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The map label for this gene is nahR [H]

Identifier: 161525717

GI number: 161525717

Start: 2771921

End: 2772868

Strand: Direct

Name: nahR [H]

Synonym: Bmul_2548

Alternate gene names: 161525717

Gene position: 2771921-2772868 (Clockwise)

Preceding gene: 161525716

Following gene: 161525722

Centisome position: 80.38

GC content: 68.67

Gene sequence:

>948_bases
ATGGAAGACGACGACCGTACCGCCTCGCTCGACATCTGGCTCGTGCGCGTGCTGCGCACGCTGCTGCTCGAGCGCAGCGT
CACGCAGACCGCGCTGCGGCTCAACCAGACGCAGCCCGCGATCAGCACCGCACTGCGCAAGCTGCGCGAAACGCTGAACG
ACCCGATCCTCGTGCGCGGCAAGTCGGGCATGGTGCCGACCGAATACGGCGCGTCGCTGCTCGGCGCCGCGACGCGCGCG
CTGCGCGAGGTCGACTTCATCTCGACGCCGCACGGCGATTTCGATCCGTCGTCCGCGCGGCGCACATTCCGCATCGCCGC
GCCCGACTATCTGAACGATTTCTTCATGCCGACGCTGATCGAGCGCTTTCGCGATGCCGCGCCGCACGCGCATCTGGAAA
TCGATTCGCTGAATCCCGCGCTCGACCACGCGGGCGCGCTCGAATCGGGCGCACTCGATCTCGTGATCGGCAACTGGCCG
AAGCCCGATCCGCAGTTCGCGCGGCAGGACCTGTTCTCCGACACGATCGTGTGCCTGATGCGCGATGCGCATCCGCTCGC
ACGCGAGCCGCTCACGCGCGAAGCGTACGCGGCCGCCGCGCACGTCGCGCCCACGCCCTATACCGGCGACAAGCGCAACG
CGATCGAGATCGGCCTCGCGCGCGCGGGCCTCGCGCGGCGTGTCGTGACGACGCTGCCGTACTTCGGGATCGTCCCGCAG
GTGCTGCTGCAAACCGACCTGATCTTCACGACGACGCGCCGCTTCGCGACGCACTATGCGCAGCTGCTGCCGCTCGTCGT
CGTCCCGCCGCCGGTGCCGTTTCCGCGCATCAAGAGCTATCTGCTCACACATCCGCAGCCCGATCGGCCGACCGATATCG
CGTGGCTGTGCGCGCTGATGCAGAGCGTGTCCGACGAACTGACCGCCGCACGCGCGCGCAAGCGCTGA

Upstream 100 bases:

>100_bases
GATCAGCACGCTGCCGAAAGGCCGCGCGTGATGGCGGGTATCACGCACGCGCACGCACGGCTGCGGTAAGGTTACGCTTC
GCCCGGATCACCCCGCATCG

Downstream 100 bases:

>100_bases
GCCCGCGCGCGCGGCACGCGCGTCACGCCGCGCAGAACGTTTCCTGCAGATGCGTCCAGCGCACCGCGCCCGCGGCGTCG
CGTGCGAACACGGCGGTGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEDDDRTASLDIWLVRVLRTLLLERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGASLLGAATRA
LREVDFISTPHGDFDPSSARRTFRIAAPDYLNDFFMPTLIERFRDAAPHAHLEIDSLNPALDHAGALESGALDLVIGNWP
KPDPQFARQDLFSDTIVCLMRDAHPLAREPLTREAYAAAAHVAPTPYTGDKRNAIEIGLARAGLARRVVTTLPYFGIVPQ
VLLQTDLIFTTTRRFATHYAQLLPLVVVPPPVPFPRIKSYLLTHPQPDRPTDIAWLCALMQSVSDELTAARARKR

Sequences:

>Translated_315_residues
MEDDDRTASLDIWLVRVLRTLLLERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGASLLGAATRA
LREVDFISTPHGDFDPSSARRTFRIAAPDYLNDFFMPTLIERFRDAAPHAHLEIDSLNPALDHAGALESGALDLVIGNWP
KPDPQFARQDLFSDTIVCLMRDAHPLAREPLTREAYAAAAHVAPTPYTGDKRNAIEIGLARAGLARRVVTTLPYFGIVPQ
VLLQTDLIFTTTRRFATHYAQLLPLVVVPPPVPFPRIKSYLLTHPQPDRPTDIAWLCALMQSVSDELTAARARKR
>Mature_315_residues
MEDDDRTASLDIWLVRVLRTLLLERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRGKSGMVPTEYGASLLGAATRA
LREVDFISTPHGDFDPSSARRTFRIAAPDYLNDFFMPTLIERFRDAAPHAHLEIDSLNPALDHAGALESGALDLVIGNWP
KPDPQFARQDLFSDTIVCLMRDAHPLAREPLTREAYAAAAHVAPTPYTGDKRNAIEIGLARAGLARRVVTTLPYFGIVPQ
VLLQTDLIFTTTRRFATHYAQLLPLVVVPPPVPFPRIKSYLLTHPQPDRPTDIAWLCALMQSVSDELTAARARKR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=27.4247491638796, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081766, Length=273, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790147, Length=292, Percent_Identity=26.027397260274, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35039; Mature: 35039

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDDRTASLDIWLVRVLRTLLLERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEC
KSGMVPTEYGASLLGAATRALREVDFISTPHGDFDPSSARRTFRIAAPDYLNDFFMPTLI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
ERFRDAAPHAHLEIDSLNPALDHAGALESGALDLVIGNWPKPDPQFARQDLFSDTIVCLM
HHHHHCCCCCEEEECCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
RDAHPLAREPLTREAYAAAAHVAPTPYTGDKRNAIEIGLARAGLARRVVTTLPYFGIVPQ
HCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VLLQTDLIFTTTRRFATHYAQLLPLVVVPPPVPFPRIKSYLLTHPQPDRPTDIAWLCALM
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
QSVSDELTAARARKR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MEDDDRTASLDIWLVRVLRTLLLERSVTQTALRLNQTQPAISTALRKLRETLNDPILVRG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEC
KSGMVPTEYGASLLGAATRALREVDFISTPHGDFDPSSARRTFRIAAPDYLNDFFMPTLI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
ERFRDAAPHAHLEIDSLNPALDHAGALESGALDLVIGNWPKPDPQFARQDLFSDTIVCLM
HHHHHCCCCCEEEECCCCHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
RDAHPLAREPLTREAYAAAAHVAPTPYTGDKRNAIEIGLARAGLARRVVTTLPYFGIVPQ
HCCCHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
VLLQTDLIFTTTRRFATHYAQLLPLVVVPPPVPFPRIKSYLLTHPQPDRPTDIAWLCALM
HHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
QSVSDELTAARARKR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]