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The map label for this gene is yphC [C]

Identifier: 161524675

GI number: 161524675

Start: 1654593

End: 1655642

Strand: Reverse

Name: yphC [C]

Synonym: Bmul_1502

Alternate gene names: 161524675

Gene position: 1655642-1654593 (Counterclockwise)

Preceding gene: 161524677

Following gene: 161524671

Centisome position: 48.01

GC content: 68.38

Gene sequence:

>1050_bases
ATGGTGAAAGCAGTCGTTTACGAAGCGTTCGGCGCCGCGCCGCGCGTGATGCAGGTCGCGGACCCGACGCCCGCGCCGGA
CGGCGTCGTGATCGAGGTGAAGGCGACCGGCGTCTGCCGCAGCGACTGGCACGGCTGGATGGGGCACGATCCGGACATCG
TGCTGCCGCACGTGCCGGGACACGAACTGGCGGGCGTGGTCGTCGCGACCGGTGCGGACGTCACGCGCTGGAAGGCCGGC
GACCGCGTGACCGTGCCGTTCGTCGCCGGCTGCGGCCGCTGCCCCGAGTGTCATTCCGGCAACCAGCAAGTATGCGAGCG
GCAATTTCAGCCGGGCTTCACGCACTGGGGTTCGTTCGCCGAATTCGTCGGCATCCATCATGCGGACCTGAACCTCGTGC
GGCTGCCCGACTCGCTCGATTTTCCGACCGCGGCAAGCCTCGGCTGCCGGTTCGTCACGTCGTTTCGTGCGGTCGTCGAT
CAGGGGCGCACGTCGGCCGGCGAATGGGTCGCGGTGCACGGCTGCGGCGGCGTCGGATTGTCGGCGATCATGATCGCGAA
CGCGATCGGCGCGAATGTCGTCGCAGTCGACATTTCGGCGGCCGCGCTTGCGCGCGCGCGCGCGGTGGGTGCGGCCGCGA
CCGTCGATGCGTCGCAGGTCGCCGACGTCGTCGATGCGGTGAAGGACATTACCGGCGGCGGCGCGCACGTGTCGCTCGAT
GCGCTGGGCCACCCGAGCACCTGCTTCAACTCGATTGCAAACTTGCGTCGCCGCGGCCGGCACGTGCAGGTCGGGCTGAT
GCTCGGCGAGCATGCGACGCCGGCGGTGCCGATGAGCAAGGTGATCGCCCACGAGCTCGAGATTCTCGGCAGCCACGGGA
TGCAGGCGCATCGCTACGATGCCATGCTCGATATGGTGCGCGCCGGCAAGCTGGCGCCGAGCCGGTTGATCGGCAAGGAA
ACCAGCCTCGGCGAGTCGGTCGAGGCGCTGATGAACATGAACCGGTTCGAAGGCGCCGGTGTGACGGTCGTGACGGATTT
TTCGCACTGA

Upstream 100 bases:

>100_bases
CGCAAGGCTAGCCCAAAAGAGCCCGCGCCTCAATCGAAAAACGAAAGGTAAATCCGATATTGCGCGGTTATAGTGAAAGA
GTCATTCGCAACAGGAGGAA

Downstream 100 bases:

>100_bases
AAGCGGATGCCGGGCGCGCGATCGCGTCGCCCGGCATCGCGTTGCGCTCTCCGTTCGCGCGCGACGGTTCGACGCACACG
AACGGTGCGCGCTGCGGCTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVKAVVYEAFGAAPRVMQVADPTPAPDGVVIEVKATGVCRSDWHGWMGHDPDIVLPHVPGHELAGVVVATGADVTRWKAG
DRVTVPFVAGCGRCPECHSGNQQVCERQFQPGFTHWGSFAEFVGIHHADLNLVRLPDSLDFPTAASLGCRFVTSFRAVVD
QGRTSAGEWVAVHGCGGVGLSAIMIANAIGANVVAVDISAAALARARAVGAAATVDASQVADVVDAVKDITGGGAHVSLD
ALGHPSTCFNSIANLRRRGRHVQVGLMLGEHATPAVPMSKVIAHELEILGSHGMQAHRYDAMLDMVRAGKLAPSRLIGKE
TSLGESVEALMNMNRFEGAGVTVVTDFSH

Sequences:

>Translated_349_residues
MVKAVVYEAFGAAPRVMQVADPTPAPDGVVIEVKATGVCRSDWHGWMGHDPDIVLPHVPGHELAGVVVATGADVTRWKAG
DRVTVPFVAGCGRCPECHSGNQQVCERQFQPGFTHWGSFAEFVGIHHADLNLVRLPDSLDFPTAASLGCRFVTSFRAVVD
QGRTSAGEWVAVHGCGGVGLSAIMIANAIGANVVAVDISAAALARARAVGAAATVDASQVADVVDAVKDITGGGAHVSLD
ALGHPSTCFNSIANLRRRGRHVQVGLMLGEHATPAVPMSKVIAHELEILGSHGMQAHRYDAMLDMVRAGKLAPSRLIGKE
TSLGESVEALMNMNRFEGAGVTVVTDFSH
>Mature_349_residues
MVKAVVYEAFGAAPRVMQVADPTPAPDGVVIEVKATGVCRSDWHGWMGHDPDIVLPHVPGHELAGVVVATGADVTRWKAG
DRVTVPFVAGCGRCPECHSGNQQVCERQFQPGFTHWGSFAEFVGIHHADLNLVRLPDSLDFPTAASLGCRFVTSFRAVVD
QGRTSAGEWVAVHGCGGVGLSAIMIANAIGANVVAVDISAAALARARAVGAAATVDASQVADVVDAVKDITGGGAHVSLD
ALGHPSTCFNSIANLRRRGRHVQVGLMLGEHATPAVPMSKVIAHELEILGSHGMQAHRYDAMLDMVRAGKLAPSRLIGKE
TSLGESVEALMNMNRFEGAGVTVVTDFSH

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565154, Length=264, Percent_Identity=29.1666666666667, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4501933, Length=273, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI71565152, Length=271, Percent_Identity=27.3062730627306, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI71743840, Length=266, Percent_Identity=26.6917293233083, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI262073058, Length=266, Percent_Identity=26.6917293233083, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI34577061, Length=252, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI156523966, Length=265, Percent_Identity=26.7924528301887, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4501939, Length=265, Percent_Identity=26.7924528301887, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4501929, Length=273, Percent_Identity=29.6703296703297, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI156627571, Length=359, Percent_Identity=24.7910863509749, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87082125, Length=329, Percent_Identity=29.7872340425532, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI226510992, Length=321, Percent_Identity=31.4641744548287, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87081918, Length=291, Percent_Identity=31.6151202749141, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787863, Length=331, Percent_Identity=25.9818731117825, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788075, Length=357, Percent_Identity=25.7703081232493, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788073, Length=350, Percent_Identity=23.1428571428571, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786825, Length=274, Percent_Identity=28.8321167883212, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790045, Length=306, Percent_Identity=27.1241830065359, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786518, Length=272, Percent_Identity=28.6764705882353, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786552, Length=265, Percent_Identity=28.6792452830189, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788407, Length=271, Percent_Identity=26.5682656826568, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790718, Length=325, Percent_Identity=25.2307692307692, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082401, Length=335, Percent_Identity=27.1641791044776, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71988145, Length=268, Percent_Identity=30.5970149253731, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562584, Length=352, Percent_Identity=28.9772727272727, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17562582, Length=266, Percent_Identity=31.5789473684211, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17562876, Length=339, Percent_Identity=29.2035398230088, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=333, Percent_Identity=28.5285285285285, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71997431, Length=228, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17565904, Length=207, Percent_Identity=29.4685990338164, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=228, Percent_Identity=28.9473684210526, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=347, Percent_Identity=29.971181556196, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=30.3834808259587, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6323961, Length=347, Percent_Identity=30.835734870317, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323729, Length=324, Percent_Identity=29.9382716049383, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320033, Length=270, Percent_Identity=29.6296296296296, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319955, Length=325, Percent_Identity=28.6153846153846, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=325, Percent_Identity=28.6153846153846, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=321, Percent_Identity=28.0373831775701, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319257, Length=347, Percent_Identity=25.9365994236311, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=202, Percent_Identity=32.1782178217822, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323980, Length=201, Percent_Identity=30.8457711442786, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319258, Length=321, Percent_Identity=25.2336448598131, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17737895, Length=270, Percent_Identity=29.2592592592593, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17137530, Length=344, Percent_Identity=28.4883720930233, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737897, Length=347, Percent_Identity=28.2420749279539, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36538; Mature: 36538

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAVVYEAFGAAPRVMQVADPTPAPDGVVIEVKATGVCRSDWHGWMGHDPDIVLPHVPG
CCCEEEEHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCC
HELAGVVVATGADVTRWKAGDRVTVPFVAGCGRCPECHSGNQQVCERQFQPGFTHWGSFA
CHHCEEEEECCCCEEEECCCCEEEEEHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
EFVGIHHADLNLVRLPDSLDFPTAASLGCRFVTSFRAVVDQGRTSAGEWVAVHGCGGVGL
HHHHEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
SAIMIANAIGANVVAVDISAAALARARAVGAAATVDASQVADVVDAVKDITGGGAHVSLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEE
ALGHPSTCFNSIANLRRRGRHVQVGLMLGEHATPAVPMSKVIAHELEILGSHGMQAHRYD
CCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
AMLDMVRAGKLAPSRLIGKETSLGESVEALMNMNRFEGAGVTVVTDFSH
HHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MVKAVVYEAFGAAPRVMQVADPTPAPDGVVIEVKATGVCRSDWHGWMGHDPDIVLPHVPG
CCCEEEEHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCC
HELAGVVVATGADVTRWKAGDRVTVPFVAGCGRCPECHSGNQQVCERQFQPGFTHWGSFA
CHHCEEEEECCCCEEEECCCCEEEEEHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHH
EFVGIHHADLNLVRLPDSLDFPTAASLGCRFVTSFRAVVDQGRTSAGEWVAVHGCGGVGL
HHHHEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
SAIMIANAIGANVVAVDISAAALARARAVGAAATVDASQVADVVDAVKDITGGGAHVSLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCEEEEE
ALGHPSTCFNSIANLRRRGRHVQVGLMLGEHATPAVPMSKVIAHELEILGSHGMQAHRYD
CCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
AMLDMVRAGKLAPSRLIGKETSLGESVEALMNMNRFEGAGVTVVTDFSH
HHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]