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The map label for this gene is upp [H]

Identifier: 161524161

GI number: 161524161

Start: 1079228

End: 1079878

Strand: Reverse

Name: upp [H]

Synonym: Bmul_0985

Alternate gene names: 161524161

Gene position: 1079878-1079228 (Counterclockwise)

Preceding gene: 161524178

Following gene: 161524160

Centisome position: 31.31

GC content: 65.28

Gene sequence:

>651_bases
ATGAAACAGGACAGCCGTTTCCCGAATCTCTTCATCCTCGATCACCCGCTGATCCAGCACAAGCTCACGCACATGCGCGA
CAAGGACACGTCGACGCGCACGTTCCGCGAACTGCTGCGCGAGATCACGCTGCTGATGGGCTACGAGATCACCCGCAATC
TGCCGATCACGACGAAGCGGGTCGAAACCCCGCTCGTCGAGATCGATGCGCCGGTGATCGCGGGCAAGAAGCTCGCGATC
GTGCCCGTGCTGCGCGCGGGCGTCGGGATGTCGGACGGCCTGCTCGACCTGATCCCATCCGCGCGCGTCGGCCATATCGG
CGTCTATCGTGCGGACGATCATCGGCCGGTCGAATATCTCGTGCGGCTGCCCGATCTCGAGGACCGCATCTTCATCCTGT
GCGACCCGATGGTCGCGACCGGCTATTCGGCCGTGCACGCCGTCGACGTGCTGAAGCGCCGCAACGTGCCGGCCGCGAAC
ATCATGTTCGTCGCGCTCGTCGCCGCGCCCGAGGGCGTACAGGTGTTCCAGGACGCGCACCCCGACGTGAAGCTGTTCGT
CGCGTCGCTCGACTCGCACCTGAACGAACACGCCTACATCGTGCCGGGTCTCGGCGACGCGGGCGACCGCCTGTTCGGCA
CCAAGAACTGA

Upstream 100 bases:

>100_bases
GCGCGGCGCGCCTTGGTAAAATTGCGACCATGCGCGCGCGACCGGCTTGCGCCTGCCGCCGCCCTCCCGATCCCCTTTTG
CCGCAAGGCGCTCCCCCGTC

Downstream 100 bases:

>100_bases
CGCAGCGGCGGCCGGCCGCCCGCGCGCATGCCGCGCGGCGCGGCCGTCCCGGCCGTTCGGCCAGGCGCGGCGCGCCGTTC
GGGCGGTCGCCGCGTGATAA

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
>Mature_216_residues
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKRVETPLVEIDAPVIAGKKLAI
VPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAAN
IMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=33.1683168316832, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=33.1683168316832, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI87082118, Length=208, Percent_Identity=47.5961538461538, Blast_Score=194, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=26.7942583732057, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=26.7942583732057, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6321920, Length=211, Percent_Identity=35.5450236966825, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI45550449, Length=222, Percent_Identity=34.2342342342342, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573516, Length=222, Percent_Identity=34.2342342342342, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28573514, Length=222, Percent_Identity=34.2342342342342, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28573512, Length=222, Percent_Identity=34.2342342342342, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21358379, Length=171, Percent_Identity=30.4093567251462, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 24029; Mature: 24029

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYL
HCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCHHHEEEEEEEECCCCHHHHHCCC
PDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
CCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQDSRFPNLFILDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTKR
CCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCHHH
VETPLVEIDAPVIAGKKLAIVPVLRAGVGMSDGLLDLIPSARVGHIGVYRADDHRPVEYL
HCCCEEEECCCEECCCCEEEEEHHHHCCCCCCCHHHHCCCCCCCEEEEEECCCCCCHHHE
VRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAH
EECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCHHHEEEEEEEECCCCHHHHHCCC
PDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
CCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA