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The map label for this gene is btuE [C]

Identifier: 161524415

GI number: 161524415

Start: 1365272

End: 1365751

Strand: Direct

Name: btuE [C]

Synonym: Bmul_1242

Alternate gene names: 161524415

Gene position: 1365272-1365751 (Clockwise)

Preceding gene: 161524413

Following gene: 161524422

Centisome position: 39.59

GC content: 61.25

Gene sequence:

>480_bases
ATGTCTTCCCTGTATACATTCAGCGCCGACACGCTGGCCGGTGTGCCGAGCACGCTCGATGTCTATCGCGGCAAGGTGCT
CCTGATCGTCAATACCGCGAGCGAGTGCGGTTTCACGCCGCAGTACGCGGGGCTGCAGAAGCTGTACGAACGCTACGCGG
CGCGCGGCTTTTTCGTGCTCGGCTTTCCATGCAACCAGTTCGGCAAGCAGGAGCCGGGCGACGCCGAGCAGATCGGCGCC
TTCTGCGAGCGCAATTACGGCGTCACGTTTCCGATATTCGCGAAGATCGACGTGAAGGGTCCGAACGCGCATCCGCTGTA
TCGCTACCTGACCGACGAGTCGCCCGGCATCTTCGGCCTGAAGGCGATCAAGTGGAACTTCACGAAATTCCTGATCGACC
GCGACGGGCGCATCGTGAAGCGCTACGCGCCGTCGACAAAGCCCGAGGACATCGCCGCGGATATCGAAAAGCTGCTTTGA

Upstream 100 bases:

>100_bases
TGCGCACCGTTCGCGCACGCATCGGCCGTCCGGCCAATGTCGCGACGGCCCGATTTGCCGTAGCATTCACGTCGATCCGG
TTTCGTCAAAGGAGTGCCCG

Downstream 100 bases:

>100_bases
CGCGCGGTGCGCGCCCGCATCGGGCACGCGGGCCGCGGCGGCTACAGGATCGGCGCGAACAGCCGCGCGACGTGCATCGC
GATGCGCCGCCATGCGGGCG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSSLYTFSADTLAGVPSTLDVYRGKVLLIVNTASECGFTPQYAGLQKLYERYAARGFFVLGFPCNQFGKQEPGDAEQIGA
FCERNYGVTFPIFAKIDVKGPNAHPLYRYLTDESPGIFGLKAIKWNFTKFLIDRDGRIVKRYAPSTKPEDIAADIEKLL

Sequences:

>Translated_159_residues
MSSLYTFSADTLAGVPSTLDVYRGKVLLIVNTASECGFTPQYAGLQKLYERYAARGFFVLGFPCNQFGKQEPGDAEQIGA
FCERNYGVTFPIFAKIDVKGPNAHPLYRYLTDESPGIFGLKAIKWNFTKFLIDRDGRIVKRYAPSTKPEDIAADIEKLL
>Mature_158_residues
SSLYTFSADTLAGVPSTLDVYRGKVLLIVNTASECGFTPQYAGLQKLYERYAARGFFVLGFPCNQFGKQEPGDAEQIGAF
CERNYGVTFPIFAKIDVKGPNAHPLYRYLTDESPGIFGLKAIKWNFTKFLIDRDGRIVKRYAPSTKPEDIAADIEKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=48.0769230769231, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=48.0769230769231, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=43.312101910828, Blast_Score=132, Evalue=1e-31,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=40.625, Blast_Score=131, Evalue=2e-31,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=113, Evalue=9e-26,
Organism=Homo sapiens, GI41406084, Length=186, Percent_Identity=38.7096774193548, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI4557629, Length=158, Percent_Identity=36.7088607594937, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI6006001, Length=180, Percent_Identity=33.8888888888889, Blast_Score=90, Evalue=8e-19,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=34.8066298342541, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=31.638418079096, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=54.2857142857143, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=42.5149700598802, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=46.25, Blast_Score=145, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=45.625, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=39.2405063291139, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=40.7407407407407, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=34.8066298342541, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=35.3591160220994, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71999642, Length=77, Percent_Identity=38.961038961039, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=36.8421052631579, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=53.1645569620253, Blast_Score=190, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=52.8301886792453, Blast_Score=188, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=45.9119496855346, Blast_Score=159, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=47.5, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=47.5, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=47.5, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=44.0251572327044, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17750; Mature: 17618

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLYTFSADTLAGVPSTLDVYRGKVLLIVNTASECGFTPQYAGLQKLYERYAARGFFVL
CCCEEEECCHHHHCCCCHHHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAEQIGAFCERNYGVTFPIFAKIDVKGPNAHPLYRYLTDESPGIFGL
ECCHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCEEEE
KAIKWNFTKFLIDRDGRIVKRYAPSTKPEDIAADIEKLL
EEEEECCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHC
>Mature Secondary Structure 
SSLYTFSADTLAGVPSTLDVYRGKVLLIVNTASECGFTPQYAGLQKLYERYAARGFFVL
CCEEEECCHHHHCCCCHHHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCEEEE
GFPCNQFGKQEPGDAEQIGAFCERNYGVTFPIFAKIDVKGPNAHPLYRYLTDESPGIFGL
ECCHHHHCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCEEEECCCCCCEEEE
KAIKWNFTKFLIDRDGRIVKRYAPSTKPEDIAADIEKLL
EEEEECCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]