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The map label for this gene is fecB [H]

Identifier: 161524773

GI number: 161524773

Start: 1769558

End: 1770592

Strand: Reverse

Name: fecB [H]

Synonym: Bmul_1600

Alternate gene names: 161524773

Gene position: 1770592-1769558 (Counterclockwise)

Preceding gene: 161524774

Following gene: 161524771

Centisome position: 51.34

GC content: 70.82

Gene sequence:

>1035_bases
GTGACGGACGCGGGGCGCCGACGCGCGCTCGCGCAACTCGCCGCCAGCGCGTGCTGCGGCGCGTTCGCTGCGTTCGGTGG
ATTCGGCGTATTCGGTGCGCCTGCGATGGCGGCCGATGCGCCGCCCGCATCGCGCCGCACGCTGTCGCTCGCCGGCAATC
CGGTCGTGTCGCAGGCGAGCGCGACGATGCCCGTGCGGCCGCAGCGCGTGGTCGCGCTCGACTTCATGTTCGCGGAAAGC
GTCGTCGCGCTCGATCTGATCCCGGTCGGGATGGCCGACACGGCGTTCTATCCGGGCTGGCTCGGCTACGAGAGCGCGCG
TATCGCGCACGTCACCGACATCGGGTCGCGGCAGGAGCCCGGCCTCGAGGCGATCGCGGCCGTCAGGCCCGACCTGATCA
TCGGCGTCGGCTTCCGGCATGCGCCGATCTTCGACGCGCTCGACCGCATCGCGCCGACGATCCTGTTCCAGTTCAGCCCG
AACGTGTCGGAAGGCGGCGTGCCCGTCACGCAGCTCGACTGGATGCGGCAGATCTTCAGGACGATCGGCACGGTCACGGG
TCGCGACGCGCGTGCGCGCGCGGTCGAAGCGCAACTCGATGCGGGGCTCGCGCGCAACGCGGCGCGTCTGTCGGCGGCCG
GCCGCGCGGGCGAGCGGATCGCGCTGCTGCAGGAGCTGGGCCTGCCGGACCGCTACTGGGCGTACACCGGCAACAGTACC
GCGGCCGGGCTCGCGCGTGCGCTCGGTCTCGTCCCGTGGCCGAAAAAGCCGACACGCGAAGGGACGATCTATGTGACGTC
GGCCGATCTGCTGACGCAGCGCGATCTGGCGATCCTGTTCGTGACCGCGACCGCGCTCGACGTGCCGCTGTCCGCGAAGC
TCGATTCGCCGGTGTGGCGTTTCGTGCCGGCATGGCGCGCGCATCGGATCGCGATGATCGAGCGCAATATCTGGGGTTTC
GGCGGGCCGATGTCGGCGCTGAAACTCGCCGACGTGATGACCGATACGATGCTGACGCTGCCGGCCGTGCGCTGA

Upstream 100 bases:

>100_bases
GCCTGCGCTACGAAATTCCTGGAGAAACGCAACTGTGTGGAAGCTGTCCTCTGCTGCTGACGATGGACGACGCGGCGCTG
GCCGAGCAGGACGCGACCCG

Downstream 100 bases:

>100_bases
GCGCGTTTCGCCGCGTCGTTCTCTTTTATCGGTCGTTCACAGAGGCGCCGGCCGTCGCGATCGCGACAGGCCGGCGCCTT
GCGTTTACGTGCTCAGCGCA

Product: periplasmic binding protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate-binding periplasmic protein [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTDAGRRRALAQLAASACCGAFAAFGGFGVFGAPAMAADAPPASRRTLSLAGNPVVSQASATMPVRPQRVVALDFMFAES
VVALDLIPVGMADTAFYPGWLGYESARIAHVTDIGSRQEPGLEAIAAVRPDLIIGVGFRHAPIFDALDRIAPTILFQFSP
NVSEGGVPVTQLDWMRQIFRTIGTVTGRDARARAVEAQLDAGLARNAARLSAAGRAGERIALLQELGLPDRYWAYTGNST
AAGLARALGLVPWPKKPTREGTIYVTSADLLTQRDLAILFVTATALDVPLSAKLDSPVWRFVPAWRAHRIAMIERNIWGF
GGPMSALKLADVMTDTMLTLPAVR

Sequences:

>Translated_344_residues
MTDAGRRRALAQLAASACCGAFAAFGGFGVFGAPAMAADAPPASRRTLSLAGNPVVSQASATMPVRPQRVVALDFMFAES
VVALDLIPVGMADTAFYPGWLGYESARIAHVTDIGSRQEPGLEAIAAVRPDLIIGVGFRHAPIFDALDRIAPTILFQFSP
NVSEGGVPVTQLDWMRQIFRTIGTVTGRDARARAVEAQLDAGLARNAARLSAAGRAGERIALLQELGLPDRYWAYTGNST
AAGLARALGLVPWPKKPTREGTIYVTSADLLTQRDLAILFVTATALDVPLSAKLDSPVWRFVPAWRAHRIAMIERNIWGF
GGPMSALKLADVMTDTMLTLPAVR
>Mature_343_residues
TDAGRRRALAQLAASACCGAFAAFGGFGVFGAPAMAADAPPASRRTLSLAGNPVVSQASATMPVRPQRVVALDFMFAESV
VALDLIPVGMADTAFYPGWLGYESARIAHVTDIGSRQEPGLEAIAAVRPDLIIGVGFRHAPIFDALDRIAPTILFQFSPN
VSEGGVPVTQLDWMRQIFRTIGTVTGRDARARAVEAQLDAGLARNAARLSAAGRAGERIALLQELGLPDRYWAYTGNSTA
AGLARALGLVPWPKKPTREGTIYVTSADLLTQRDLAILFVTATALDVPLSAKLDSPVWRFVPAWRAHRIAMIERNIWGFG
GPMSALKLADVMTDTMLTLPAVR

Specific function: Binds citrate-dependent Fe(3+); part of the binding- protein-dependent transport system for uptake of citrate-dependent Fe(3+) [H]

COG id: COG0614

COG function: function code P; ABC-type Fe3+-hydroxamate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082411, Length=264, Percent_Identity=26.1363636363636, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786346, Length=304, Percent_Identity=25.9868421052632, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 36651; Mature: 36520

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAGRRRALAQLAASACCGAFAAFGGFGVFGAPAMAADAPPASRRTLSLAGNPVVSQAS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
ATMPVRPQRVVALDFMFAESVVALDLIPVGMADTAFYPGWLGYESARIAHVTDIGSRQEP
CCCCCCCCCEEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
GLEAIAAVRPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVSEGGVPVTQLDWMRQIFR
CHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHH
TIGTVTGRDARARAVEAQLDAGLARNAARLSAAGRAGERIALLQELGLPDRYWAYTGNST
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCH
AAGLARALGLVPWPKKPTREGTIYVTSADLLTQRDLAILFVTATALDVPLSAKLDSPVWR
HHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEHHHCCCCCCCCCCCHHH
FVPAWRAHRIAMIERNIWGFGGPMSALKLADVMTDTMLTLPAVR
HHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDAGRRRALAQLAASACCGAFAAFGGFGVFGAPAMAADAPPASRRTLSLAGNPVVSQAS
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
ATMPVRPQRVVALDFMFAESVVALDLIPVGMADTAFYPGWLGYESARIAHVTDIGSRQEP
CCCCCCCCCEEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCC
GLEAIAAVRPDLIIGVGFRHAPIFDALDRIAPTILFQFSPNVSEGGVPVTQLDWMRQIFR
CHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHH
TIGTVTGRDARARAVEAQLDAGLARNAARLSAAGRAGERIALLQELGLPDRYWAYTGNST
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCH
AAGLARALGLVPWPKKPTREGTIYVTSADLLTQRDLAILFVTATALDVPLSAKLDSPVWR
HHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEHHHCCCCCCCCCCCHHH
FVPAWRAHRIAMIERNIWGFGGPMSALKLADVMTDTMLTLPAVR
HHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]