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The map label for this gene is aaeR [H]

Identifier: 161525037

GI number: 161525037

Start: 2033891

End: 2034832

Strand: Reverse

Name: aaeR [H]

Synonym: Bmul_1865

Alternate gene names: 161525037

Gene position: 2034832-2033891 (Counterclockwise)

Preceding gene: 161525042

Following gene: 161525036

Centisome position: 59.01

GC content: 68.26

Gene sequence:

>942_bases
ATGGATACGTTACAAAACATGCGGGTATTCGTTCGCGTGGTCGACGCCGGTAGCTTCACCGCCGCCGCCCAGCAGATGAA
TTCGACGACCGCCTATGCGTCGCGCGCGGTGTCCGATCTGGAGGCGCATCTGCGCACGCGGCTGCTGAACCGCACGACGC
GCCGGATCGCGCTGACCGAAGCCGGCGAGCGCTATCTGCAGCGCTGCGAGCAGATCCTCGCGTATGTCGACCAAGCCGAA
GCCGAGGCAGGCGACGCGCATGCGCGCCCGTCCGGCAAGCTGAAGGTCCACTGCTTCACGAGCCTCGGCCAGCACTACCT
GGTGCCGGCCGTCGCGCGCTACCGCGAGCGCTATCCCGACGTACACGTCGAGCTGACGCTCGCGCAGCGGATGCCCGATC
TGCTCGACGAGGGGTACGACGTCGCGATCGTCGTCGGCCGCGATCTGCCCGATTCGGGGCTCGTGTCGCAGCGGCTCGGC
GAGAGCTACAGCGTCGTGTGCGCGTCGACCGCCTACGTCGCCGCGCATGGCGCGCCGCAGTGTCCGGCCGACCTCGCGCA
GCACGTGTGCCTCGGGATGGTCGCGCCCGGTTTCCACTACGACGAATGGACGCTGACCGGCCCCGACGGCGACGAGTCGG
TGCCCGTCACTGCGCCGCCGTTTCGCGTGAACGTCGCCGAGGCGCTGGCCGTCGCCGTGCGGGAAGGGATGGGGATCGGC
GGGCTGCCGCTGTATTCGGCGATCGGCGGGCTGCGCAGCGGGCAGATCGTGCGCGTGATGCCCGAATACCGGTCTCACGT
GATGAACATCTACGCGCTGTATGCGTCGCGCCAGTATCTCGACGCAAAAATCCGCACCTGGGTCGATTTCCTGCGCGACG
CATTGCCGACGACGCTCGCCGCCGACGAAGCGGCCCTCGAACAGTGCATGCGCGCGACATGA

Upstream 100 bases:

>100_bases
CTGAATAAATGGACAACGGTGCAAGGGATTTTTACGGATATTGAGACAATATTGGTGGGTCTCTGTGCAACAATCCGTCC
GGATTCAAACGGGAAACGGG

Downstream 100 bases:

>100_bases
CGACGCAGGGGCGCGCGATCTGACTAGATTTGTCGTTCGCGCAACATTTTTTTACGATCGATCGCCGGACAGTTTGATAC
TGTTTCAGTCATCGAGGTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAVARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASTAYVAAHGAPQCPADLAQHVCLGMVAPGFHYDEWTLTGPDGDESVPVTAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGGLRSGQIVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDALPTTLAADEAALEQCMRAT

Sequences:

>Translated_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAVARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASTAYVAAHGAPQCPADLAQHVCLGMVAPGFHYDEWTLTGPDGDESVPVTAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGGLRSGQIVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDALPTTLAADEAALEQCMRAT
>Mature_313_residues
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTEAGERYLQRCEQILAYVDQAE
AEAGDAHARPSGKLKVHCFTSLGQHYLVPAVARYRERYPDVHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLG
ESYSVVCASTAYVAAHGAPQCPADLAQHVCLGMVAPGFHYDEWTLTGPDGDESVPVTAPPFRVNVAEALAVAVREGMGIG
GLPLYSAIGGLRSGQIVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDALPTTLAADEAALEQCMRAT

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=36.0544217687075, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=34.7972972972973, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=32.1799307958478, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=29.616724738676, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=28.8079470198675, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1787128, Length=296, Percent_Identity=26.6891891891892, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=23.5494880546075, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789173, Length=255, Percent_Identity=28.2352941176471, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=24.7457627118644, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=122, Percent_Identity=28.6885245901639, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=154, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34258; Mature: 34258

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAVARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASTAYVAAHGAPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEEHHHHHEECCCCC
CPADLAQHVCLGMVAPGFHYDEWTLTGPDGDESVPVTAPPFRVNVAEALAVAVREGMGIG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCC
GLPLYSAIGGLRSGQIVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDALPTTLA
CCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ADEAALEQCMRAT
HHHHHHHHHHHCC
>Mature Secondary Structure
MDTLQNMRVFVRVVDAGSFTAAAQQMNSTTAYASRAVSDLEAHLRTRLLNRTTRRIALTE
CCCHHHHEEEHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGERYLQRCEQILAYVDQAEAEAGDAHARPSGKLKVHCFTSLGQHYLVPAVARYRERYPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHCCC
VHVELTLAQRMPDLLDEGYDVAIVVGRDLPDSGLVSQRLGESYSVVCASTAYVAAHGAPQ
EEEEEEHHHHCHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEEEHHHHHEECCCCC
CPADLAQHVCLGMVAPGFHYDEWTLTGPDGDESVPVTAPPFRVNVAEALAVAVREGMGIG
CHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCC
GLPLYSAIGGLRSGQIVRVMPEYRSHVMNIYALYASRQYLDAKIRTWVDFLRDALPTTLA
CCHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ADEAALEQCMRAT
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]