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The map label for this gene is oxyR [H]

Identifier: 161523550

GI number: 161523550

Start: 406875

End: 407792

Strand: Direct

Name: oxyR [H]

Synonym: Bmul_0370

Alternate gene names: 161523550

Gene position: 406875-407792 (Clockwise)

Preceding gene: 161523543

Following gene: 161523560

Centisome position: 11.8

GC content: 66.34

Gene sequence:

>918_bases
ATGGCCCTGACCCTCAGACAGCTCAAGTACTTCGTCGCGACCGCCGAGCTCGGTCAAATCTCGCAGGCCGCGATCCAGCT
GACGATCTCGCAGTCCGCGGTGACGAGCGCGATCAAGGAACTGGAAGACAGCCTTGGCACGCAGCTGTTCCTGCGCACGT
CGGCAGGCGTCACGCTGACCGATACGGGGCGGCGCTTCCTGAATCACGCGTACGCGATCCTCTCGTCGGTCGACGAGGCG
ATGCGGATCCCGAACCTCGAAAGCACGCTGACGGGCACGCTCGCGATCGCCGCGAGCTACACGGTGCTCGGCTACTTCCT
GCCGCATCACGTGCTGCGCCTGAACACGCTCTATCCGCGGTTGACGATCCATCTGCACGAGCTGAACCGCGAGTCGATCG
AGGAAGGGCTGATCGCGGGCCGCTATGACATGGCCGTGCTGCTGACCTCGAACGTGTCGAACCCCGAGCTCGTACTCGAG
CCGGTGATCCATTCGGTGCGCCGGCTGTGGGTCGGCGCGCACCATCCGCTGCTCAGGCGCGAGAGCGTCACGTTCGCCGA
GGTCGCGCGCGAACCGTTCGTGATGCTGACGGTCGACGAGGCCGGGCAAACGGCGATGCGCTACTGGAACGAGACACCGT
ATCGGCCGAACGTGATCCTGCGCACGTCGTCGGTCGAGGCCGTGCGCAGCATGGTCGCGAACGGCACCGGCGTCGCGGTG
CTGTCCGACATGGTGTATCGGCCGTGGTCGCTGGAAGGGCGGCGCATCGAGACGATCCTGCTGCGCGACCCGGTACCGCC
GATGAGCGTCGGCCTCGCGTGGCGCAAGAACATCGAGCTGAGCCCCGCGATGCATGCGGTGCGCGACTATTTCCGGCACA
CCTTCATGGAGCCGAGGACGATCGGCGGCGGCGCGTGA

Upstream 100 bases:

>100_bases
CCGCCGCAGCGGGCGCGGCAGGGTTTTCACGAGGCCGGCTTCTGCGTCGCGGCACGGTTGATATGATGTTTATCGCGCCT
CCATCAGTTTTCCGTCGACC

Downstream 100 bases:

>100_bases
GTGCCGCCGTGCCGTGCAGGTATGCGAACCGTACGGCAACGAAAAAGCCGGGACACGTCCCGGCTTTTTCATCGGGCGGG
CGAACCCGCGGTGCGCTGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTSAGVTLTDTGRRFLNHAYAILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSVRRLWVGAHHPLLRRESVTFAEVAREPFVMLTVDEAGQTAMRYWNETPYRPNVILRTSSVEAVRSMVANGTGVAV
LSDMVYRPWSLEGRRIETILLRDPVPPMSVGLAWRKNIELSPAMHAVRDYFRHTFMEPRTIGGGA

Sequences:

>Translated_305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTSAGVTLTDTGRRFLNHAYAILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSVRRLWVGAHHPLLRRESVTFAEVAREPFVMLTVDEAGQTAMRYWNETPYRPNVILRTSSVEAVRSMVANGTGVAV
LSDMVYRPWSLEGRRIETILLRDPVPPMSVGLAWRKNIELSPAMHAVRDYFRHTFMEPRTIGGGA
>Mature_304_residues
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTSAGVTLTDTGRRFLNHAYAILSSVDEAM
RIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEP
VIHSVRRLWVGAHHPLLRRESVTFAEVAREPFVMLTVDEAGQTAMRYWNETPYRPNVILRTSSVEAVRSMVANGTGVAVL
SDMVYRPWSLEGRRIETILLRDPVPPMSVGLAWRKNIELSPAMHAVRDYFRHTFMEPRTIGGGA

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=30.6049822064057, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI157672245, Length=301, Percent_Identity=28.2392026578073, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=27.681660899654, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=28.2868525896414, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787879, Length=302, Percent_Identity=33.112582781457, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=27.7966101694915, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788297, Length=259, Percent_Identity=28.957528957529, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788887, Length=305, Percent_Identity=26.5573770491803, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787601, Length=185, Percent_Identity=28.1081081081081, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788748, Length=149, Percent_Identity=29.5302013422819, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=196, Percent_Identity=30.6122448979592, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786401, Length=317, Percent_Identity=26.1829652996845, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=303, Percent_Identity=23.7623762376238, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=278, Percent_Identity=23.7410071942446, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787806, Length=145, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=289, Percent_Identity=27.3356401384083, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34033; Mature: 33902

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTSAGVTLT
CCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEEE
DTGRRFLNHAYAILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSVRRLWVGAHHPLLRR
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHC
ESVTFAEVAREPFVMLTVDEAGQTAMRYWNETPYRPNVILRTSSVEAVRSMVANGTGVAV
CCCHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCHHH
LSDMVYRPWSLEGRRIETILLRDPVPPMSVGLAWRKNIELSPAMHAVRDYFRHTFMEPRT
HHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
IGGGA
CCCCC
>Mature Secondary Structure 
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDSLGTQLFLRTSAGVTLT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEEE
DTGRRFLNHAYAILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
LTIHLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSVRRLWVGAHHPLLRR
EEEEEECCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHC
ESVTFAEVAREPFVMLTVDEAGQTAMRYWNETPYRPNVILRTSSVEAVRSMVANGTGVAV
CCCHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCHHH
LSDMVYRPWSLEGRRIETILLRDPVPPMSVGLAWRKNIELSPAMHAVRDYFRHTFMEPRT
HHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
IGGGA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]