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The map label for this gene is add [H]

Identifier: 161525546

GI number: 161525546

Start: 2588773

End: 2589798

Strand: Direct

Name: add [H]

Synonym: Bmul_2376

Alternate gene names: 161525546

Gene position: 2588773-2589798 (Clockwise)

Preceding gene: 161525545

Following gene: 161525547

Centisome position: 75.07

GC content: 65.98

Gene sequence:

>1026_bases
ATGACTCCGACATTCAAGAACAAGATCGCTCGCGCGCCGAAGGCCGAGCTGCATATCCATATCGAAGGTTCGCTCGAGCC
CGAGCTGATCTTCGCGCTCGCGCAGCGCAACGGCGTGAAGCTTCCCTACGATTCGATCGACGCGCTGCGCGCCGCGTACG
CGTTCACCGATCTGCAGTCGTTCCTCGACATCTACTACGCGGGCGCGAGCGTGCTGCTGACCGAGCAGGACTTCTACGAC
ATGACCGCCGCGTACTGCGAACGCGCGCTCGCGGACAACGTCGTCCATACCGAGCTGTTCTTCGATCCGCAGACGCATAC
CGCGCGCGGCGTGCCGATCGAGACGGTCGTCGCCGGCATCGAGCGCGCGCTCGCGGATGCGGAAAAGCGCGGGCTGTCGA
GCAAGCTGATTCTGTGCTTTCTGCGCCATCTGCCGGAAGAAGATGCGCTCGCAACGTTCGAATCGGCGCTGCCGCTGTTC
GAGCGCTATCGTCACCGGCTGATCGGCGTCGGCCTCGACTCGTCCGAGCTCGGCCATCCGCCGACGAAGTTCGCGCGCGT
ATTCGACAAGGCACGGGCGCTCGGGCTGAAGCTCGTCGCGCATGCGGGCGAGGAAGGCCCGCCCGCGTACATCTACGAAG
CGCTCGACGTGCTGAAGGTCGACCGGATCGACCACGGCGTGCGCGCGATCGAGGACGGTGCGCTCGTCGAACGGCTCGCG
CGCACGCGCACGGCGCTGACCGTGTGCCCGCTGTCGAACCTGAAGCTCTGCGTGTTCGACGACATGTCGAAGCACACGCT
GAAGGCGCTGCTCGACCGCGGTGTTGCGGTGACGATCAATTCCGACGATCCCGCCTATTTCGGCGGCTACGTCAACGACA
ACTATTTCGCGACGGTCGAGGCGCTGCAGCTCGGCGACGCCGACGTGCATGCGGTGATCCGCAACGGCTTCGAGGCGTCG
TTCGTCGACGCCGCGCAGCGCGACGCGCTGATCGCGCGGCTCGACGCGTACTGGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
TCGCGATCTCGGTGGCCGCGCAGCTGCTGCAGGCCGTCGAGGCGAACGCGCAGGTGCCGGCGCACGCTTCCCCTACTCTC
TGACCGACCATCACGACGCC

Downstream 100 bases:

>100_bases
CGGCTGCCATCGAGGCGACGGACAGATGATCACGCACCGCACCGGCCTGCATGTCGCGACGACGGGACGCGCGCCGCACC
GCACGTCGATGCGGTGCGAC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTPTFKNKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLPYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYCERALADNVVHTELFFDPQTHTARGVPIETVVAGIERALADAEKRGLSSKLILCFLRHLPEEDALATFESALPLF
ERYRHRLIGVGLDSSELGHPPTKFARVFDKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRAIEDGALVERLA
RTRTALTVCPLSNLKLCVFDDMSKHTLKALLDRGVAVTINSDDPAYFGGYVNDNYFATVEALQLGDADVHAVIRNGFEAS
FVDAAQRDALIARLDAYWRAA

Sequences:

>Translated_341_residues
MTPTFKNKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLPYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYCERALADNVVHTELFFDPQTHTARGVPIETVVAGIERALADAEKRGLSSKLILCFLRHLPEEDALATFESALPLF
ERYRHRLIGVGLDSSELGHPPTKFARVFDKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRAIEDGALVERLA
RTRTALTVCPLSNLKLCVFDDMSKHTLKALLDRGVAVTINSDDPAYFGGYVNDNYFATVEALQLGDADVHAVIRNGFEAS
FVDAAQRDALIARLDAYWRAA
>Mature_340_residues
TPTFKNKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLPYDSIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYDM
TAAYCERALADNVVHTELFFDPQTHTARGVPIETVVAGIERALADAEKRGLSSKLILCFLRHLPEEDALATFESALPLFE
RYRHRLIGVGLDSSELGHPPTKFARVFDKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRAIEDGALVERLAR
TRTALTVCPLSNLKLCVFDDMSKHTLKALLDRGVAVTINSDDPAYFGGYVNDNYFATVEALQLGDADVHAVIRNGFEASF
VDAAQRDALIARLDAYWRAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=364, Percent_Identity=24.1758241758242, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI1787910, Length=334, Percent_Identity=29.3413173652695, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32565969, Length=347, Percent_Identity=23.342939481268, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538512, Length=347, Percent_Identity=23.342939481268, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=44.4776119402985, Blast_Score=289, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37651; Mature: 37520

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTFKNKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLPYDSIDALRAAYAFTDLQS
CCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYCERALADNVVHTELFFDPQTHTARGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ERALADAEKRGLSSKLILCFLRHLPEEDALATFESALPLFERYRHRLIGVGLDSSELGHP
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
PTKFARVFDKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRAIEDGALVERLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RTRTALTVCPLSNLKLCVFDDMSKHTLKALLDRGVAVTINSDDPAYFGGYVNDNYFATVE
HHHHEEEEECCCCCEEEEECCCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEE
ALQLGDADVHAVIRNGFEASFVDAAQRDALIARLDAYWRAA
EHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPTFKNKIARAPKAELHIHIEGSLEPELIFALAQRNGVKLPYDSIDALRAAYAFTDLQS
CCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYCERALADNVVHTELFFDPQTHTARGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHH
ERALADAEKRGLSSKLILCFLRHLPEEDALATFESALPLFERYRHRLIGVGLDSSELGHP
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCC
PTKFARVFDKARALGLKLVAHAGEEGPPAYIYEALDVLKVDRIDHGVRAIEDGALVERLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
RTRTALTVCPLSNLKLCVFDDMSKHTLKALLDRGVAVTINSDDPAYFGGYVNDNYFATVE
HHHHEEEEECCCCCEEEEECCCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEE
ALQLGDADVHAVIRNGFEASFVDAAQRDALIARLDAYWRAA
EHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA