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The map label for this gene is emrY [H]

Identifier: 161524615

GI number: 161524615

Start: 1586967

End: 1588523

Strand: Reverse

Name: emrY [H]

Synonym: Bmul_1442

Alternate gene names: 161524615

Gene position: 1588523-1586967 (Counterclockwise)

Preceding gene: 161524616

Following gene: 161524614

Centisome position: 46.06

GC content: 67.44

Gene sequence:

>1557_bases
ATGAACGTCACGTCGGGGCGCCCGCCGCTGTGGAGCCGCGCGAACCTGCGCGCGGACCTGTTCCCGTGGGCGCTTGCGCT
CGTCACCGGGCTCGACTACTTCGACAACGCGATCTTCTCGTTCTTCGCGAGCTATATCGCGGGCGGCATCAACGCGTCGC
CGGACGAACTCGTGTGGGCGTCGAGCGCATATGCGGTCACGGCCGTGCTCGGCATCCTGCAGCAGCAATGGTGGGTCGAC
CGCCTCGGGCATCGCCGCTACGTTGCCGGCTGCATGCTGATGTTCTCGTTCGGCGCGATCGCGGCCGCGCTCGCCGATAC
GTCGCTCGAACTCGCCTTCGCGCGCGGCTTCCAGGGCTACTTCATTGGCCCGATGATGGGCGCGTGCCGGATCCTGATCC
AGATCAGCTTCAAGCCGCAGACGCGGCCGCCCGCCACGCGCGCGTTCCTGATCATGATCCTGCTCGGCAGCGCGCTCGCG
CCGATCGTCGGCGGGCTGTTCGTCGCGTATTCGACGTGGCGCGCGCTGTTCGCGTGCACGGCGCCGGCCGGCATCGTGTT
CGCGATCCTCGCGCTGCTCACGCTGCCCGACTCGGGCCGCACGCCGGACGACGAACGCGGCTCCGGACACTTCTGGCCGT
ACGTCGTGTTCGCGCTCGCGCAAGGCGCGCTGCAGATCGTGATGCAGCAGGTGCACTACCAGCTGTACAGCGGCTCGCCG
ATGCTGATCGGCCTGACCGCCGCGGGGCTCGGCGCGCTCGCCTGGTTCGCGTATCACCAGTGGAATCACCCGACGCCGCT
CGTCCGGCTGCACGCGCTGCGCGAGCGCACGTTCCAGATCGGCCTGCTGCTCTACATGTTCTATTACTACGAGTCGACGG
GCTTCAGCTATCTGACGTCGCGCTTTCTCGAATCGGGGCTCGGCTATCCGGTCGAGAACGCCGGGCGGCTCGTCGGCACG
ATGTCGCTGATTTCGGCCACCGCGCTGTTCGCGTACCTGCGCTATGCGAAGCACGTCGCGCACAAGAAATGGTTCGTCGT
GCCGGGCTTCGCGATCGCGATCGTCGCGACGCTATGGATGACGCGGCTCACGCCGCAAGTCGGCGAGGCCGCGCTCGTCG
TGCCGCTGCTGCTGCGCGGCCTGCTGCTGCTGTTCATCGTGCTGCCGGTCGCGAACCTCACGTTCCGGATCTTCGCGATC
GACGAGTACACGCACGGCTATCGGCTGAAGAACATCGTGCGGCAGCTGACGATCACGTTCGCGACGTCGTCGGTGATCAT
CGTCGAGCAGCATCGGCTCGCGGTGCACCAGACGAGGCTCGTCGAACGCGCGAACGTGTTCGACCCGCTGTTCCGGCAGA
CGCTCGACACGCTCGCGAACGGTTATGCGGCGGCCGGCCACGCGGCGACCGAAGCGCACGGCCTCGCCGTCGCGTCGATC
GCGCGGATGGTCGCGCAGCAGGCGTCGTTTCTCGCCTCGCTCGACGGCTTCTACTTCCTCGCGGGCGTCGCGCTCGTCGG
CGGCGTGTTCGCGGCATGGCAAAAAGAGATCGATTGA

Upstream 100 bases:

>100_bases
ACATCGACTACGTCGAACGACGCCTCGCCGGCGAGAACGCCGATGCGCTGATCGCGCAACGGCGCGCGGAAGCCGGCGCA
CGGCGCGGCAAGGGCCGCGC

Downstream 100 bases:

>100_bases
GTTAAAAGACAGGCTTTGGATTTCCGCGCGCCGCCTCCATGCTTTCGAAACTGACCCGCTGGCTCGACGATCGCCGCCGC
GATCGCGCGCTGCGCAGCCA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNVTSGRPPLWSRANLRADLFPWALALVTGLDYFDNAIFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQTRPPATRAFLIMILLGSALA
PIVGGLFVAYSTWRALFACTAPAGIVFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVMQQVHYQLYSGSP
MLIGLTAAGLGALAWFAYHQWNHPTPLVRLHALRERTFQIGLLLYMFYYYESTGFSYLTSRFLESGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVAHKKWFVVPGFAIAIVATLWMTRLTPQVGEAALVVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTITFATSSVIIVEQHRLAVHQTRLVERANVFDPLFRQTLDTLANGYAAAGHAATEAHGLAVASI
ARMVAQQASFLASLDGFYFLAGVALVGGVFAAWQKEID

Sequences:

>Translated_518_residues
MNVTSGRPPLWSRANLRADLFPWALALVTGLDYFDNAIFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQTRPPATRAFLIMILLGSALA
PIVGGLFVAYSTWRALFACTAPAGIVFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVMQQVHYQLYSGSP
MLIGLTAAGLGALAWFAYHQWNHPTPLVRLHALRERTFQIGLLLYMFYYYESTGFSYLTSRFLESGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVAHKKWFVVPGFAIAIVATLWMTRLTPQVGEAALVVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTITFATSSVIIVEQHRLAVHQTRLVERANVFDPLFRQTLDTLANGYAAAGHAATEAHGLAVASI
ARMVAQQASFLASLDGFYFLAGVALVGGVFAAWQKEID
>Mature_518_residues
MNVTSGRPPLWSRANLRADLFPWALALVTGLDYFDNAIFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGYFIGPMMGACRILIQISFKPQTRPPATRAFLIMILLGSALA
PIVGGLFVAYSTWRALFACTAPAGIVFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVMQQVHYQLYSGSP
MLIGLTAAGLGALAWFAYHQWNHPTPLVRLHALRERTFQIGLLLYMFYYYESTGFSYLTSRFLESGLGYPVENAGRLVGT
MSLISATALFAYLRYAKHVAHKKWFVVPGFAIAIVATLWMTRLTPQVGEAALVVPLLLRGLLLLFIVLPVANLTFRIFAI
DEYTHGYRLKNIVRQLTITFATSSVIIVEQHRLAVHQTRLVERANVFDPLFRQTLDTLANGYAAAGHAATEAHGLAVASI
ARMVAQQASFLASLDGFYFLAGVALVGGVFAAWQKEID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=455, Percent_Identity=21.5384615384615, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789042, Length=488, Percent_Identity=21.3114754098361, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790195, Length=412, Percent_Identity=22.5728155339806, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081983, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788392, Length=341, Percent_Identity=26.099706744868, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56857; Mature: 56857

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTSGRPPLWSRANLRADLFPWALALVTGLDYFDNAIFSFFASYIAGGINASPDELVWA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FIGPMMGACRILIQISFKPQTRPPATRAFLIMILLGSALAPIVGGLFVAYSTWRALFACT
EHHHHHHHHEEHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIVFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVMQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIGLTAAGLGALAWFAYHQWNHPTPLVRLHALRERTFQIGLLLYMFYYYESTGFSYLTS
EEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLESGLGYPVENAGRLVGTMSLISATALFAYLRYAKHVAHKKWFVVPGFAIAIVATLWM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRLTPQVGEAALVVPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTITF
HHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHE
ATSSVIIVEQHRLAVHQTRLVERANVFDPLFRQTLDTLANGYAAAGHAATEAHGLAVASI
ECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGVFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVTSGRPPLWSRANLRADLFPWALALVTGLDYFDNAIFSFFASYIAGGINASPDELVWA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSFGAIAAALADTSLELAFARGFQGY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FIGPMMGACRILIQISFKPQTRPPATRAFLIMILLGSALAPIVGGLFVAYSTWRALFACT
EHHHHHHHHEEHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGIVFAILALLTLPDSGRTPDDERGSGHFWPYVVFALAQGALQIVMQQVHYQLYSGSP
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLIGLTAAGLGALAWFAYHQWNHPTPLVRLHALRERTFQIGLLLYMFYYYESTGFSYLTS
EEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLESGLGYPVENAGRLVGTMSLISATALFAYLRYAKHVAHKKWFVVPGFAIAIVATLWM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRLTPQVGEAALVVPLLLRGLLLLFIVLPVANLTFRIFAIDEYTHGYRLKNIVRQLTITF
HHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHE
ATSSVIIVEQHRLAVHQTRLVERANVFDPLFRQTLDTLANGYAAAGHAATEAHGLAVASI
ECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHH
ARMVAQQASFLASLDGFYFLAGVALVGGVFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]