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The map label for this gene is galE [H]

Identifier: 161525670

GI number: 161525670

Start: 2716393

End: 2717415

Strand: Direct

Name: galE [H]

Synonym: Bmul_2501

Alternate gene names: 161525670

Gene position: 2716393-2717415 (Clockwise)

Preceding gene: 161525669

Following gene: 161525671

Centisome position: 78.77

GC content: 65.79

Gene sequence:

>1023_bases
ATGAGCGCTAAAGGCACCATCCTCGTTACGGGCGGCGCGGGGTATATCGGCTCGCACACGGCTGTCGAGCTGCTCGACAA
CGGCTACGACGTCGTGATCGTCGACAACCTCGTCAACAGCAAGGCCGAATCGGTGCGGCGCATCGAACGCATCACCGGCA
AGCAGCCCGCGTTCCATCAGGTCGACGTTTGCGACGAAGCCGCGCTCGCGAAAGTGTTCGACGCACATCCGATCACCGGC
ACGATTCACTTCGCGGCGCTGAAGGCCGTCGGCGAATCGGTTGCGAAGCCGCTCGAGTACTACCAGAACAACCTCGGCGG
GCTGCTGACCGTGCTGAAGGTCATGCGCGCGCGCAACGTGAAGCAGTTCGTGTTCAGCTCGTCGGCGACCGTGTACGGCG
TGCCCGAGCGCTCGCCGATCGACGAGTCGTTCCCGCTCTCCGCGACGAATCCGTACGGCCAGTCGAAGCTGATCGCCGAG
CAGATCCTGCGCGATCTCGAAGTGTCCGATCCGTCGTGGCGGATCGCAACGCTGCGCTATTTCAACCCGGTCGGTGCGCA
TGCGAGCGGGCTGATCGGCGAGGATCCGGCCGGCATTCCGAACAACCTGATGCCTTATGTCGCGCAGGTCGCCGTCGGCA
AGCTCGAGAAGCTGCGCGTGTTCGGCTCCGACTATCCGACGCCCGACGGCACCGGCGTGCGCGACTACATCCACGTCGTC
GATCTCGCGAAGGGGCACATCGCCGCGCTCGATGCGCTCGTGAAGCGCGACGCGAGCTTCGTCGTGAACCTCGGCACCGG
CCAGGGCTACAGCGTGCTTGATGTCGTACGCGCGTTCGAGAAGGCGTCGGGCCGCCCGGTGCCGTACGAGATCGTCGCGC
GCCGCCCGGGCGACGTCGCCGAGTGCTATGCGAACCCGCAGGCGGCCGCCGACATCATCGGCTGGCGTGCGACGCTCGGC
CTCGACGACATGTGTGCCGACCACTGGCGATGGCAGGAGGCGAACCCGCGCGGTTTTGTATAA

Upstream 100 bases:

>100_bases
CAAGGTCGCGGCCGAATTCGACGAGCAGCAGGTCGTCGAACGCTATCGGCGTACTATTCACACGTTGACAGGTATTACAT
TTTGAAGGAGCACATGAGCA

Downstream 100 bases:

>100_bases
TCCGCTGTCCATTTTTCGAGCGATCCCATGCTCAGCTTCGCGTCCGGCTTCATCGTTTCCCTGCTCGTTACGCTGTTCAT
CGTGCGCTATGCGCATCTAC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKQPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNLGGLLTVLKVMRARNVKQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLAKGHIAALDALVKRDASFVVNLGTGQGYSVLDVVRAFEKASGRPVPYEIVARRPGDVAECYANPQAAADIIGWRATLG
LDDMCADHWRWQEANPRGFV

Sequences:

>Translated_340_residues
MSAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKQPAFHQVDVCDEAALAKVFDAHPITG
TIHFAALKAVGESVAKPLEYYQNNLGGLLTVLKVMRARNVKQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAE
QILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
DLAKGHIAALDALVKRDASFVVNLGTGQGYSVLDVVRAFEKASGRPVPYEIVARRPGDVAECYANPQAAADIIGWRATLG
LDDMCADHWRWQEANPRGFV
>Mature_339_residues
SAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKQPAFHQVDVCDEAALAKVFDAHPITGT
IHFAALKAVGESVAKPLEYYQNNLGGLLTVLKVMRARNVKQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQ
ILRDLEVSDPSWRIATLRYFNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVVD
LAKGHIAALDALVKRDASFVVNLGTGQGYSVLDVVRAFEKASGRPVPYEIVARRPGDVAECYANPQAAADIIGWRATLGL
DDMCADHWRWQEANPRGFV

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=59.1176470588235, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=59.1176470588235, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=59.1176470588235, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=28.1021897810219, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=56.8862275449102, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI48994969, Length=250, Percent_Identity=26.4, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=25.8823529411765, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=56.8513119533528, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=56.5217391304348, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI115532424, Length=338, Percent_Identity=24.8520710059172, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17568069, Length=329, Percent_Identity=24.0121580547112, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=347, Percent_Identity=54.4668587896254, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=56.268221574344, Blast_Score=398, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36718; Mature: 36587

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKQPAFHQ
CCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNLGGLLTVLKVMRARNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALVKRDASFVVNLGTGQGYSVLDVVRAFEKASGRPVPYEIVARRPGDVA
HHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCHH
ECYANPQAAADIIGWRATLGLDDMCADHWRWQEANPRGFV
HHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SAKGTILVTGGAGYIGSHTAVELLDNGYDVVIVDNLVNSKAESVRRIERITGKQPAFHQ
CCCCCEEEECCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCCC
VDVCDEAALAKVFDAHPITGTIHFAALKAVGESVAKPLEYYQNNLGGLLTVLKVMRARNV
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KQFVFSSSATVYGVPERSPIDESFPLSATNPYGQSKLIAEQILRDLEVSDPSWRIATLRY
HHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEE
FNPVGAHASGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHVV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHH
DLAKGHIAALDALVKRDASFVVNLGTGQGYSVLDVVRAFEKASGRPVPYEIVARRPGDVA
HHCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCHH
ECYANPQAAADIIGWRATLGLDDMCADHWRWQEANPRGFV
HHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]