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The map label for this gene is tauC [H]

Identifier: 161523601

GI number: 161523601

Start: 460480

End: 461445

Strand: Direct

Name: tauC [H]

Synonym: Bmul_0421

Alternate gene names: 161523601

Gene position: 460480-461445 (Clockwise)

Preceding gene: 161523600

Following gene: 161523604

Centisome position: 13.35

GC content: 70.39

Gene sequence:

>966_bases
ATGGGCGAGCTCGCACGCCACGGCACCTCCGTCGGCCGCGGCCGGATCGGCATCTTGGACAGGCAGGACAGCATGAGCAC
GCACGATTCCTGGGCGGCCGATCGCGCGGCCGCGAGACTCGACCGACACGCGGGCGCGACACCGTCGCGCCGCGTATCGC
GCACCGCGCGCACGTCGCACCGCTATCGGCTGCCGGGGCACGGCAACACGGCTGTACTCAGCGCGGCGACGGTCGCGGCG
CTCGCCGTGCTCTGGTGGGTCGCGACGCATCGGCAGTGGCTGCCGCCGTTGTTCCTGCCTGCGCCCGAAGCCGTGTGGAC
TGCGTTCGTCGACGCATGGCACGGCCGCATCCAGGGCGGGCTGCCGCTGTCCGAGCATCTGCTATGGAGCGCCGCGCGCG
TATTCGGGGCGTTCTTGCTCGCGACCGTAATCGGCGTGCCGGCCGGCATCCTGATGGGCGTGAGCCGCATCGCGCGCGGC
GTGCTCGATCCGCTGCTCGAGTTCTACCGGCCGCTGCCGCCGCTCGCGTATTTGCCGCTCGTCGTGATCTGGTTCGGCAT
CGACGAGACCGCGAAGCTCGTCGTGATCTTTCTCGCCTGCTTCGCGCCGATCGCGATGGCGGCCCGCGCCGGCGTGCGCG
CGGCGACCGTCGAGCAGATCAATGCCGCGTATTCGCTCGGCGGCAGTCTCGCGCAGATCGTGCGCCACGTCGTGCTGCCG
GCCGCGCTGCCCGAGATTCTGACGGGGCTGCGGATCGCGATCGGCTTCGGCTGGACGACGCTCGTCGCGGCCGAGATGGT
TGCCGCGACGGCCGGGCTCGGGCAGATGGTGTTGAACGCGTCGAGTTTTCTGCGCACCGACATCGTCGTGATGGGCATCC
TGATCATCGGTGCGATCGCGTGGCTGTTCGATCTCGCGATGCGCTGGATCGAGCGGCGCGTGGTGCCGTGGAAGGGGCGG
GCGTAA

Upstream 100 bases:

>100_bases
GCGATGCGCGCGCGGTGAAGTCGTCGCCGGAATTCATCGCATGGCGCGAGCGCCTGATCGCTTATCTGCATCGCGACGAA
ACGCTCGGCGAGGTCGCGTG

Downstream 100 bases:

>100_bases
GCGTCGCCGCGGCGCGGCCGCTCACTCGCCCATCGCAACGCCTTCCCGCCGCGGATCGGCGCCGCCGAACCACACCGTCT
GCCCCTGCACGTTCAACCGC

Product: binding-protein-dependent transport systems inner membrane component

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MGELARHGTSVGRGRIGILDRQDSMSTHDSWAADRAAARLDRHAGATPSRRVSRTARTSHRYRLPGHGNTAVLSAATVAA
LAVLWWVATHRQWLPPLFLPAPEAVWTAFVDAWHGRIQGGLPLSEHLLWSAARVFGAFLLATVIGVPAGILMGVSRIARG
VLDPLLEFYRPLPPLAYLPLVVIWFGIDETAKLVVIFLACFAPIAMAARAGVRAATVEQINAAYSLGGSLAQIVRHVVLP
AALPEILTGLRIAIGFGWTTLVAAEMVAATAGLGQMVLNASSFLRTDIVVMGILIIGAIAWLFDLAMRWIERRVVPWKGR
A

Sequences:

>Translated_321_residues
MGELARHGTSVGRGRIGILDRQDSMSTHDSWAADRAAARLDRHAGATPSRRVSRTARTSHRYRLPGHGNTAVLSAATVAA
LAVLWWVATHRQWLPPLFLPAPEAVWTAFVDAWHGRIQGGLPLSEHLLWSAARVFGAFLLATVIGVPAGILMGVSRIARG
VLDPLLEFYRPLPPLAYLPLVVIWFGIDETAKLVVIFLACFAPIAMAARAGVRAATVEQINAAYSLGGSLAQIVRHVVLP
AALPEILTGLRIAIGFGWTTLVAAEMVAATAGLGQMVLNASSFLRTDIVVMGILIIGAIAWLFDLAMRWIERRVVPWKGR
A
>Mature_320_residues
GELARHGTSVGRGRIGILDRQDSMSTHDSWAADRAAARLDRHAGATPSRRVSRTARTSHRYRLPGHGNTAVLSAATVAAL
AVLWWVATHRQWLPPLFLPAPEAVWTAFVDAWHGRIQGGLPLSEHLLWSAARVFGAFLLATVIGVPAGILMGVSRIARGV
LDPLLEFYRPLPPLAYLPLVVIWFGIDETAKLVVIFLACFAPIAMAARAGVRAATVEQINAAYSLGGSLAQIVRHVVLPA
ALPEILTGLRIAIGFGWTTLVAAEMVAATAGLGQMVLNASSFLRTDIVVMGILIIGAIAWLFDLAMRWIERRVVPWKGRA

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=248, Percent_Identity=50.8064516129032, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI87081802, Length=235, Percent_Identity=36.1702127659575, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789033, Length=165, Percent_Identity=31.5151515151515, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34599; Mature: 34468

Theoretical pI: Translated: 11.64; Mature: 11.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGELARHGTSVGRGRIGILDRQDSMSTHDSWAADRAAARLDRHAGATPSRRVSRTARTSH
CCCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
RYRLPGHGNTAVLSAATVAALAVLWWVATHRQWLPPLFLPAPEAVWTAFVDAWHGRIQGG
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
LPLSEHLLWSAARVFGAFLLATVIGVPAGILMGVSRIARGVLDPLLEFYRPLPPLAYLPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VVIWFGIDETAKLVVIFLACFAPIAMAARAGVRAATVEQINAAYSLGGSLAQIVRHVVLP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AALPEILTGLRIAIGFGWTTLVAAEMVAATAGLGQMVLNASSFLRTDIVVMGILIIGAIA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLFDLAMRWIERRVVPWKGRA
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GELARHGTSVGRGRIGILDRQDSMSTHDSWAADRAAARLDRHAGATPSRRVSRTARTSH
CCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC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HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]