Click here to switch to the map view.

The map label for this gene is alsR [H]

Identifier: 161524285

GI number: 161524285

Start: 1214474

End: 1215376

Strand: Reverse

Name: alsR [H]

Synonym: Bmul_1110

Alternate gene names: 161524285

Gene position: 1215376-1214474 (Counterclockwise)

Preceding gene: 161524289

Following gene: 161524284

Centisome position: 35.24

GC content: 67.0

Gene sequence:

>903_bases
ATGGAACTGAGGCAGTTGCGCTACTTCGTGGCCGTCGCCGAAGAACTGCATTTCGGGCGCGCGGCGAAGCGCCTGTTCAT
CTCGCAGCCGGCGCTGAGTTTCGACATCCGCAAGTTCGAGGAGACGCTCGGCGTGCAGCTGCTGTCGCGCACGAACAAGG
CCGTCGCGTTGACCAACGCGGGCGAAGTGCTGCTCGGCGAAGCGCGCCGGCTGCTGCTGCAGGCCGCCGAAGCGGAACGG
CTGACCGTGCGATCCGCATCCGGTCTCGCGGGCCGGCTGCGGATCGGCTTCGTCCATTCGATGCTCTATCGAGGGCTGCC
CGATGCGGTACGTCGTTTCGAGGCCGATTACCCCGGCGTCGAGATCGTCCTGAGCGAGATGAACACGCAGGCGCAAGTAC
AGGCCGTGCAGCGCGGCCAGATCGACCTCGGCTATGCGCACTGGGGCCGCTTTCCGCCCGAGGTCGAATCGGCGCCCATC
TATGCGGAGCCGTTCGTCTGCTGCCTGCCGGCCGCGCATCCGTTCGCGCGACGCAGAAAGATCGCACTCGCGGCACTCGC
CGCGGAACCGTTCATCCTGTTTCCGCGCGACGCCGCACCGCACTATCACGATCTGATCATCGCGCAGTGCGTGAACGCCG
GGTTCAGCCCGGTGATTCGCCACGAGGCGCGGCTGTGGCAGACGATCCTGTCGATGATCGAGTTCGGCATGGGCATTGCA
CTCGTGCCGCGCGTGCTGCAGCAGGCCAAAAGCGAGCGGCTCGCGTTCCGGCCGCTGAAGGACGCGTCGCTCGAATCGCG
CACGCTCGAGCTGAAGCGCAGCGGCAGCGCGGAGCCGGTCGCGCTGCGCTTCGCCGAATATGTGCGTGCGTCGATCGATG
CGCTGCCGGCACGCGCGAGTTAG

Upstream 100 bases:

>100_bases
GTTTCGGACAGCGTAGGCCTGCGGTCGATAAGCGTCCAATACAGGATTTATTCGGTACGATAGATATCGCTTATCGACGC
GCGGACGAGGAGAACAGACG

Downstream 100 bases:

>100_bases
CGCGCCGATTGCGGCATGGCGACCTCGCGTTCGGCGTGCGCGCCGTTCGAAAACGAGCGTCGCGGCCGGACCTCGGCCCG
CCCTGCGCATGCGCTCAAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEETLGVQLLSRTNKAVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEIVLSEMNTQAQVQAVQRGQIDLGYAHWGRFPPEVESAPI
YAEPFVCCLPAAHPFARRRKIALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPVIRHEARLWQTILSMIEFGMGIA
LVPRVLQQAKSERLAFRPLKDASLESRTLELKRSGSAEPVALRFAEYVRASIDALPARAS

Sequences:

>Translated_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEETLGVQLLSRTNKAVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEIVLSEMNTQAQVQAVQRGQIDLGYAHWGRFPPEVESAPI
YAEPFVCCLPAAHPFARRRKIALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPVIRHEARLWQTILSMIEFGMGIA
LVPRVLQQAKSERLAFRPLKDASLESRTLELKRSGSAEPVALRFAEYVRASIDALPARAS
>Mature_300_residues
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEETLGVQLLSRTNKAVALTNAGEVLLGEARRLLLQAAEAER
LTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGVEIVLSEMNTQAQVQAVQRGQIDLGYAHWGRFPPEVESAPI
YAEPFVCCLPAAHPFARRRKIALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPVIRHEARLWQTILSMIEFGMGIA
LVPRVLQQAKSERLAFRPLKDASLESRTLELKRSGSAEPVALRFAEYVRASIDALPARAS

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=262, Percent_Identity=38.1679389312977, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI2367136, Length=262, Percent_Identity=36.6412213740458, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788887, Length=264, Percent_Identity=35.6060606060606, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790399, Length=300, Percent_Identity=29.6666666666667, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI157672245, Length=235, Percent_Identity=32.7659574468085, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=30.0411522633745, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788748, Length=241, Percent_Identity=28.6307053941909, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790208, Length=284, Percent_Identity=29.2253521126761, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787530, Length=294, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=268, Percent_Identity=27.2388059701493, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=199, Percent_Identity=32.1608040201005, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788296, Length=308, Percent_Identity=25.974025974026, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=185, Percent_Identity=30.8108108108108, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=214, Percent_Identity=28.0373831775701, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788297, Length=153, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=249, Percent_Identity=24.4979919678715, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787589, Length=128, Percent_Identity=39.0625, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994962, Length=81, Percent_Identity=44.4444444444444, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790262, Length=304, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33382; Mature: 33382

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEETLGVQLLSRTNKAVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GEVLLGEARRLLLQAAEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGV
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EIVLSEMNTQAQVQAVQRGQIDLGYAHWGRFPPEVESAPIYAEPFVCCLPAAHPFARRRK
EEEEECCCCHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
IALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPVIRHEARLWQTILSMIEFGMGIA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQAKSERLAFRPLKDASLESRTLELKRSGSAEPVALRFAEYVRASIDALPARAS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MELRQLRYFVAVAEELHFGRAAKRLFISQPALSFDIRKFEETLGVQLLSRTNKAVALTNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GEVLLGEARRLLLQAAEAERLTVRSASGLAGRLRIGFVHSMLYRGLPDAVRRFEADYPGV
CHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EIVLSEMNTQAQVQAVQRGQIDLGYAHWGRFPPEVESAPIYAEPFVCCLPAAHPFARRRK
EEEEECCCCHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCCCCHHEECCCCCHHHHHHH
IALAALAAEPFILFPRDAAPHYHDLIIAQCVNAGFSPVIRHEARLWQTILSMIEFGMGIA
HHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LVPRVLQQAKSERLAFRPLKDASLESRTLELKRSGSAEPVALRFAEYVRASIDALPARAS
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]