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The map label for this gene is paaG [C]

Identifier: 161523573

GI number: 161523573

Start: 434596

End: 435483

Strand: Direct

Name: paaG [C]

Synonym: Bmul_0393

Alternate gene names: 161523573

Gene position: 434596-435483 (Clockwise)

Preceding gene: 161523572

Following gene: 161523574

Centisome position: 12.6

GC content: 69.14

Gene sequence:

>888_bases
ATGTTTGCGCGCGCGGGCTTGACTACACTCGATCCCACAGCCTCGACCCAGGAGCAGCGCATGGCCGATCTCGCCGCGTA
CGGCGGTTATCAAGCATTGAAGGTGACGCGCCGCGAACACGGCGTGCTCGACATCGTGATGAGCGGCGAGGGCGCGAATC
GCAGCGGTCTCGCGACGGCGAACGCGCAGATGCATCGCGAGCTCGCGGACATCTGGCGCGACGTCGATCGCGATCCCGAC
ACGCGCGTCGCCGTGATTCGCGGCGAAGGCAAGGGCTTCTCGGCGGGCGGCGATCTCGCGCTCGTCGAAGCGATGGCCAA
CGACTACGACGTGCGCGCCCGCGTGTGGCGCGAAGCGCGCGACCTCGTCTACAACGTGATCAACTGCAGCAAGCCGATCG
TGTCCGCGATGCACGGCCCGGCGGTCGGCGCGGGGCTCGTCGCGGGCCTGCTCGCCGACATCTCGATCGCCGCGAAGGAT
GCGCGGATCATCGACGGCCATACGCGGCTCGGCGTCGCGGCCGGCGATCACGCGGCGATCGTCTGGCCGCTGCTGTGCGG
GATGGCGAAGGCGAAGTACTACCTGATGCTCTGCGAGCCCGTGAGCGGCGAAGAGGCGGAGCGCATCGGCCTCGTGTCGC
TCGCGGTCGAGCCGGCCGATCTGTTGCCGAAGGCCTACGAAGTGGCCGAGCGGCTCGCGAACGGGTCGCAGTCGGCGATC
CGCTGGACGAAGTACGCGCTCAACAACTGGCTGCGCACGGCCGGGCCGACCTTCGATACGTCGCTCGCGCTGGAATTCAT
GGGCTTTTCGGGGCCCGACGTGCAGGAGGGCCTTCGTTCGCTGCGCGAGCGGCGCCCGCCCGCGTTTCCCGGCGACGCGC
CGTTCTGA

Upstream 100 bases:

>100_bases
GCGATCGAGCAATCGGTCGCGCCGCCCGACGGCGTCGCGTGACGCATGCGGTGTCCGGCGACGCACGGTCGCCGGGCCGG
CCCGCGCCGGGTTTCGCCCG

Downstream 100 bases:

>100_bases
CGCGCGCTATGATCGAAACACGCGATCGCGCTCGGATGCCGGCCGCGTGCTCCCCAGTCCAATCAGGATGCCCGTATGAC
GACCGATGCCTCCGGCTCCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MFARAGLTTLDPTASTQEQRMADLAAYGGYQALKVTRREHGVLDIVMSGEGANRSGLATANAQMHRELADIWRDVDRDPD
TRVAVIRGEGKGFSAGGDLALVEAMANDYDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKD
ARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLANGSQSAI
RWTKYALNNWLRTAGPTFDTSLALEFMGFSGPDVQEGLRSLRERRPPAFPGDAPF

Sequences:

>Translated_295_residues
MFARAGLTTLDPTASTQEQRMADLAAYGGYQALKVTRREHGVLDIVMSGEGANRSGLATANAQMHRELADIWRDVDRDPD
TRVAVIRGEGKGFSAGGDLALVEAMANDYDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKD
ARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLANGSQSAI
RWTKYALNNWLRTAGPTFDTSLALEFMGFSGPDVQEGLRSLRERRPPAFPGDAPF
>Mature_295_residues
MFARAGLTTLDPTASTQEQRMADLAAYGGYQALKVTRREHGVLDIVMSGEGANRSGLATANAQMHRELADIWRDVDRDPD
TRVAVIRGEGKGFSAGGDLALVEAMANDYDVRARVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKD
ARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLANGSQSAI
RWTKYALNNWLRTAGPTFDTSLALEFMGFSGPDVQEGLRSLRERRPPAFPGDAPF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=159, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787660, Length=260, Percent_Identity=30, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787659, Length=265, Percent_Identity=28.6792452830189, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI221142681, Length=212, Percent_Identity=29.7169811320755, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788597, Length=263, Percent_Identity=23.1939163498099, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17534483, Length=230, Percent_Identity=28.2608695652174, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=236, Percent_Identity=26.271186440678, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=216, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17535521, Length=192, Percent_Identity=26.0416666666667, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653139, Length=239, Percent_Identity=28.0334728033473, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129971, Length=238, Percent_Identity=26.0504201680672, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24653477, Length=238, Percent_Identity=26.0504201680672, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24654903, Length=227, Percent_Identity=24.6696035242291, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922422, Length=262, Percent_Identity=24.4274809160305, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31722; Mature: 31722

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARAGLTTLDPTASTQEQRMADLAAYGGYQALKVTRREHGVLDIVMSGEGANRSGLATA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHEEEHHHHCCEEEEEEECCCCCCCCCCHH
NAQMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLALVEAMANDYDVRARVWREAR
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
DLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
HHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHH
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLANGSQSAI
HHHHHHHHHHCEEEEEEECCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHH
RWTKYALNNWLRTAGPTFDTSLALEFMGFSGPDVQEGLRSLRERRPPAFPGDAPF
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFARAGLTTLDPTASTQEQRMADLAAYGGYQALKVTRREHGVLDIVMSGEGANRSGLATA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHEEEHHHHCCEEEEEEECCCCCCCCCCHH
NAQMHRELADIWRDVDRDPDTRVAVIRGEGKGFSAGGDLALVEAMANDYDVRARVWREAR
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
DLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIAAKDARIIDGHTRLGVAAGDHAAI
HHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHH
VWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVEPADLLPKAYEVAERLANGSQSAI
HHHHHHHHHHCEEEEEEECCCCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHH
RWTKYALNNWLRTAGPTFDTSLALEFMGFSGPDVQEGLRSLRERRPPAFPGDAPF
HHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA