQDKLAPRVTEAFRHERTDAAIFREMGE
CCCEECCCCCEEECHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCC
VGLLGPTIPEQYGGPGLNYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIYEFGSDAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHCCCCHHH
EKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRAKKVPGGYSLSGAKMWITNSPIADVFV
HHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHE
VWAKLDEDGKDTIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENLMPNV
EEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
SGLRGPFTCLNSARYGIAWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCHHHHHCCCCCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFF
HHHHHEEEEEECCCCCHHEEHHEECCHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]