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The map label for this gene is dapL [H]

Identifier: 161524421

GI number: 161524421

Start: 1370715

End: 1371947

Strand: Reverse

Name: dapL [H]

Synonym: Bmul_1248

Alternate gene names: 161524421

Gene position: 1371947-1370715 (Counterclockwise)

Preceding gene: 161524427

Following gene: 161524420

Centisome position: 39.78

GC content: 69.51

Gene sequence:

>1233_bases
ATGGCCGCTTCGCCCGTGAACCCTCGACTCGACTCGCTCCAGCCCTATCCCTTCGAAAAGCTGCGCGCCCTGTTCAAGGA
CGTGACGCCCCCTGCCGGCCTCAAACCGATCAGCTTCGGCATCGGCGAGCCCAAGCACCCGACGCCCGCGCTGATCCGCG
ACGCGGCCGTGGCCGCGCTCGACGGCCTCGCCGCCTATCCGGCGACGGCCGGCTCGGACGCGCTGCGCACGTCGATCGCG
CGCTGGCTCGAGCGCCGCTACGGGCTGCCGGCCGTCGACGCGGCGACGCAGGTGCTGCCGGTCTCGGGCTCGCGCGAGGC
GCTGTTCTCGCTCGCGCAGACAGTGATCGACAGCCGCCCGGCCGAAAGCGGGCAGAAAGCGATCGTACTCTGTCCGAATC
CGTTCTATCAAATTTACGAAGGTGCGGCGCTGCTGGCCGGCGCCGAGCCCTATTTCGCGAACAGCGATCCGGCACGCAAC
TTCGCCTGCGACTACGCGGCCGTGCCGGACGACGTCTGGGCGCGCACGCAGCTGCTCTACGTCTGCTCGCCGGGCAACCC
GACCGGCGCCGTGCTGACGCTCGACGACTGGCGCGAGCTGTTCGCGCTGTCCGATCGCCACGGCTTCGTGATCGCGTCCG
ACGAGTGCTATTCGGAAATCTATTTCGACGAAGCGACGCCGCCGCTCGGCGGCCTCGAGGCCGCGCACCGCCTCGGCCGC
GGCTTCGAGCGGCTCGTGATGCTGTCGAGCCTGTCGAAGCGCTCGAACGTGCCCGGCATGCGCTCGGGCTTCGTCGCGGG
CGACGCGGCGCTGCTGAAGAAATTCCTGCTGTACCGCACGTACCACGGCGCCGCGCTGTCGCCCGTGTGGCAGCACGCGA
GCATCGCCGCGTGGAACGACGAGGCGCACGTGCGCGAGAACCGCGCGCTGTACCTGCAGAAGTTCAGCACCGTGACGCCG
ATGCTCGCCGACGTGCTCGACGTGAAGCTGCCGGACGCCGCGTTCTATCTGTGGGCGAACGTCGCGCGCACCGGCCTGTC
GGACACCGAGTTCGCCCGCCGCCTGTACGCCGACTATAATGTGACGGTTCTGCCCGGCTCGTACCTCGCGCGCAACGCGC
ACGGCACGAACCCGGGCCGCGATTTCATCCGGATCGCGCTCGTCGCGGGCACCCCCGAATGCGTCGAGGGCGCGCAACGC
ATCGTCGATTTCTGCCGCGGCATCGCGCAGTAA

Upstream 100 bases:

>100_bases
GACCGGATTTCGTCACGCTATAATCGTCCGTTGCGACGCGCGCCGCCGGCGCCCGTTCGCCGTCGCGGCGCCGCCGCTCC
TTTCGCTCCAACCGGCCGCG

Downstream 100 bases:

>100_bases
GACGTCCATCCCGATCAATTCCATCCATCTCCTGCGAAAACGAACATGTCGCAACAACTTCAGCAAATCATCGATAACGC
CTGGGAAAACCGTGCGGAGC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPPAGLKPISFGIGEPKHPTPALIRDAAVAALDGLAAYPATAGSDALRTSIA
RWLERRYGLPAVDAATQVLPVSGSREALFSLAQTVIDSRPAESGQKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEATPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFSTVTP
MLADVLDVKLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARNAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRGIAQ

Sequences:

>Translated_410_residues
MAASPVNPRLDSLQPYPFEKLRALFKDVTPPAGLKPISFGIGEPKHPTPALIRDAAVAALDGLAAYPATAGSDALRTSIA
RWLERRYGLPAVDAATQVLPVSGSREALFSLAQTVIDSRPAESGQKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARN
FACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEATPPLGGLEAAHRLGR
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFSTVTP
MLADVLDVKLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARNAHGTNPGRDFIRIALVAGTPECVEGAQR
IVDFCRGIAQ
>Mature_409_residues
AASPVNPRLDSLQPYPFEKLRALFKDVTPPAGLKPISFGIGEPKHPTPALIRDAAVAALDGLAAYPATAGSDALRTSIAR
WLERRYGLPAVDAATQVLPVSGSREALFSLAQTVIDSRPAESGQKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNF
ACDYAAVPDDVWARTQLLYVCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEATPPLGGLEAAHRLGRG
FERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWNDEAHVRENRALYLQKFSTVTPM
LADVLDVKLPDAAFYLWANVARTGLSDTEFARRLYADYNVTVLPGSYLARNAHGTNPGRDFIRIALVAGTPECVEGAQRI
VDFCRGIAQ

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=275, Percent_Identity=25.0909090909091, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI169881279, Length=275, Percent_Identity=25.0909090909091, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=407, Percent_Identity=26.2899262899263, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=24.5333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787909, Length=372, Percent_Identity=22.5806451612903, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=402, Percent_Identity=23.3830845771144, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859735, Length=360, Percent_Identity=24.4444444444444, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44522; Mature: 44391

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPVNPRLDSLQPYPFEKLRALFKDVTPPAGLKPISFGIGEPKHPTPALIRDAAVAAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHH
DGLAAYPATAGSDALRTSIARWLERRYGLPAVDAATQVLPVSGSREALFSLAQTVIDSRP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCEEEECCCCHHHHHHHHHHHHHCCC
AESGQKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDDVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEATPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHEECCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFSTVTPMLADVLDVKLPDAAFYLWANVARTGLSDTEFARRLYADYN
CHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
VTVLPGSYLARNAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRGIAQ
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASPVNPRLDSLQPYPFEKLRALFKDVTPPAGLKPISFGIGEPKHPTPALIRDAAVAAL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHH
DGLAAYPATAGSDALRTSIARWLERRYGLPAVDAATQVLPVSGSREALFSLAQTVIDSRP
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCEEEECCCCHHHHHHHHHHHHHCCC
AESGQKAIVLCPNPFYQIYEGAALLAGAEPYFANSDPARNFACDYAAVPDDVWARTQLLY
CCCCCEEEEECCCHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEE
VCSPGNPTGAVLTLDDWRELFALSDRHGFVIASDECYSEIYFDEATPPLGGLEAAHRLGR
EECCCCCCEEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHEECCCCCCCCHHHHHHHHHH
GFERLVMLSSLSKRSNVPGMRSGFVAGDAALLKKFLLYRTYHGAALSPVWQHASIAAWND
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCEEEEECC
EAHVRENRALYLQKFSTVTPMLADVLDVKLPDAAFYLWANVARTGLSDTEFARRLYADYN
CHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCC
VTVLPGSYLARNAHGTNPGRDFIRIALVAGTPECVEGAQRIVDFCRGIAQ
EEEECCHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA