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The map label for this gene is glmS [H]

Identifier: 161523660

GI number: 161523660

Start: 523400

End: 524407

Strand: Direct

Name: glmS [H]

Synonym: Bmul_0480

Alternate gene names: 161523660

Gene position: 523400-524407 (Clockwise)

Preceding gene: 161523659

Following gene: 161523661

Centisome position: 15.18

GC content: 72.02

Gene sequence:

>1008_bases
ATGCTTAACGAAGCGCGCGAGTCCGCCCGGGTCGTCGCCGCGCAGCTTGCCGATACGACGCGCGTCGAAGCGCTCGCCGG
CCAGCTGATGGATCATCCGCCGGCCGTCGCGCTGACGGTCGCACGCGGCAGCTCCGATCATGCCGCGAGCTATTTCGCGA
GCCTGACGATGAGCCGCCTCGGCGTGCCGGTCGCGTCGCTGCCGATGTCGGTCGCGACGCTGCAGCAGGCGCCGCTGAAG
GTGCAGGACCAGCTCGCGATCGCGTTCTCGCAGTCGGGCAAGAGTCCCGATCTCGTCAATACGATGACCGCGCTGCGCGA
AGCCGGCGCGCGCACGGTGGCGGCCGTGAACGTGCTGCCGTCGCCGCTCGCCGACGCATGCGAGCACCAGTTGCCGCTGT
TGGCCGGCCCCGAGCTGTCGGTCGCGGCGACGAAGAGCTACATCGCGATGCTCTCGCTGTCCGCGCAGATCGTCGCGTTC
TGGCAGCGCGACGCCGCACTGATGACGGCGCTGCGCGGGCTGCCCGACGTGCTCGCGCGCGCGGGCACGCTCGACTGGTC
GGCGGCCGTCGCCGCGCTCGCCGGCGTCGAGCGGATGATCGTGATCGGCCGCGGCCTCGGCCTCGCGATCGCGCAGGAAG
CCGCGCTGAAGCTGAAGGAAACGTCCGGCATCCAGGCCGAGGCGTTTTCGAGCGCGGAGGTGCGTCACGGCCCGATGGAG
CTGATCGACCGCGACTACCCGCTGCTCGTGTTCGCGCCGCCGGGCCCCGAGCAGGCCGGCCTGCTGCAGCTCGCCGACGA
CATGCGCGCCCGCGGCGCGGCCGTGCTCGTCGCCGCGCCCGCCGGCACGCCGGGTGCGACGCTGCCGCTCGCATCGTCCG
CCCATCCGGCGCTCGACCCGATCGCCGCCATTCTTTCGTTCTACGTGATGGCGGCCGAGCTTGCCGTCGCGCGCGGCCGC
AATCCCGACACGCCGCGCCACCTGAACAAAGTCACCGAAACGCACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGCCTCGAGCGCGGCGCGTGGGCCGACCTCGTCGTGTTCGATCGCGACCTGAACCTCACCGCGACCTACGTCGA
AGGAGAATCGATTGTCGAAT

Downstream 100 bases:

>100_bases
TAGCCGAGACAGCCGATGAGACGCGCCGAGGAGTCCCAGTTGAAGAGTTCCACCCACGATCAGATCGTCCTGCTCGCCCC
GCTGACGGGGCCGATCGTCG

Product: glutamine--fructose-6-phosphate transaminase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLNEARESARVVAAQLADTTRVEALAGQLMDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMTALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAF
WQRDAALMTALRGLPDVLARAGTLDWSAAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLADDMRARGAAVLVAAPAGTPGATLPLASSAHPALDPIAAILSFYVMAAELAVARGR
NPDTPRHLNKVTETH

Sequences:

>Translated_335_residues
MLNEARESARVVAAQLADTTRVEALAGQLMDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMTALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAF
WQRDAALMTALRGLPDVLARAGTLDWSAAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLADDMRARGAAVLVAAPAGTPGATLPLASSAHPALDPIAAILSFYVMAAELAVARGR
NPDTPRHLNKVTETH
>Mature_335_residues
MLNEARESARVVAAQLADTTRVEALAGQLMDHPPAVALTVARGSSDHAASYFASLTMSRLGVPVASLPMSVATLQQAPLK
VQDQLAIAFSQSGKSPDLVNTMTALREAGARTVAAVNVLPSPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAF
WQRDAALMTALRGLPDVLARAGTLDWSAAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
LIDRDYPLLVFAPPGPEQAGLLQLADDMRARGAAVLVAAPAGTPGATLPLASSAHPALDPIAAILSFYVMAAELAVARGR
NPDTPRHLNKVTETH

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=326, Percent_Identity=26.3803680981595, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI205277386, Length=325, Percent_Identity=25.8461538461538, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1790167, Length=317, Percent_Identity=28.7066246056782, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17539970, Length=333, Percent_Identity=25.8258258258258, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=311, Percent_Identity=25.7234726688103, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17532897, Length=311, Percent_Identity=25.7234726688103, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322745, Length=308, Percent_Identity=25.3246753246753, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357745, Length=355, Percent_Identity=23.3802816901408, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 34743; Mature: 34743

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEARESARVVAAQLADTTRVEALAGQLMDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLAIAFSQSGKSPDLVNTMTALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAFWQRDAALMTALRGLPDVLAR
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
AGTLDWSAAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
CCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLADDMRARGAAVLVAAPAGTPGATLPLASSAHPALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
IAAILSFYVMAAELAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MLNEARESARVVAAQLADTTRVEALAGQLMDHPPAVALTVARGSSDHAASYFASLTMSRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
GVPVASLPMSVATLQQAPLKVQDQLAIAFSQSGKSPDLVNTMTALREAGARTVAAVNVLP
CCCHHHHCHHHHHHHHCCCCHHHHEEEEECCCCCCCHHHHHHHHHHHCCCHHEEEECCCC
SPLADACEHQLPLLAGPELSVAATKSYIAMLSLSAQIVAFWQRDAALMTALRGLPDVLAR
CHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
AGTLDWSAAVAALAGVERMIVIGRGLGLAIAQEAALKLKETSGIQAEAFSSAEVRHGPME
CCCCCHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHCCCCHH
LIDRDYPLLVFAPPGPEQAGLLQLADDMRARGAAVLVAAPAGTPGATLPLASSAHPALDP
HHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCHHHH
IAAILSFYVMAAELAVARGRNPDTPRHLNKVTETH
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA