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The map label for this gene is macB [H]

Identifier: 161523384

GI number: 161523384

Start: 227176

End: 228342

Strand: Reverse

Name: macB [H]

Synonym: Bmul_0204

Alternate gene names: 161523384

Gene position: 228342-227176 (Counterclockwise)

Preceding gene: 161523385

Following gene: 161523382

Centisome position: 6.62

GC content: 67.61

Gene sequence:

>1167_bases
ATGGCGATTCCGCTCACCTACATCGCGCGCAATCTGTGGGCGCGCCGCCTCACCACCGCGCTGACCGCCGGCGGGATGGC
GCTCGTGATCTTCGTGTTCGCGACCGTGCTGATGCTCGACGCCGGGCTCACGCAGACGCTCGTGTCGACCGGCGAGCCCG
ACAATGTCGTCGTGATCCGCAAGGGCGCCGAGACCGAAATCCAGAGCGCGATCGATCATCAGCAGGCGAACGCGCTCGAG
ATGCATCCGGCCGTCGCGCTCGGCGCCGACGGCCGGCCGCTCGTGTCGAAGGAAGCGGTCGTGCTGATCTCGCTCGTGAA
GACGTCGACCGGCAAACCGTCGAACGTCGTGATCCGCGGCGTCTCGCCGGCCGGGCTCGCGCTGCGCCCGCGCGTGCAGC
TCAAGGCGGGCCGCATGTTCGCGCCGGGCTCGTCGGAAATCATCGTCGGCAGCGCGGTCGCGAAAGGCTTCAGCGGCACG
CAGCTCGGCGACCGTCTGCATTTCGCGCAGCGCGACTGGACCATCGTCGGCGTGTTCGACGCGGGCGGCAGCGGCTTCGA
TTCGGAAATCTGGGGCGACGTCGATCAGCTGATGCAGTCGTTCCGGCGCACGAGCTATTCGTCGATGGTGCTGCGCATTC
CGAGCGCGGACGGCTTCGCGCGCTTCAAGGCCGACATCGACGTCGATCCGCGGCTGACCGACGAAGCCAAGCGCGAGCAG
ACGTTCTACGGCGATCAGTCGAAGGCGCTGTCGACCTTCATCAACATCCTCGGGATCACGCTGTCGACGATCTTCTCGAT
CGCCGCGATGATCGGCGCGACGATCACGATGTATGCGTCGGTCGCGAACCGCACCGCCGAGATCGGCACGCTGCGCGCGC
TCGGCTTCAAGCGCGCCAACGTGCTCGCGGCGTTCCTGCTCGAAGCGCTGCTGCTCGGCTTCGTCGGCGGCGTCGCAGGG
CTCGCCTGCGCGTCGCTGATGCAGTTCGCGTCGTTCTCGACGACCAACTTCCAGACCTTCTCGGACCTGTCGTTCCGCTT
CGTGCTGACGCCGGCGATCGTCGTCAAGACGCTGCTGTTCTCGCTCGTGATGGGGCTCGTCGGCGGCTTCCTGCCGGCGC
TGCGCGCCGCGCGGCTCAATATCGTCGACGCGTTGCGCGCGCGGTGA

Upstream 100 bases:

>100_bases
TCGGTCGCGGTCGGCGTGGCGGCCGCGCTGGTGCCCGCGTGGCAGGCCGCGCGCGTGCGTGTCGTGGAAGGCCTGCGGGC
GATCGGCTGACGGGCGCGGC

Downstream 100 bases:

>100_bases
TGCAAGGCCCGCGCGCGCACGCGCTCAGCACGCTTCCGTCGACGGCGGCAGCTCGCCGCGCGCCAGCGCGAGTGCGTGGT
CGCGCACGTCGTCCGGCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAIPLTYIARNLWARRLTTALTAGGMALVIFVFATVLMLDAGLTQTLVSTGEPDNVVVIRKGAETEIQSAIDHQQANALE
MHPAVALGADGRPLVSKEAVVLISLVKTSTGKPSNVVIRGVSPAGLALRPRVQLKAGRMFAPGSSEIIVGSAVAKGFSGT
QLGDRLHFAQRDWTIVGVFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMVLRIPSADGFARFKADIDVDPRLTDEAKREQ
TFYGDQSKALSTFINILGITLSTIFSIAAMIGATITMYASVANRTAEIGTLRALGFKRANVLAAFLLEALLLGFVGGVAG
LACASLMQFASFSTTNFQTFSDLSFRFVLTPAIVVKTLLFSLVMGLVGGFLPALRAARLNIVDALRAR

Sequences:

>Translated_388_residues
MAIPLTYIARNLWARRLTTALTAGGMALVIFVFATVLMLDAGLTQTLVSTGEPDNVVVIRKGAETEIQSAIDHQQANALE
MHPAVALGADGRPLVSKEAVVLISLVKTSTGKPSNVVIRGVSPAGLALRPRVQLKAGRMFAPGSSEIIVGSAVAKGFSGT
QLGDRLHFAQRDWTIVGVFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMVLRIPSADGFARFKADIDVDPRLTDEAKREQ
TFYGDQSKALSTFINILGITLSTIFSIAAMIGATITMYASVANRTAEIGTLRALGFKRANVLAAFLLEALLLGFVGGVAG
LACASLMQFASFSTTNFQTFSDLSFRFVLTPAIVVKTLLFSLVMGLVGGFLPALRAARLNIVDALRAR
>Mature_387_residues
AIPLTYIARNLWARRLTTALTAGGMALVIFVFATVLMLDAGLTQTLVSTGEPDNVVVIRKGAETEIQSAIDHQQANALEM
HPAVALGADGRPLVSKEAVVLISLVKTSTGKPSNVVIRGVSPAGLALRPRVQLKAGRMFAPGSSEIIVGSAVAKGFSGTQ
LGDRLHFAQRDWTIVGVFDAGGSGFDSEIWGDVDQLMQSFRRTSYSSMVLRIPSADGFARFKADIDVDPRLTDEAKREQT
FYGDQSKALSTFINILGITLSTIFSIAAMIGATITMYASVANRTAEIGTLRALGFKRANVLAAFLLEALLLGFVGGVAGL
ACASLMQFASFSTTNFQTFSDLSFRFVLTPAIVVKTLLFSLVMGLVGGFLPALRAARLNIVDALRAR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=128, Percent_Identity=36.71875, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41314; Mature: 41182

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPLTYIARNLWARRLTTALTAGGMALVIFVFATVLMLDAGLTQTLVSTGEPDNVVVIR
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE
KGAETEIQSAIDHQQANALEMHPAVALGADGRPLVSKEAVVLISLVKTSTGKPSNVVIRG
CCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCHHHEEEEHHCCCCCCCCEEEEE
VSPAGLALRPRVQLKAGRMFAPGSSEIIVGSAVAKGFSGTQLGDRLHFAQRDWTIVGVFD
CCCCCCEECCCEEEECCCEECCCCCCEEEEHHHHCCCCCCCHHHHHHHCCCCEEEEEEEE
AGGSGFDSEIWGDVDQLMQSFRRTSYSSMVLRIPSADGFARFKADIDVDPRLTDEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHH
TFYGDQSKALSTFINILGITLSTIFSIAAMIGATITMYASVANRTAEIGTLRALGFKRAN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAFLLEALLLGFVGGVAGLACASLMQFASFSTTNFQTFSDLSFRFVLTPAIVVKTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
SLVMGLVGGFLPALRAARLNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIPLTYIARNLWARRLTTALTAGGMALVIFVFATVLMLDAGLTQTLVSTGEPDNVVVIR
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEE
KGAETEIQSAIDHQQANALEMHPAVALGADGRPLVSKEAVVLISLVKTSTGKPSNVVIRG
CCCCHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCHHHEEEEHHCCCCCCCCEEEEE
VSPAGLALRPRVQLKAGRMFAPGSSEIIVGSAVAKGFSGTQLGDRLHFAQRDWTIVGVFD
CCCCCCEECCCEEEECCCEECCCCCCEEEEHHHHCCCCCCCHHHHHHHCCCCEEEEEEEE
AGGSGFDSEIWGDVDQLMQSFRRTSYSSMVLRIPSADGFARFKADIDVDPRLTDEAKREQ
CCCCCCCHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHH
TFYGDQSKALSTFINILGITLSTIFSIAAMIGATITMYASVANRTAEIGTLRALGFKRAN
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAFLLEALLLGFVGGVAGLACASLMQFASFSTTNFQTFSDLSFRFVLTPAIVVKTLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHH
SLVMGLVGGFLPALRAARLNIVDALRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA