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The map label for this gene is arsC [H]

Identifier: 161525485

GI number: 161525485

Start: 2527514

End: 2527936

Strand: Reverse

Name: arsC [H]

Synonym: Bmul_2315

Alternate gene names: 161525485

Gene position: 2527936-2527514 (Counterclockwise)

Preceding gene: 161525486

Following gene: 161525484

Centisome position: 73.31

GC content: 64.3

Gene sequence:

>423_bases
ATGAACACCATCACGATCTACCACAACCCCGCCTGCGGCACCTCGCGCAACGTGCTCGGACTGATCCGCAACAGCGGCGA
AGAACCGACCATCATCGAGTACCTGAAAACGCCGCCCGATCGCGACACGCTCCAGGCGTTGATCGCCGCGATGGGCGTGC
CGGTGCGCGCTGTGCTGCGCGAGAAAGGCACACCCTATGCCGAACTCGACCTGGGCAAACCGAAGTGGAGCGATGACGAC
CTGATCGGTTTCATGCTCCAGCATCCCATCCTCATCAACCGGCCGATCGTGGTCACGCCGCTGGGCACGAAACTGTGTCG
GCCCTCGGAAGCCGTGCTCGATCTGCTGCCGCAGCCGCAGCGCGGCGCGTTCAACAAGGAAGACGGCGAGCCGGTGGTCG
ATCAGGACGGCCGCCGTGTCTGA

Upstream 100 bases:

>100_bases
ATCGAGGTGCCGGTGATGCTGCTGGTGGTGCGCGTGGTCAACCGCTCGCGTGGCTGGTACGAACGCCGCGCGACCGCTTC
GTAATCTTCAAGGTCATCCC

Downstream 100 bases:

>100_bases
ATCCCGTCTCGACCTGCCGAACATCGACACGGCGCTGTTCCAGCAACCGGACACCGAACACCTGTTCGCGCCGGCACGGG
CCACGCACGCGCCGCGCTTC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNTITIYHNPACGTSRNVLGLIRNSGEEPTIIEYLKTPPDRDTLQALIAAMGVPVRAVLREKGTPYAELDLGKPKWSDDD
LIGFMLQHPILINRPIVVTPLGTKLCRPSEAVLDLLPQPQRGAFNKEDGEPVVDQDGRRV

Sequences:

>Translated_140_residues
MNTITIYHNPACGTSRNVLGLIRNSGEEPTIIEYLKTPPDRDTLQALIAAMGVPVRAVLREKGTPYAELDLGKPKWSDDD
LIGFMLQHPILINRPIVVTPLGTKLCRPSEAVLDLLPQPQRGAFNKEDGEPVVDQDGRRV
>Mature_140_residues
MNTITIYHNPACGTSRNVLGLIRNSGEEPTIIEYLKTPPDRDTLQALIAAMGVPVRAVLREKGTPYAELDLGKPKWSDDD
LIGFMLQHPILINRPIVVTPLGTKLCRPSEAVLDLLPQPQRGAFNKEDGEPVVDQDGRRV

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=140, Percent_Identity=70, Blast_Score=205, Evalue=7e-55,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=39.4736842105263, Blast_Score=90, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 15450; Mature: 15450

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTITIYHNPACGTSRNVLGLIRNSGEEPTIIEYLKTPPDRDTLQALIAAMGVPVRAVLR
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCHHHHHH
EKGTPYAELDLGKPKWSDDDLIGFMLQHPILINRPIVVTPLGTKLCRPSEAVLDLLPQPQ
HCCCCEEEEECCCCCCCCCHHHHHHHHCCEEECCCEEEEECCCHHCCCHHHHHHHCCCCC
RGAFNKEDGEPVVDQDGRRV
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNTITIYHNPACGTSRNVLGLIRNSGEEPTIIEYLKTPPDRDTLQALIAAMGVPVRAVLR
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCEEHHHCCCCCHHHHHHHHHHHCCCHHHHHH
EKGTPYAELDLGKPKWSDDDLIGFMLQHPILINRPIVVTPLGTKLCRPSEAVLDLLPQPQ
HCCCCEEEEECCCCCCCCCHHHHHHHHCCEEECCCEEEEECCCHHCCCHHHHHHHCCCCC
RGAFNKEDGEPVVDQDGRRV
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]