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The map label for this gene is fhuB [H]

Identifier: 161524775

GI number: 161524775

Start: 1771386

End: 1773476

Strand: Reverse

Name: fhuB [H]

Synonym: Bmul_1602

Alternate gene names: 161524775

Gene position: 1773476-1771386 (Counterclockwise)

Preceding gene: 161524776

Following gene: 161524774

Centisome position: 51.43

GC content: 74.84

Gene sequence:

>2091_bases
ATGACGACGACGGTCGCGATACGCAAGCGCGCGCCTGCCGCGCCCGCCGGAACCGGTCGCCGCGCCGGCCGGATCGCGAT
CGGCGCGATCGTGCTGATCGCGCTCGTCGCGGCGATGCGTGTCGCACCCGATCTGCTCACGTGGTGGCGCGCCGCGCCCG
GCAGCGACGCGGCCGCGCTCGCGCACGTGTTCCTGTTCGATCTCGGTTTGCCGCGTATCGCGGCCGCGCTCGTCGCCGGC
GGCTGCCTCGGCATCGCGGGCGCGCTGTTCCAGTCGCTGACGCGCAATCCGCTCGCGTCGCCGGACCTGCTCGGCGTGAC
GGGCGGCGCGCAGCTCGGGCTGCTCGCGTCGATGCTCGTGCCCGCGCTCGCGGGCGTCGCGTCGGTGCCGCTGCTGTTCG
TCTGCGGACTCGCGGCGGCGGCTTGCGCGATCGCGGCGGCCGGCGGCTGGCGCGCGACGCCGCTACGCCTCGTGCTCGCG
GGCAGCGTCTGCATGCTGCTGTTCGCCGCGTTGTCGACGCTCGTGCTCGCGTTTTTCGAGCAGAACATCGCGGGCGCCGC
GCTGTGGGCGAACGGTAGCCTGTATCAGCCGGGTGCGGCAGGGCTCGCGCTCGCGGCGCGCTGGCTCGTCGCACCGCTCG
TCGCCTTGCCGTTCGTGATGCGGCCGCTCGATCCGCTCGCGCTCGGCGACGACGCGGCGGCCGCGGCCGGCGTGCGCATC
GACGCGACGCGGCTCGCCGCGACGGTCGTGGCAGTCGCGTTCACGAGCGTCGCGGTCAGCATCGCGGGGCCGCTGTCGTA
TGTCGGCCTCGTCGCGCCGAACCTGATTCGCCAGATCCGCGGTGCGCGCGCGGCGCGGCTCGGTGCGCTCGTCCCGCTGT
CCGCACTCGCCGGCGCAGCGCTCGTGCTCGTCACCGACAGCGCGGTGCTCGCGTCGGGACTCGATGCGACGCTGTCGACC
GGCGTCGCGATCGCACTGGTCGGCACGCCGCTGATGCTGATGATGATCCGGCGCGGCGCCGCGTGGTCGGGCGTGCTGCA
TGGGCCGCCCGAGCGCGCGGCCGGCGGCCGGTCGACGCGCATCGTCGGCTGGCTCGAACGGCTCGGCTGGCCGCTGCGCG
CCGCGCTGTTCGCCGCGGTCGCGCTCGTCGTCGTATACGTCGGCGTGTCGTCCGGTCCCGAATGGCTCGCGCCCGCGCGC
TGGTTCGCCGCGTTGTCCGGGCACGATCCGCTCGCGCGCATGCTGCTCGATCTGCGCATGCCGCGGCTGCTGTGCGCGCT
GCTTGCCGGCGCGCTGCTCGCGGTGAGCGGCGTCGCGATGCAGAGCGTCGTGCGCAATCCGCTCGCGGGGCCGGAGGTGC
TCGGCGTCACGCAGGGCGCGGGGCTCGTCACGCTGTTCGCGCTGTCCGCGTGGCCGTTGATCGGCCACGTCGGGCTCGCG
GCCGCCGCGCTGATCGGCGGCGGGCTGTCGCTTGCGATCACGCTCGCGCTCAATCATCGCCATCGCTATGCGCCGCTCGC
GGTCGCGCTGACCGGCATCGTGACGGGCGCGTTGTGGACCACGCTCGCGCAATGGCTGATCACGCAGGAAAGCGTGCAGC
CGGCGCGCTTCGTCGTCTGGCTCGTCGGCGGCACGTACGGCCGCAGCTGGGGCGAGGTGTCGATGCTCGTGCCGTGGTGC
GTGCTCGCGGTGCCTGTCTTCGCGTGGCTCGCGAAGCCGCTCGACATGCTTGCGCTCGGCGACGACCAGGCTGCCGCGCT
CGGCCTGCCGGTCGCGATGCTGCGGCCGCTCGCGCTGACGATCGCGACGCTCGCCGCGTGCGCGGCCGTCGCGGCGGTCG
GGCCGATCGGCTTCATCGGGCTGATGGCGCCGCATGTCGCGACGATGCTCGGCGCGCGCCGTCATCGCACGCGGCTGTGG
CTCGCGGCCGCGTGCGGTGCGCTGATTCTCACGGCCGCCGATCTCGCGGCGCGCACGCTCGTCGCGCCGCGCGAAGTGCC
GGCCGGCGTGCTGACCGCGCTGATCGGCGCGCCGTACCTGCTCGGGCTGCTGATTCTCGAGGCGCGCCGCGCGCGGCGCG
CGGCGCGATGA

Upstream 100 bases:

>100_bases
AGCTCGCGCATCCGCAGACGGGCGCGCCGCTGTGCGTGCCGGCGTACGGGCCGGCGACGGCCGCGCCCGAGGCCGCGCAC
GCGTCGGACCGGGATCTCGC

Downstream 100 bases:

>100_bases
CCGGGCAGCGCGACGGCGCGCGCGCGACGCGCTTCTCGACCTTCGCGCCCGAGCCGTTCGCAGCGCATCTCGACGTCGTG
TGGCTCGGCATGCCGGACGA

Product: iron-hydroxamate transporter permease subunit

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Ferrichrome uptake protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MTTTVAIRKRAPAAPAGTGRRAGRIAIGAIVLIALVAAMRVAPDLLTWWRAAPGSDAAALAHVFLFDLGLPRIAAALVAG
GCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLASMLVPALAGVASVPLLFVCGLAAAACAIAAAGGWRATPLRLVLA
GSVCMLLFAALSTLVLAFFEQNIAGAALWANGSLYQPGAAGLALAARWLVAPLVALPFVMRPLDPLALGDDAAAAAGVRI
DATRLAATVVAVAFTSVAVSIAGPLSYVGLVAPNLIRQIRGARAARLGALVPLSALAGAALVLVTDSAVLASGLDATLST
GVAIALVGTPLMLMMIRRGAAWSGVLHGPPERAAGGRSTRIVGWLERLGWPLRAALFAAVALVVVYVGVSSGPEWLAPAR
WFAALSGHDPLARMLLDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSAWPLIGHVGLA
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVTGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLVPWC
VLAVPVFAWLAKPLDMLALGDDQAAALGLPVAMLRPLALTIATLAACAAVAAVGPIGFIGLMAPHVATMLGARRHRTRLW
LAAACGALILTAADLAARTLVAPREVPAGVLTALIGAPYLLGLLILEARRARRAAR

Sequences:

>Translated_696_residues
MTTTVAIRKRAPAAPAGTGRRAGRIAIGAIVLIALVAAMRVAPDLLTWWRAAPGSDAAALAHVFLFDLGLPRIAAALVAG
GCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLASMLVPALAGVASVPLLFVCGLAAAACAIAAAGGWRATPLRLVLA
GSVCMLLFAALSTLVLAFFEQNIAGAALWANGSLYQPGAAGLALAARWLVAPLVALPFVMRPLDPLALGDDAAAAAGVRI
DATRLAATVVAVAFTSVAVSIAGPLSYVGLVAPNLIRQIRGARAARLGALVPLSALAGAALVLVTDSAVLASGLDATLST
GVAIALVGTPLMLMMIRRGAAWSGVLHGPPERAAGGRSTRIVGWLERLGWPLRAALFAAVALVVVYVGVSSGPEWLAPAR
WFAALSGHDPLARMLLDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSAWPLIGHVGLA
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVTGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLVPWC
VLAVPVFAWLAKPLDMLALGDDQAAALGLPVAMLRPLALTIATLAACAAVAAVGPIGFIGLMAPHVATMLGARRHRTRLW
LAAACGALILTAADLAARTLVAPREVPAGVLTALIGAPYLLGLLILEARRARRAAR
>Mature_695_residues
TTTVAIRKRAPAAPAGTGRRAGRIAIGAIVLIALVAAMRVAPDLLTWWRAAPGSDAAALAHVFLFDLGLPRIAAALVAGG
CLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLASMLVPALAGVASVPLLFVCGLAAAACAIAAAGGWRATPLRLVLAG
SVCMLLFAALSTLVLAFFEQNIAGAALWANGSLYQPGAAGLALAARWLVAPLVALPFVMRPLDPLALGDDAAAAAGVRID
ATRLAATVVAVAFTSVAVSIAGPLSYVGLVAPNLIRQIRGARAARLGALVPLSALAGAALVLVTDSAVLASGLDATLSTG
VAIALVGTPLMLMMIRRGAAWSGVLHGPPERAAGGRSTRIVGWLERLGWPLRAALFAAVALVVVYVGVSSGPEWLAPARW
FAALSGHDPLARMLLDLRMPRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSAWPLIGHVGLAA
AALIGGGLSLAITLALNHRHRYAPLAVALTGIVTGALWTTLAQWLITQESVQPARFVVWLVGGTYGRSWGEVSMLVPWCV
LAVPVFAWLAKPLDMLALGDDQAAALGLPVAMLRPLALTIATLAACAAVAAVGPIGFIGLMAPHVATMLGARRHRTRLWL
AAACGALILTAADLAARTLVAPREVPAGVLTALIGAPYLLGLLILEARRARRAAR

Specific function: Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786347, Length=649, Percent_Identity=31.2788906009245, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1790740, Length=315, Percent_Identity=40, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI1788004, Length=310, Percent_Identity=35.1612903225806, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1786804, Length=309, Percent_Identity=36.5695792880259, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=282, Percent_Identity=35.8156028368794, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=33.1034482758621, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 70747; Mature: 70616

Theoretical pI: Translated: 11.77; Mature: 11.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTVAIRKRAPAAPAGTGRRAGRIAIGAIVLIALVAAMRVAPDLLTWWRAAPGSDAAAL
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AHVFLFDLGLPRIAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLASMLV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHH
PALAGVASVPLLFVCGLAAAACAIAAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNIAGAALWANGSLYQPGAAGLALAARWLVAPLVALPFVMRPLDPLALGDDAAAAAGVRI
HCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
DATRLAATVVAVAFTSVAVSIAGPLSYVGLVAPNLIRQIRGARAARLGALVPLSALAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LVLVTDSAVLASGLDATLSTGVAIALVGTPLMLMMIRRGAAWSGVLHGPPERAAGGRSTR
EEEEECCHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
IVGWLERLGWPLRAALFAAVALVVVYVGVSSGPEWLAPARWFAALSGHDPLARMLLDLRM
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
PRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSAWPLIGHVGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVTGALWTTLAQWLITQESVQPARFVVW
HHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
LVGGTYGRSWGEVSMLVPWCVLAVPVFAWLAKPLDMLALGDDQAAALGLPVAMLRPLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHHH
IATLAACAAVAAVGPIGFIGLMAPHVATMLGARRHRTRLWLAAACGALILTAADLAARTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPREVPAGVLTALIGAPYLLGLLILEARRARRAAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTVAIRKRAPAAPAGTGRRAGRIAIGAIVLIALVAAMRVAPDLLTWWRAAPGSDAAAL
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AHVFLFDLGLPRIAAALVAGGCLGIAGALFQSLTRNPLASPDLLGVTGGAQLGLLASMLV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHH
PALAGVASVPLLFVCGLAAAACAIAAAGGWRATPLRLVLAGSVCMLLFAALSTLVLAFFE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNIAGAALWANGSLYQPGAAGLALAARWLVAPLVALPFVMRPLDPLALGDDAAAAAGVRI
HCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEE
DATRLAATVVAVAFTSVAVSIAGPLSYVGLVAPNLIRQIRGARAARLGALVPLSALAGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LVLVTDSAVLASGLDATLSTGVAIALVGTPLMLMMIRRGAAWSGVLHGPPERAAGGRSTR
EEEEECCHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
IVGWLERLGWPLRAALFAAVALVVVYVGVSSGPEWLAPARWFAALSGHDPLARMLLDLRM
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
PRLLCALLAGALLAVSGVAMQSVVRNPLAGPEVLGVTQGAGLVTLFALSAWPLIGHVGLA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
AAALIGGGLSLAITLALNHRHRYAPLAVALTGIVTGALWTTLAQWLITQESVQPARFVVW
HHHHHCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
LVGGTYGRSWGEVSMLVPWCVLAVPVFAWLAKPLDMLALGDDQAAALGLPVAMLRPLALT
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHCCCHHHHHHHHHH
IATLAACAAVAAVGPIGFIGLMAPHVATMLGARRHRTRLWLAAACGALILTAADLAARTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAPREVPAGVLTALIGAPYLLGLLILEARRARRAAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258 [H]