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The map label for this gene is rbsK [H]

Identifier: 161524800

GI number: 161524800

Start: 1802915

End: 1803847

Strand: Reverse

Name: rbsK [H]

Synonym: Bmul_1627

Alternate gene names: 161524800

Gene position: 1803847-1802915 (Counterclockwise)

Preceding gene: 161524801

Following gene: 161524799

Centisome position: 52.31

GC content: 75.78

Gene sequence:

>933_bases
ATGACGGCCGGCGCGGCAGCGCGTGCCGGCCGCGTCGCGGTGGTCGGCAGCCTCAACATGGATCTCGTCGTGCGCGCGCC
GCGGCTGCCGCTGCCGGGCGAGACGCTCGCGGGCCACGCGTTCGCGCAGGCGGCGGGCGGCAAGGGCGGCAACCAGGCCG
TCGCGGCGGCACGGCTCGGCGCGCAGGTCGCGATGATCGGCTGCGTCGGCGCGGATGCGCATGGCGCCGCGCTGCGCGCG
GGGCTCGAAGCCGAAGGGATCGACTGCGCGGGGCTCGCGACGAGCGCGTCCGCGCCGACCGGCGTCGCGCTGATCGTCGT
CGACGACGGAAGCCAGAACGCGATCGTGATCGTCGCGGGCGGCAACGGCGAAGTGACGCCGGAGACGGTCGCGCGGCACG
AGGCGACGTTCGCGTCCGCCGACGTGCTGATCTGCCAGCTCGAGACGCCGCCCGACACGGTCCGCGCGGCGCTTGCCGCC
GGACGCCGGCTCGGCCGCACGGTCGTGCTGAATCCGGCGCCGGCCGTCGCGCCGCTGCCGGCCGACTGGCTCGCATTGGT
CGACTATCTGATACCGAACGAACTGGAAGCCGCTGCGCTGACCGGCCGCCCGGTGCGCGACGCAGCGGACGCCGAAGTCG
CGGCGCGTGCGCTGCAGGCGCGCGGCGCGCGCAACGTGCTGATCACGCTCGGCGAACGCGGCGTGCTCGCGTTGACGGCC
GACGGCATCGCGCGACACTATCCGGCGCCGGTCGTGCGCGCGGTCGACACGACGGCCGCCGGCGACACGTTCATCGGCGG
TTTTGCCGCGCGGCTCGCGGCCGGCGCCGAGGTCGACGCGGCAATCCGTTTCGCACAGCGCGCGGCCGCGCTGTCGGTCA
CGCGGGCTGGCGCCCAGCCGTCCATCCCGACCCTCGCCGAACTCGGCGACTGA

Upstream 100 bases:

>100_bases
CGTCGGCGGCGCCGAGCCGGCGGCGCGTCGTGTCGCCGCGGCTCGTGCTGCGCGAATCGACGGCGATCTATCGCGAGCCG
GCCGCGTCCGGCTCCCGCGC

Downstream 100 bases:

>100_bases
CGCATTTCCCTCCCTGCGCGGCCGTTCCGTCGTGCGTCGGACGGCGGCCGCGATCCGCTTCCCGCATCGTCTTCGCCTCA
CCGCTGCCTTCGCACCTGCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTAGAAARAGRVAVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRA
GLEAEGIDCAGLATSASAPTGVALIVVDDGSQNAIVIVAGGNGEVTPETVARHEATFASADVLICQLETPPDTVRAALAA
GRRLGRTVVLNPAPAVAPLPADWLALVDYLIPNELEAAALTGRPVRDAADAEVAARALQARGARNVLITLGERGVLALTA
DGIARHYPAPVVRAVDTTAAGDTFIGGFAARLAAGAEVDAAIRFAQRAAALSVTRAGAQPSIPTLAELGD

Sequences:

>Translated_310_residues
MTAGAAARAGRVAVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRA
GLEAEGIDCAGLATSASAPTGVALIVVDDGSQNAIVIVAGGNGEVTPETVARHEATFASADVLICQLETPPDTVRAALAA
GRRLGRTVVLNPAPAVAPLPADWLALVDYLIPNELEAAALTGRPVRDAADAEVAARALQARGARNVLITLGERGVLALTA
DGIARHYPAPVVRAVDTTAAGDTFIGGFAARLAAGAEVDAAIRFAQRAAALSVTRAGAQPSIPTLAELGD
>Mature_309_residues
TAGAAARAGRVAVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLGAQVAMIGCVGADAHGAALRAG
LEAEGIDCAGLATSASAPTGVALIVVDDGSQNAIVIVAGGNGEVTPETVARHEATFASADVLICQLETPPDTVRAALAAG
RRLGRTVVLNPAPAVAPLPADWLALVDYLIPNELEAAALTGRPVRDAADAEVAARALQARGARNVLITLGERGVLALTAD
GIARHYPAPVVRAVDTTAAGDTFIGGFAARLAAGAEVDAAIRFAQRAAALSVTRAGAQPSIPTLAELGD

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=41.2162162162162, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=44.8504983388704, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87082343, Length=294, Percent_Identity=32.6530612244898, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87081971, Length=304, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=40.9836065573771, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319884, Length=336, Percent_Identity=32.7380952380952, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322565, Length=276, Percent_Identity=27.8985507246377, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=40.8637873754153, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=33.8926174496644, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30731; Mature: 30600

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGAAARAGRVAVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLG
CCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHC
AQVAMIGCVGADAHGAALRAGLEAEGIDCAGLATSASAPTGVALIVVDDGSQNAIVIVAG
CEEEEEEEECCCCCCHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEEC
GNGEVTPETVARHEATFASADVLICQLETPPDTVRAALAAGRRLGRTVVLNPAPAVAPLP
CCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCC
ADWLALVDYLIPNELEAAALTGRPVRDAADAEVAARALQARGARNVLITLGERGVLALTA
HHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEC
DGIARHYPAPVVRAVDTTAAGDTFIGGFAARLAAGAEVDAAIRFAQRAAALSVTRAGAQP
CCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCC
SIPTLAELGD
CCCCHHHCCC
>Mature Secondary Structure 
TAGAAARAGRVAVVGSLNMDLVVRAPRLPLPGETLAGHAFAQAAGGKGGNQAVAAARLG
CCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHCCHHHHHHCCCCCCCHHHHHHHHC
AQVAMIGCVGADAHGAALRAGLEAEGIDCAGLATSASAPTGVALIVVDDGSQNAIVIVAG
CEEEEEEEECCCCCCHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEEEC
GNGEVTPETVARHEATFASADVLICQLETPPDTVRAALAAGRRLGRTVVLNPAPAVAPLP
CCCCCCHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCCC
ADWLALVDYLIPNELEAAALTGRPVRDAADAEVAARALQARGARNVLITLGERGVLALTA
HHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEC
DGIARHYPAPVVRAVDTTAAGDTFIGGFAARLAAGAEVDAAIRFAQRAAALSVTRAGAQP
CCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCC
SIPTLAELGD
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]