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The map label for this gene is apbA [H]

Identifier: 161524861

GI number: 161524861

Start: 1858778

End: 1859833

Strand: Reverse

Name: apbA [H]

Synonym: Bmul_1688

Alternate gene names: 161524861

Gene position: 1859833-1858778 (Counterclockwise)

Preceding gene: 161524862

Following gene: 161524860

Centisome position: 53.93

GC content: 63.73

Gene sequence:

>1056_bases
ATGCGGGCAGCCATGGTAGGCGCGGGTTCACTCGGGACGATTATCGGGGCGCTGATGACGCGTGCCGGCAAACAGATCGA
TCTCGTCGACAGTCATCAGGAACACGTCGACGCGCTCAATGCATTTGGCGCGACGATCACCGGCGCCTTGGAGCTCAATG
TTCCGGTTCGCGCCTTGACGCCCGATCAACTGACGGGGCGCTACGACCTCGTGTTCCTGTTGACGAAGCAGACGGTCAAT
CAGGCAATCCTGACGACGCTACTGCCGCACCTGCATGCCGACAGCATCGTCTGCACCTTGCAGAACGGCATACCCGAGCA
TGCGGTAGCGGCGCTCGTCGGCGCGGAGAGGACAGTAGGCGGCGCCGTGGGCTTCGGCGCGACGTGGCTGAAGCCCGGTG
TGTCGTCGCTTACCTCGAGCTATGAGGCTGTGCGCAAGTTTGCGTTCGAGATCGGCGAGATCGACGGCGTGATCCGTCCG
CGCCTGAAAGTCGTGCAGGCGTATCTGGAGTGCGTCGGCACGACCGAGATCCGTTCCGACCTGATGGGCATCCGGTTTTC
GAAACTCCTGATGAACGCGACGTTCAGCGGCATGTCGGCGGCGCTTGGCTGCACGTTCGGCGACGTGCTCGACGATGCCC
GTGCGATGGCGTGCCTTGCCTTCGTGGCCGACGAGTGCATCAAGGTCGCGCATGCGCACGGCGTACGCCTCGCCGAGATG
CAGGGCAAGGATTTCGAGCGTTTCGAACTGGCGAGCGCCGCCGACATTCCTTCGAAGATGCCGCTCTATCGCGAGATCTG
GGGGCCGCACGCGAAGCTGAAAGCCAGCATGCTGCAGGACCTCGAAAAACGGCGCGATACCGAAATCGGCTACATCAACG
GCCTGATCTGCGCGAAGGGTCGCGAGCGAGGTGTGCCGACGCCGTTCAACGACAGGATCATCGAGCTCGTCGCCGAGGCG
CAAGCGCGGCGCGGCGTCAACGACTTCGGTTATCTGGCGCGCTTCGACGACCTGCTCGCCGCTCACGTGCGCGATCTTCC
CGCTCTCGCGCGGTGA

Upstream 100 bases:

>100_bases
TCATCTATGCCATCGTGCTCGCGAGCATTGCGTTCCTCGTGTTGCCGGCCGGGCTCTGAAGGTCACATCGCTTGAACACA
GTCATTGCGGAGATACACGA

Downstream 100 bases:

>100_bases
GACGCCTGATGGACACGCAAGCCCATCGATTCAGTTTTCCGTCCACTGCCCCACGAGGCACCTCATGAGCAAGAAGACCA
TCATCAGCTGCGCCATCACG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRAAMVGAGSLGTIIGALMTRAGKQIDLVDSHQEHVDALNAFGATITGALELNVPVRALTPDQLTGRYDLVFLLTKQTVN
QAILTTLLPHLHADSIVCTLQNGIPEHAVAALVGAERTVGGAVGFGATWLKPGVSSLTSSYEAVRKFAFEIGEIDGVIRP
RLKVVQAYLECVGTTEIRSDLMGIRFSKLLMNATFSGMSAALGCTFGDVLDDARAMACLAFVADECIKVAHAHGVRLAEM
QGKDFERFELASAADIPSKMPLYREIWGPHAKLKASMLQDLEKRRDTEIGYINGLICAKGRERGVPTPFNDRIIELVAEA
QARRGVNDFGYLARFDDLLAAHVRDLPALAR

Sequences:

>Translated_351_residues
MRAAMVGAGSLGTIIGALMTRAGKQIDLVDSHQEHVDALNAFGATITGALELNVPVRALTPDQLTGRYDLVFLLTKQTVN
QAILTTLLPHLHADSIVCTLQNGIPEHAVAALVGAERTVGGAVGFGATWLKPGVSSLTSSYEAVRKFAFEIGEIDGVIRP
RLKVVQAYLECVGTTEIRSDLMGIRFSKLLMNATFSGMSAALGCTFGDVLDDARAMACLAFVADECIKVAHAHGVRLAEM
QGKDFERFELASAADIPSKMPLYREIWGPHAKLKASMLQDLEKRRDTEIGYINGLICAKGRERGVPTPFNDRIIELVAEA
QARRGVNDFGYLARFDDLLAAHVRDLPALAR
>Mature_351_residues
MRAAMVGAGSLGTIIGALMTRAGKQIDLVDSHQEHVDALNAFGATITGALELNVPVRALTPDQLTGRYDLVFLLTKQTVN
QAILTTLLPHLHADSIVCTLQNGIPEHAVAALVGAERTVGGAVGFGATWLKPGVSSLTSSYEAVRKFAFEIGEIDGVIRP
RLKVVQAYLECVGTTEIRSDLMGIRFSKLLMNATFSGMSAALGCTFGDVLDDARAMACLAFVADECIKVAHAHGVRLAEM
QGKDFERFELASAADIPSKMPLYREIWGPHAKLKASMLQDLEKRRDTEIGYINGLICAKGRERGVPTPFNDRIIELVAEA
QARRGVNDFGYLARFDDLLAAHVRDLPALAR

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 37886; Mature: 37886

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAMVGAGSLGTIIGALMTRAGKQIDLVDSHQEHVDALNAFGATITGALELNVPVRALT
CCCCEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCEEECC
PDQLTGRYDLVFLLTKQTVNQAILTTLLPHLHADSIVCTLQNGIPEHAVAALVGAERTVG
CHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHCC
GAVGFGATWLKPGVSSLTSSYEAVRKFAFEIGEIDGVIRPRLKVVQAYLECVGTTEIRSD
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LMGIRFSKLLMNATFSGMSAALGCTFGDVLDDARAMACLAFVADECIKVAHAHGVRLAEM
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
QGKDFERFELASAADIPSKMPLYREIWGPHAKLKASMLQDLEKRRDTEIGYINGLICAKG
CCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
RERGVPTPFNDRIIELVAEAQARRGVNDFGYLARFDDLLAAHVRDLPALAR
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHCCC
>Mature Secondary Structure
MRAAMVGAGSLGTIIGALMTRAGKQIDLVDSHQEHVDALNAFGATITGALELNVPVRALT
CCCCEECCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCEEEEEEECCCEEECC
PDQLTGRYDLVFLLTKQTVNQAILTTLLPHLHADSIVCTLQNGIPEHAVAALVGAERTVG
CHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHCC
GAVGFGATWLKPGVSSLTSSYEAVRKFAFEIGEIDGVIRPRLKVVQAYLECVGTTEIRSD
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LMGIRFSKLLMNATFSGMSAALGCTFGDVLDDARAMACLAFVADECIKVAHAHGVRLAEM
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
QGKDFERFELASAADIPSKMPLYREIWGPHAKLKASMLQDLEKRRDTEIGYINGLICAKG
CCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
RERGVPTPFNDRIIELVAEAQARRGVNDFGYLARFDDLLAAHVRDLPALAR
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]