Click here to switch to the map view.

The map label for this gene is panC [H]

Identifier: 161524031

GI number: 161524031

Start: 927210

End: 928049

Strand: Reverse

Name: panC [H]

Synonym: Bmul_0852

Alternate gene names: 161524031

Gene position: 928049-927210 (Counterclockwise)

Preceding gene: 161524032

Following gene: 161524030

Centisome position: 26.91

GC content: 67.62

Gene sequence:

>840_bases
ATGAAAGTCATCAGCTCGATCCAGGAACTGCGCGACCAGCTGCGCGGCCAGAACCGCACGGCGTTCGTGCCGACGATGGG
CAATCTGCACGAAGGCCATCTGTCGCTGATGCGCCTCGCGCGCCAGCACGGCGATCCGGTCGTGGCGAGCATTTTCGTCA
ACCGCCTGCAGTTCGGTCCGAACGAGGATTTCGACAAGTATCCGCGCACGCTCCAGGACGACATCGAGAAGCTGCAGAAG
GAAAACGTCTACGTGCTGTTCGCGCCGACCGAGCGCGACATGTATCCGGAGCCGCAGGAATACCGCGTGCAGCCGCCGGA
CGATCTCGGCGGCATTCTCGAAGGCGAGTTCCGGCCGGGCTTCTTCACGGGCGTCTGCACGGTCGTCGCCAAGCTGATGG
CCTGCGTGCAGCCGCGCGTGGCCGTGTTCGGCAAGAAGGACTATCAGCAGCTGATGATCGTGCGGCGCATGTGCCAGCAG
CTCGCGCTGCCGGTCGACATCGTCGCGGCCGAGACCGTCCGCGACACGGACGGACTCGCGCTGTCGTCGCGCAACCGCTA
TCTGTCGGACGCCGAGCGCAGCGAAGCGCCGGAACTCGCGCGCACGCTGCAGCGCGTGCGCGAGCGCGTGCTGGCCGGCG
AACGCGACCTCGGCAAGCTCGAGCAGGACGCGCGCACGCATCTCGCGGGCCGCGGCTGGGCGCCCGACTACATCTCGATC
CGCCGCCGCGCGAACCTGATCGCACCGAACGCCGCCGAACTCGACGCCGGCGAGCCGCTCGTCGTGCTCGCAGCCGCGAA
GCTCGGCGCGACGCGCCTCATCGACAACCTGGAAATCTGA

Upstream 100 bases:

>100_bases
GCCCGCCGCGTGGTCTGCGCGCGGGCGCGTTTCACTCCGACCCCGACGCCGCCTGCCGCGGCGGCAACGCGCGCACGCGC
GAGGAATTCGCTACCCGATC

Downstream 100 bases:

>100_bases
CGGCCGCCGAGCGCCCCGTCACGACGCATCACGGAGACATCATGCAGCGCCACATGCTCAAATCGAAAATCCATCGCGCG
GCCGTCACGCACTGCGAGCT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPDDLGGILEGEFRPGFFTGVCTVVAKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIVAAETVRDTDGLALSSRNRYLSDAERSEAPELARTLQRVRERVLAGERDLGKLEQDARTHLAGRGWAPDYISI
RRRANLIAPNAAELDAGEPLVVLAAAKLGATRLIDNLEI

Sequences:

>Translated_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPDDLGGILEGEFRPGFFTGVCTVVAKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIVAAETVRDTDGLALSSRNRYLSDAERSEAPELARTLQRVRERVLAGERDLGKLEQDARTHLAGRGWAPDYISI
RRRANLIAPNAAELDAGEPLVVLAAAKLGATRLIDNLEI
>Mature_279_residues
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQK
ENVYVLFAPTERDMYPEPQEYRVQPPDDLGGILEGEFRPGFFTGVCTVVAKLMACVQPRVAVFGKKDYQQLMIVRRMCQQ
LALPVDIVAAETVRDTDGLALSSRNRYLSDAERSEAPELARTLQRVRERVLAGERDLGKLEQDARTHLAGRGWAPDYISI
RRRANLIAPNAAELDAGEPLVVLAAAKLGATRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=43.6170212765958, Blast_Score=214, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=299, Percent_Identity=37.4581939799331, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31376; Mature: 31376

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
FFTGVCTVVAKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIVAAETVRDTDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSDAERSEAPELARTLQRVRERVLAGERDLGKLEQDARTHLAGRGWAPDYISI
ECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RRRANLIAPNAAELDAGEPLVVLAAAKLGATRLIDNLEI
HHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGP
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPDDLGGILEGEFRPG
CCCHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
FFTGVCTVVAKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVDIVAAETVRDTDGLA
HHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
LSSRNRYLSDAERSEAPELARTLQRVRERVLAGERDLGKLEQDARTHLAGRGWAPDYISI
ECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RRRANLIAPNAAELDAGEPLVVLAAAKLGATRLIDNLEI
HHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA