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The map label for this gene is echA8 [H]

Identifier: 161524845

GI number: 161524845

Start: 1842286

End: 1843434

Strand: Reverse

Name: echA8 [H]

Synonym: Bmul_1672

Alternate gene names: 161524845

Gene position: 1843434-1842286 (Counterclockwise)

Preceding gene: 161524846

Following gene: 161524843

Centisome position: 53.46

GC content: 69.45

Gene sequence:

>1149_bases
ATGACCGACACCGCTTCCGCTTCTCCCGAATCCGCCCAGCCCGATGTGCGCGCGTATGTCGCGAACCGCATCGGCTTTCT
CGAACTGAACCGGCCGAAGGCGCTGAACGCGCTGTCCGTCGGGATGATCCGCACGATGCAGCAGGCGCTCGACGCGTGGC
GCGACGATCCGGACGTCGTCGCGGTCGTCGTGCACAGCCCGCATCCGCGCGCGTTCTGCGCGGGCGGCGACGTACGGTTT
TTCCACGACGCATGGCAGCGCGGCGATCGCGACGCGGTCGACACGTTCTTCATCGAGGAATACACGCTCAACCACGCGAT
CTTCACCTATCCGAAGCCGTACATCGCGCTGATGCACGGTGTCGTGATGGGCGGCGGGATGGGGATCTCGCAGGCCGCGC
GGCATACGGGCGGCCTGCGCGTCGTCACCGATTCGACGAAGATGGCGATGCCCGAAACCCGCATCGGGCTGTTTCCGGAC
GTCGGGATGAGCTGGTTCCTGGCCCGTACGCCGGGCATGATCGGCCGCTACCTCGCGGTGACGGGCGCGACGCTCGACGC
GTCCGGCGCGTTGGCCGCGCAGCTCGCCGACGTCTACGTGCCCGACGCCGCGTTGCCGGCGCTGATCGACGCGCTGAAGG
GCACGCGCTTCGACGACGGCGCGCAGGCCGTGGCGTGCGTCGCCGATGCGGCGGCCGCGCACAAGGTCGTACCGACGCCC
GATACCTCGGCGCTCGCCGACGCGCGCGCCGGCATCGATCGGCATTTCGCGCAGCCCGACATCGGCGCGATCGTCGCGTC
GCTCGAGGCGGAGCAGGACTGCGCGGCCGTCGACGGCTGGGTCGAGAAGGCGACGCATGCGATGCGCAGCGAGCTGTCGC
CGTTGTCGATGGCCGTGTCGCTCGAAGTCGTCGACCGCGCGCGCGGCGCGACGATGGCCGAATGCCTGCGGCGCGATCTC
GATCTCACACGCTCGACGTTCGCGCGCGGCGACGTGATCGAGGGCGTGCGTGCACTGATCGTCGACAAGGATCACCGGCC
GGCATGGCGGTTCAAGTCGATCGCCGACGTCGACCGCGCGGCCGTGCTCGCGATGTTCGACAGCCCTTGGACGCCCGACA
CGCATCCGCTGCGCCATCTGAAGGACTGA

Upstream 100 bases:

>100_bases
CGGCCTCGGCCTGATCATCTCGGGCGTCGTGGTGCTGAACCTGTTCTCGAAGATGCAGGCGCACTGAACGTGCGCGCGAT
TGCCCGATAGATAGACGCTC

Downstream 100 bases:

>100_bases
GCGCGCGGTGCCGCGCGAAGCGGCGTATCGAAATGAAAAGGCCGCCTGTCGATGCAGGCGGCCTTTTCGTTGGTGGGCGT
CGGAACGCGCGGTATGTGGT

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MTDTASASPESAQPDVRAYVANRIGFLELNRPKALNALSVGMIRTMQQALDAWRDDPDVVAVVVHSPHPRAFCAGGDVRF
FHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPD
VGMSWFLARTPGMIGRYLAVTGATLDASGALAAQLADVYVPDAALPALIDALKGTRFDDGAQAVACVADAAAAHKVVPTP
DTSALADARAGIDRHFAQPDIGAIVASLEAEQDCAAVDGWVEKATHAMRSELSPLSMAVSLEVVDRARGATMAECLRRDL
DLTRSTFARGDVIEGVRALIVDKDHRPAWRFKSIADVDRAAVLAMFDSPWTPDTHPLRHLKD

Sequences:

>Translated_382_residues
MTDTASASPESAQPDVRAYVANRIGFLELNRPKALNALSVGMIRTMQQALDAWRDDPDVVAVVVHSPHPRAFCAGGDVRF
FHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPD
VGMSWFLARTPGMIGRYLAVTGATLDASGALAAQLADVYVPDAALPALIDALKGTRFDDGAQAVACVADAAAAHKVVPTP
DTSALADARAGIDRHFAQPDIGAIVASLEAEQDCAAVDGWVEKATHAMRSELSPLSMAVSLEVVDRARGATMAECLRRDL
DLTRSTFARGDVIEGVRALIVDKDHRPAWRFKSIADVDRAAVLAMFDSPWTPDTHPLRHLKD
>Mature_381_residues
TDTASASPESAQPDVRAYVANRIGFLELNRPKALNALSVGMIRTMQQALDAWRDDPDVVAVVVHSPHPRAFCAGGDVRFF
HDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHGVVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPDV
GMSWFLARTPGMIGRYLAVTGATLDASGALAAQLADVYVPDAALPALIDALKGTRFDDGAQAVACVADAAAAHKVVPTPD
TSALADARAGIDRHFAQPDIGAIVASLEAEQDCAAVDGWVEKATHAMRSELSPLSMAVSLEVVDRARGATMAECLRRDLD
LTRSTFARGDVIEGVRALIVDKDHRPAWRFKSIADVDRAAVLAMFDSPWTPDTHPLRHLKD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=349, Percent_Identity=31.8051575931232, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI37594469, Length=301, Percent_Identity=31.8936877076412, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI194097323, Length=218, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144160, Length=356, Percent_Identity=37.9213483146067, Blast_Score=197, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI25144157, Length=356, Percent_Identity=37.9213483146067, Blast_Score=197, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6320241, Length=347, Percent_Identity=28.5302593659942, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28571730, Length=377, Percent_Identity=33.9522546419098, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28571729, Length=377, Percent_Identity=33.9522546419098, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24653139, Length=147, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 41142; Mature: 41011

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTASASPESAQPDVRAYVANRIGFLELNRPKALNALSVGMIRTMQQALDAWRDDPDVV
CCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
AVVVHSPHPRAFCAGGDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHG
EEEEECCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHH
VVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGMIGRYLAV
HHHCCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
TGATLDASGALAAQLADVYVPDAALPALIDALKGTRFDDGAQAVACVADAAAAHKVVPTP
CCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
DTSALADARAGIDRHFAQPDIGAIVASLEAEQDCAAVDGWVEKATHAMRSELSPLSMAVS
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEH
LEVVDRARGATMAECLRRDLDLTRSTFARGDVIEGVRALIVDKDHRPAWRFKSIADVDRA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHH
AVLAMFDSPWTPDTHPLRHLKD
HEEEEECCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TDTASASPESAQPDVRAYVANRIGFLELNRPKALNALSVGMIRTMQQALDAWRDDPDVV
CCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
AVVVHSPHPRAFCAGGDVRFFHDAWQRGDRDAVDTFFIEEYTLNHAIFTYPKPYIALMHG
EEEEECCCCCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHH
VVMGGGMGISQAARHTGGLRVVTDSTKMAMPETRIGLFPDVGMSWFLARTPGMIGRYLAV
HHHCCCCCHHHHHHHCCCEEEEECCCHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHH
TGATLDASGALAAQLADVYVPDAALPALIDALKGTRFDDGAQAVACVADAAAAHKVVPTP
CCCEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
DTSALADARAGIDRHFAQPDIGAIVASLEAEQDCAAVDGWVEKATHAMRSELSPLSMAVS
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHEEH
LEVVDRARGATMAECLRRDLDLTRSTFARGDVIEGVRALIVDKDHRPAWRFKSIADVDRA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCHHHHHHHHHHHH
AVLAMFDSPWTPDTHPLRHLKD
HEEEEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]