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The map label for this gene is argA [H]

Identifier: 161524290

GI number: 161524290

Start: 1220572

End: 1221951

Strand: Reverse

Name: argA [H]

Synonym: Bmul_1115

Alternate gene names: 161524290

Gene position: 1221951-1220572 (Counterclockwise)

Preceding gene: 161524296

Following gene: 161524289

Centisome position: 35.43

GC content: 67.03

Gene sequence:

>1380_bases
ATGAATTCCCAAACCGACCTCCCCCCGGCGCAGACCGCCGACGCGAACCTGCCGGCCACCGACGATTCGGCCCTCAGGCA
CGCGCAGTTCGTCGACTGGATGCGTTCCGTCGCGCCCTATATCCACAAGTTCCGCAACAACACGTTCGTCGTGGGGTTCG
GCGGCGAGGTGGTGCAGCAGGGGCTGCTGAACGCGCTCGTGTCCGACATCGCGCTGCTGCAGGCGATGGGCATCCAGATC
GTGCTCGTGCACGGCTCGCGGCCGCAGGTCGAGGAGCAGCTGAACCTGCACGGCGTCGAATCGGAGTTTTCGCACGGGCT
GCGGATCACCGATGCGCGCGCACTCGAATCCGCGAAGGAAGCGGCCGGCGAAGTGCGCCTCGACATCGAGGCCGCGATCA
GCCAAGGTCTGCCGAACTCGCCGATGGCGCATGCGCACATCAGCGTCGTGTCGGGCAACTTCGTCACCGCGCGGCCGGTC
GGCATTCTCGACGGCGTCGATTTCGCGCACACGGGTATCGTGCGCAAGATCGACGCGGAGTCGATCCGCCATTCGCTCGC
GAGCCGCAAGCTCGTGCTGCTGTCGCCGCTCGGCTTCTCGCCGACGGGCGAGGCGTTCAACCTGTCGATGGAAGACGTCG
CGTCGGCCGCCGCGATCGCGCTGCGCGCGGACAAGATCATCTTTCTGACGGACGGCCCCGGCATCGTCGACGACGCGGGC
GAGCTGATCCGCGAAATGTCGCTCGACGCGGCGGCCGAACTGCTCGACTCGGGCAACATCCAGGGCGACGACGCGTTCTT
CCTCAAGCATTCGATCCGCGCGTGCCGCGGCGGCGTCACGCGTGCGCACCTGATCCCGCAGTCGCTCGACGGCAGCATGC
TGCTCGAGCTGTTCCTGCACGACGGCGTCGGCACGATGATCTCGTACGAGAACCTCGAGAGCCTGCGCGAGGCGACGCCG
GACGACGTCGGCGGCATCCTGTCGCTGATCGAGCCGCTCGAGGCGGACGGCACGCTGGTGCGCCGCGGCCGCCACCAGAT
CGAACGCGACATCGATCATTTCTCGGTGATCGAGCACGACGGCGTGCTGTTCGGTTGCGCGGCGCTGTATCCGTACCAGC
AGGAGAAGATCGGCGAGATGGCGTGCCTGACGGTCGCGCCGGAAGCGCAAGGCTCGGGCGACGGCGAACGGCTGCTCAAG
CGCATCGAGCAGCGTGCGCGTGCGCGCGGCCTCACACACATCTTCGTGCTCACGACGCGCACCGAGCACTGGTTCCTGAA
GCGCGGCTTCGTCAAGGCGACGGTCGACGACCTGCCGGAAGACCGCCGCAAACTCTATAACTGGCAGCGCAAGTCGCTCG
TGCTGATGAAGCAGCTCTGA

Upstream 100 bases:

>100_bases
TCGGCCGCACCATCCGGGTGCCGGGCCGACGGCGCTTTTGCCCGCGTCGCCGCGGGACTTTTAGGTACATTCGACATGGG
GGCGCATTATAATCCCGCCC

Downstream 100 bases:

>100_bases
GCGCAGGCACGCCTGCCCTCCCCCAGACCGATTACAGGAGAAGTACACGATGGCTCGAATGATTCAATGCGCGAAGCTCG
GCAAGGAAGCCGAAGGCCTC

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNSQTDLPPAQTADANLPATDDSALRHAQFVDWMRSVAPYIHKFRNNTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLNLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTDGPGIVDDAG
ELIREMSLDAAAELLDSGNIQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLEADGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKATVDDLPEDRRKLYNWQRKSLVLMKQL

Sequences:

>Translated_459_residues
MNSQTDLPPAQTADANLPATDDSALRHAQFVDWMRSVAPYIHKFRNNTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLNLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTDGPGIVDDAG
ELIREMSLDAAAELLDSGNIQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLEADGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKATVDDLPEDRRKLYNWQRKSLVLMKQL
>Mature_459_residues
MNSQTDLPPAQTADANLPATDDSALRHAQFVDWMRSVAPYIHKFRNNTFVVGFGGEVVQQGLLNALVSDIALLQAMGIQI
VLVHGSRPQVEEQLNLHGVESEFSHGLRITDARALESAKEAAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPV
GILDGVDFAHTGIVRKIDAESIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTDGPGIVDDAG
ELIREMSLDAAAELLDSGNIQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLHDGVGTMISYENLESLREATP
DDVGGILSLIEPLEADGTLVRRGRHQIERDIDHFSVIEHDGVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLK
RIEQRARARGLTHIFVLTTRTEHWFLKRGFVKATVDDLPEDRRKLYNWQRKSLVLMKQL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=438, Percent_Identity=45.4337899543379, Blast_Score=414, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6320913, Length=301, Percent_Identity=25.2491694352159, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 50121; Mature: 50121

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQTDLPPAQTADANLPATDDSALRHAQFVDWMRSVAPYIHKFRNNTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLNLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCCCCCCCHHHCCHHHCCCHH
SIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTDGPGIVDDAG
HHHHHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCHHHHH
ELIREMSLDAAAELLDSGNIQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLEADGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKATVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSQTDLPPAQTADANLPATDDSALRHAQFVDWMRSVAPYIHKFRNNTFVVGFGGEVVQQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHH
GLLNALVSDIALLQAMGIQIVLVHGSRPQVEEQLNLHGVESEFSHGLRITDARALESAKE
HHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCCHHHHCCCEEEHHHHHHHHHH
AAGEVRLDIEAAISQGLPNSPMAHAHISVVSGNFVTARPVGILDGVDFAHTGIVRKIDAE
HCCCEEEEHHHHHHCCCCCCCCCEEEEEEEECCEEEECCCCCCCCCCHHHCCHHHCCCHH
SIRHSLASRKLVLLSPLGFSPTGEAFNLSMEDVASAAAIALRADKIIFLTDGPGIVDDAG
HHHHHHHHCCEEEEECCCCCCCCCEEECCHHHHHHHHHHEEECCEEEEEECCCCCHHHHH
ELIREMSLDAAAELLDSGNIQGDDAFFLKHSIRACRGGVTRAHLIPQSLDGSMLLELFLH
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEHCCCCCCCHHHHHHHHHH
DGVGTMISYENLESLREATPDDVGGILSLIEPLEADGTLVRRGRHQIERDIDHFSVIEHD
CCCCHHEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHEECC
GVLFGCAALYPYQQEKIGEMACLTVAPEAQGSGDGERLLKRIEQRARARGLTHIFVLTTR
CEEEEHHHHCCCCHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEC
TEHWFLKRGFVKATVDDLPEDRRKLYNWQRKSLVLMKQL
CHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]