Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 161525477

GI number: 161525477

Start: 2521622

End: 2522587

Strand: Direct

Name: htpX [H]

Synonym: Bmul_2307

Alternate gene names: 161525477

Gene position: 2521622-2522587 (Clockwise)

Preceding gene: 161525476

Following gene: 161525478

Centisome position: 73.12

GC content: 66.77

Gene sequence:

>966_bases
ATGATCCGTCATCATCCCAATGACCCGCGCGCGGCGTTGTTGCAACACCGCTGGCTCAACCGCCTGCAGACCGGGCTGTT
GATCCTGACCCTGGTCGGGATCGCAGCCGCCGCAGGAAGCCTGCTGTTCGGGGAAAGCGGCCTGTGGCTCACGCTGTTTG
CAGTTGCAGGCACGCTGTTGCTGGAACCGGCAGCCGCATCCGTCTTGACCTTGCGCCTGTACCGCGCACGGGCTTTATAC
CCGCACGAAGCCCCCGAGATTTGGGCCCTGTTGCGCGAGCTGTCCGCCCGTGCCGGTTTGTCCGCCACGCCGGTGCCGCA
CTACGTGCCCAGTGCCGTCGTCAACGCCTTCGCCACCGGCTCGAAGCAGCATGCATCGATCGCCCTTACCGATGGCCTGC
TGCGCAACCTGAGTTCGCGCGAACTGGCGGGTGTGCTCGCGCACGAGGTCGCGCACATCGCTAATGAGGATCTGCGTGTC
ATGGGGCTGGCGGATTCCGTCAGTCGCCTCACGAGCCTGCTGGCTATGGTCGGACAGATCGCTATTGTGTTCAGCTTGCC
CGCACTGCTGGCCGGCGCGGTGGCGGTCAATTGGCCTGGACTGCTTCTGCTGGCCGCCTCGCCCCAGCTGGCCCTGCTCG
CACAGCTCGGTTTGTCTCGCGTGCGTGAGTTCGACGCCGACCGCCTCGCTGCGGAACTGACTGGCGACCCGCAGGGGCTT
GCGTCCGCGCTGGCGAAAATCGAGCGGGTCAGCCGCTCCTGGCGTGCCTGGTTGTGGCCGGGATGGGGCAATCCCGAACC
CTCCTGGTTGCGCACGCATCCGGCCACGCAAGAACGCATCTCACGCCTACTGACGTTGGCGCCTGGGCCAGCATCAGCGT
TGCCACTCCACGCGCCCCATTTCTTGCCGGAATCTGCTGTGACGCCGCGCCCGCCGCGCTGGCGCCCGAGCGGGCTATGG
CGCTGA

Upstream 100 bases:

>100_bases
CCGGGCAAGGTTGCAGCGCTTGCAGGCGCTACGCTGGCCTTGGGCATTACCTATTGGTTGCTGCGCGAGCGCGACGACCG
CTCCGCCGAGACATCTGAGC

Downstream 100 bases:

>100_bases
TTGCCTATCAACAGGAGACTTCTCATGGCCTACCCCGACCCGTACCAACGTCCCGCGCCGGACCACTTCGTCCGGCGCTG
GCTCTTCATCACCGCCTGTA

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIRHHPNDPRAALLQHRWLNRLQTGLLILTLVGIAAAAGSLLFGESGLWLTLFAVAGTLLLEPAAASVLTLRLYRARALY
PHEAPEIWALLRELSARAGLSATPVPHYVPSAVVNAFATGSKQHASIALTDGLLRNLSSRELAGVLAHEVAHIANEDLRV
MGLADSVSRLTSLLAMVGQIAIVFSLPALLAGAVAVNWPGLLLLAASPQLALLAQLGLSRVREFDADRLAAELTGDPQGL
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPGPASALPLHAPHFLPESAVTPRPPRWRPSGLW
R

Sequences:

>Translated_321_residues
MIRHHPNDPRAALLQHRWLNRLQTGLLILTLVGIAAAAGSLLFGESGLWLTLFAVAGTLLLEPAAASVLTLRLYRARALY
PHEAPEIWALLRELSARAGLSATPVPHYVPSAVVNAFATGSKQHASIALTDGLLRNLSSRELAGVLAHEVAHIANEDLRV
MGLADSVSRLTSLLAMVGQIAIVFSLPALLAGAVAVNWPGLLLLAASPQLALLAQLGLSRVREFDADRLAAELTGDPQGL
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPGPASALPLHAPHFLPESAVTPRPPRWRPSGLW
R
>Mature_321_residues
MIRHHPNDPRAALLQHRWLNRLQTGLLILTLVGIAAAAGSLLFGESGLWLTLFAVAGTLLLEPAAASVLTLRLYRARALY
PHEAPEIWALLRELSARAGLSATPVPHYVPSAVVNAFATGSKQHASIALTDGLLRNLSSRELAGVLAHEVAHIANEDLRV
MGLADSVSRLTSLLAMVGQIAIVFSLPALLAGAVAVNWPGLLLLAASPQLALLAQLGLSRVREFDADRLAAELTGDPQGL
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPGPASALPLHAPHFLPESAVTPRPPRWRPSGLW
R

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=298, Percent_Identity=28.1879194630872, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 34558; Mature: 34558

Theoretical pI: Translated: 11.32; Mature: 11.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRHHPNDPRAALLQHRWLNRLQTGLLILTLVGIAAAAGSLLFGESGLWLTLFAVAGTLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LEPAAASVLTLRLYRARALYPHEAPEIWALLRELSARAGLSATPVPHYVPSAVVNAFATG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SKQHASIALTDGLLRNLSSRELAGVLAHEVAHIANEDLRVMGLADSVSRLTSLLAMVGQI
CCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AIVFSLPALLAGAVAVNWPGLLLLAASPQLALLAQLGLSRVREFDADRLAAELTGDPQGL
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPGPASALPLHAPH
HHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
FLPESAVTPRPPRWRPSGLWR
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRHHPNDPRAALLQHRWLNRLQTGLLILTLVGIAAAAGSLLFGESGLWLTLFAVAGTLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHH
LEPAAASVLTLRLYRARALYPHEAPEIWALLRELSARAGLSATPVPHYVPSAVVNAFATG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
SKQHASIALTDGLLRNLSSRELAGVLAHEVAHIANEDLRVMGLADSVSRLTSLLAMVGQI
CCCCCEEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHH
AIVFSLPALLAGAVAVNWPGLLLLAASPQLALLAQLGLSRVREFDADRLAAELTGDPQGL
HHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ASALAKIERVSRSWRAWLWPGWGNPEPSWLRTHPATQERISRLLTLAPGPASALPLHAPH
HHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
FLPESAVTPRPPRWRPSGLWR
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA