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The map label for this gene is bah [H]

Identifier: 161523732

GI number: 161523732

Start: 601764

End: 602732

Strand: Direct

Name: bah [H]

Synonym: Bmul_0552

Alternate gene names: 161523732

Gene position: 601764-602732 (Clockwise)

Preceding gene: 161523731

Following gene: 161523734

Centisome position: 17.45

GC content: 71.83

Gene sequence:

>969_bases
ATGAGTTGGCAAAGCAGAGTCGCCTGCTGGTTGTTGCGCTGGCAGTTCCGTCCCGAGACGCTGCGCCCGGTGCTCGACCC
GGCCCGCGCGCGGCGCTTCACCGATCTGCGGATGCGGACGATCGTGCCGCGCCGGGCGCCGTCCGGCTATCGGCTGCGCC
AATGCTACGGCGCCGGCGATGCACCGCTGCGCGGCGAATGGCTCGAGCGCACCGACGTGCCGGCCGGTGGCGCGACGGGG
CCGACGCTGCTGTACTTCCACGGCGGCGGTTACTACTTCTGTTCGACGAAGACGCATCGCGCGCTCGTGTTCGGGCTGAC
GAAGCGGGCGCGCGTGCGTTCGTTCTCGCTCGACTATCGGCTCGCGCCCGAGAACCGCTTTCCGGCCGCACTCGACGATG
CGCTCGCCGCATACCGTCGGCTGATTGCGCTCGGCACGCGGCCCGAGTCGATCGTGCTCGGCGGCGACTCGGCCGGCGGC
GGCCTTGCGCTCGCGACGCTCGTCGCGCTGCGCGACGCAGGCGAACCGCTGCCGGCCGGCGCGATCCTGTTTTCGCCGTG
GACCGACCTTGCGGGCAGCGGCGACACGCTGCGCACGCACGACGGCATCGATCCGATGTTCGCCGGCGCGGCGCTGCCGA
AGGCCGCGAAGCTCTATCTCGGCGATACGCCCGCGACGCATCCGTACGCCTCGCCGCTCTACGCGGATTTCTCGGGCTTG
CCGCCGCTCTACATCCAGGTCGGCAGTACCGAGGTGCTGCTCGACGACTCGCGCCGCGTCGCCGACAAGGCGAGGGCCGC
CGGCGTGCCGGTCGAGATCGAGATCTGGCCCGGCATGCCGCACGTGTGGCAGTTGTACACGCCGATGCTGCCGGAGTCGC
GCGACGCGCTCGATCGCGCGGCCGCGTTCCTGCGCCGCGTGGCGGTCGAGCGCGCGGTTCAGCGCGTCGGCGAGCCGTCG
ATCGCCTGA

Upstream 100 bases:

>100_bases
CCGCGAACTGAGCGCCGCCGTTTGATATAGAGCCTCCTGTCCAGCGACGCGCGCACGATCGCACGTACCATCGTCACACT
ACGATTGCGGAGTGTGTCCG

Downstream 100 bases:

>100_bases
TAGGCGGTCTGCACGGCCTCGGTCCCGTACTTGCGTTCGAGCCGGCGCACGGTGAAGTGGCCGTGCGCCATCTGCTGGAA
GTGATCGATGAACAGCGTGT

Product: alpha/beta hydrolase domain-containing protein

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSWQSRVACWLLRWQFRPETLRPVLDPARARRFTDLRMRTIVPRRAPSGYRLRQCYGAGDAPLRGEWLERTDVPAGGATG
PTLLYFHGGGYYFCSTKTHRALVFGLTKRARVRSFSLDYRLAPENRFPAALDDALAAYRRLIALGTRPESIVLGGDSAGG
GLALATLVALRDAGEPLPAGAILFSPWTDLAGSGDTLRTHDGIDPMFAGAALPKAAKLYLGDTPATHPYASPLYADFSGL
PPLYIQVGSTEVLLDDSRRVADKARAAGVPVEIEIWPGMPHVWQLYTPMLPESRDALDRAAAFLRRVAVERAVQRVGEPS
IA

Sequences:

>Translated_322_residues
MSWQSRVACWLLRWQFRPETLRPVLDPARARRFTDLRMRTIVPRRAPSGYRLRQCYGAGDAPLRGEWLERTDVPAGGATG
PTLLYFHGGGYYFCSTKTHRALVFGLTKRARVRSFSLDYRLAPENRFPAALDDALAAYRRLIALGTRPESIVLGGDSAGG
GLALATLVALRDAGEPLPAGAILFSPWTDLAGSGDTLRTHDGIDPMFAGAALPKAAKLYLGDTPATHPYASPLYADFSGL
PPLYIQVGSTEVLLDDSRRVADKARAAGVPVEIEIWPGMPHVWQLYTPMLPESRDALDRAAAFLRRVAVERAVQRVGEPS
IA
>Mature_321_residues
SWQSRVACWLLRWQFRPETLRPVLDPARARRFTDLRMRTIVPRRAPSGYRLRQCYGAGDAPLRGEWLERTDVPAGGATGP
TLLYFHGGGYYFCSTKTHRALVFGLTKRARVRSFSLDYRLAPENRFPAALDDALAAYRRLIALGTRPESIVLGGDSAGGG
LALATLVALRDAGEPLPAGAILFSPWTDLAGSGDTLRTHDGIDPMFAGAALPKAAKLYLGDTPATHPYASPLYADFSGLP
PLYIQVGSTEVLLDDSRRVADKARAAGVPVEIEIWPGMPHVWQLYTPMLPESRDALDRAAAFLRRVAVERAVQRVGEPSI
A

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=151, Percent_Identity=33.112582781457, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786682, Length=306, Percent_Identity=29.0849673202614, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567059, Length=273, Percent_Identity=26.3736263736264, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 35225; Mature: 35094

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQSRVACWLLRWQFRPETLRPVLDPARARRFTDLRMRTIVPRRAPSGYRLRQCYGAGD
CCCHHHHEEEEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
APLRGEWLERTDVPAGGATGPTLLYFHGGGYYFCSTKTHRALVFGLTKRARVRSFSLDYR
CCCCCCHHHHCCCCCCCCCCCEEEEEECCEEEEECCCCCEEEEEECCCHHHHEEEECCEE
LAPENRFPAALDDALAAYRRLIALGTRPESIVLGGDSAGGGLALATLVALRDAGEPLPAG
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
AILFSPWTDLAGSGDTLRTHDGIDPMFAGAALPKAAKLYLGDTPATHPYASPLYADFSGL
EEEECCCHHCCCCCCCEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHCCCCC
PPLYIQVGSTEVLLDDSRRVADKARAAGVPVEIEIWPGMPHVWQLYTPMLPESRDALDRA
CCEEEEECCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
AAFLRRVAVERAVQRVGEPSIA
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SWQSRVACWLLRWQFRPETLRPVLDPARARRFTDLRMRTIVPRRAPSGYRLRQCYGAGD
CCHHHHEEEEEEEECCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
APLRGEWLERTDVPAGGATGPTLLYFHGGGYYFCSTKTHRALVFGLTKRARVRSFSLDYR
CCCCCCHHHHCCCCCCCCCCCEEEEEECCEEEEECCCCCEEEEEECCCHHHHEEEECCEE
LAPENRFPAALDDALAAYRRLIALGTRPESIVLGGDSAGGGLALATLVALRDAGEPLPAG
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCC
AILFSPWTDLAGSGDTLRTHDGIDPMFAGAALPKAAKLYLGDTPATHPYASPLYADFSGL
EEEECCCHHCCCCCCCEECCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHCCCCC
PPLYIQVGSTEVLLDDSRRVADKARAAGVPVEIEIWPGMPHVWQLYTPMLPESRDALDRA
CCEEEEECCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHH
AAFLRRVAVERAVQRVGEPSIA
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]