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The map label for this gene is tadA [H]

Identifier: 161524475

GI number: 161524475

Start: 1430978

End: 1431541

Strand: Direct

Name: tadA [H]

Synonym: Bmul_1302

Alternate gene names: 161524475

Gene position: 1430978-1431541 (Clockwise)

Preceding gene: 161524474

Following gene: 161524476

Centisome position: 41.5

GC content: 71.28

Gene sequence:

>564_bases
GTGAGCTCCGACACGCTGCACGACGCAGCGGCCGATTCCCTTCCGACGGCAGCCGCGCCGGCCTCGGCGCGCGACGTGCA
TTTCATGCGCCTCGCGCTCGCCGCAGCCGAAGAGGCGCGCGCGGCCGGCGAAGTGCCGGTCGGGGCAGTGCTCGTGCGCG
GCGACGAAGTGCTCGCGCGCGGCTTCAACCATCCGATCGGCGGCCACGATCCGTCCGCACACGCCGAAATGGCCGCGCTG
CGCATGGCCGCGCAGCATCTGCAGAACTACCGCATGCCGGGCTGCGAACTGTATGTCACGCTCGAGCCGTGCCTGATGTG
CGCGGGCGCGATCATGCATGCGCGCATCGCGCGCGTCGTATTCGGCGCCGCCGACCCGAAAACCGGCGTATGCGGCAGCG
TGATGGATGCGTTCGCGAATCCGCAGCTGAACCACCATACGGAAGTCGTCGGCGGCGTACTCGCGCACGAGTGCGGCGCC
GCGCTGAAGTCGTTCTTCGCCGAACGCCGGCGTGCGCTGCGCGACGCGCGGCTCGCGCGCGACGCGGCCGCCGGCGAATC
GTAG

Upstream 100 bases:

>100_bases
GCGGCGGCCCGATGGTGATGCCGCGCGAATACTGCCGGCGCATCGCGGAACGTCTGTGCGAGCGCGGGCTCGACGAGGTG
TCCGCCGAAGCGGGGCCGAT

Downstream 100 bases:

>100_bases
CCGGCACGGCCCGCGCGGCCGTCTCCGTGAACCGGCGCCGGTTCGGTCCCTCTAAGCAGTTCCACGATCCCGACACCTTT
CGCCATGTCCTTTCAGCCCG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSSDTLHDAAADSLPTAAAPASARDVHFMRLALAAAEEARAAGEVPVGAVLVRGDEVLARGFNHPIGGHDPSAHAEMAAL
RMAAQHLQNYRMPGCELYVTLEPCLMCAGAIMHARIARVVFGAADPKTGVCGSVMDAFANPQLNHHTEVVGGVLAHECGA
ALKSFFAERRRALRDARLARDAAAGES

Sequences:

>Translated_187_residues
MSSDTLHDAAADSLPTAAAPASARDVHFMRLALAAAEEARAAGEVPVGAVLVRGDEVLARGFNHPIGGHDPSAHAEMAAL
RMAAQHLQNYRMPGCELYVTLEPCLMCAGAIMHARIARVVFGAADPKTGVCGSVMDAFANPQLNHHTEVVGGVLAHECGA
ALKSFFAERRRALRDARLARDAAAGES
>Mature_186_residues
SSDTLHDAAADSLPTAAAPASARDVHFMRLALAAAEEARAAGEVPVGAVLVRGDEVLARGFNHPIGGHDPSAHAEMAALR
MAAQHLQNYRMPGCELYVTLEPCLMCAGAIMHARIARVVFGAADPKTGVCGSVMDAFANPQLNHHTEVVGGVLAHECGAA
LKSFFAERRRALRDARLARDAAAGES

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=162, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=49.2753623188406, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=51.5923566878981, Blast_Score=170, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17541138, Length=153, Percent_Identity=35.9477124183007, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=36, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=36.551724137931, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19559; Mature: 19428

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDTLHDAAADSLPTAAAPASARDVHFMRLALAAAEEARAAGEVPVGAVLVRGDEVLAR
CCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHH
GFNHPIGGHDPSAHAEMAALRMAAQHLQNYRMPGCELYVTLEPCLMCAGAIMHARIARVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
FGAADPKTGVCGSVMDAFANPQLNHHTEVVGGVLAHECGAALKSFFAERRRALRDARLAR
HCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAAGES
HHCCCCC
>Mature Secondary Structure 
SSDTLHDAAADSLPTAAAPASARDVHFMRLALAAAEEARAAGEVPVGAVLVRGDEVLAR
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHH
GFNHPIGGHDPSAHAEMAALRMAAQHLQNYRMPGCELYVTLEPCLMCAGAIMHARIARVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
FGAADPKTGVCGSVMDAFANPQLNHHTEVVGGVLAHECGAALKSFFAERRRALRDARLAR
HCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAAGES
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]