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The map label for this gene is gmhA [H]

Identifier: 161523378

GI number: 161523378

Start: 221426

End: 222010

Strand: Direct

Name: gmhA [H]

Synonym: Bmul_0198

Alternate gene names: 161523378

Gene position: 221426-222010 (Clockwise)

Preceding gene: 161523377

Following gene: 161523379

Centisome position: 6.42

GC content: 70.43

Gene sequence:

>585_bases
ATGTCAGTCGAACGTATTCAGCAACATTTCCGCGACAGTGCCGCGCTTCATGCGCAAGCCGCCGACGCGCTGTCGCTGCC
GATCGCAGCCGCGGTCGACGCGATGTTCGCCGCACTGGCGAACGGCAACAAGATCGTCGCGTGCGGCGACGGCCCGTCAG
CCGCCGCAGCGCACTACCTCGCCGTGTCGCTGGTCGGCGGCTTCGAGCGCGAGCGCCCGGGCCTGCCCGCGATCGCGCTG
GCCACCGATGCGTCGCAGGCCGGCCTCGCCGGCGCGGCGGCCGCCGATCAACTGTTCGCGCAACAGGTGCGCGTGCTCGG
GCAGACGGGCGACATCCTGCTGGTGCTCGATTCGGGCGGTGCGTCGCCGCGCGTGCTCGCGGCGATCGACGAAGCGCACG
AGCGCGAGATGACTGTCGTCGCGCTGACGGGCGGCGGCGGCCATGCAGTCGCGGCCGCGCTGTCCGACACCGATATTGCG
ATCAGCGTGCCCGCCGTCCGGGCGGCGCGCATTCACGAAGTCCATCTGCTGACCATCCACTGCCTGTGCGACGGCATCGA
CGCGATGCTGCTGGGTGAGGATTGA

Upstream 100 bases:

>100_bases
GACCGCGGGACACGGTGCCGGAGTACGGTAAACTCGCCGCACTCACGATGTGTCGCGCGACGTGCCGAAGCGTGCTGCGC
GCCCAGTTCACCAGGAATCG

Downstream 100 bases:

>100_bases
ACGAAGGAGAGCCGTCGATGAATCAAAGCCGCGTCAAACAGACGCTCGTCAGAACCACGCTGCTCGCCGCGCTGACGGCG
GGGCTCGCCGTGTCGCTGCA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSVERIQQHFRDSAALHAQAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIAL
ATDASQAGLAGAAAADQLFAQQVRVLGQTGDILLVLDSGGASPRVLAAIDEAHEREMTVVALTGGGGHAVAAALSDTDIA
ISVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED

Sequences:

>Translated_194_residues
MSVERIQQHFRDSAALHAQAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIAL
ATDASQAGLAGAAAADQLFAQQVRVLGQTGDILLVLDSGGASPRVLAAIDEAHEREMTVVALTGGGGHAVAAALSDTDIA
ISVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED
>Mature_193_residues
SVERIQQHFRDSAALHAQAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYLAVSLVGGFERERPGLPAIALA
TDASQAGLAGAAAADQLFAQQVRVLGQTGDILLVLDSGGASPRVLAAIDEAHEREMTVVALTGGGGHAVAAALSDTDIAI
SVPAVRAARIHEVHLLTIHCLCDGIDAMLLGED

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=44.4444444444444, Blast_Score=156, Evalue=8e-40,
Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=31.2169312169312, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 19568; Mature: 19437

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVERIQQHFRDSAALHAQAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AVSLVGGFERERPGLPAIALATDASQAGLAGAAAADQLFAQQVRVLGQTGDILLVLDSGG
HHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
ASPRVLAAIDEAHEREMTVVALTGGGGHAVAAALSDTDIAISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCHHHHEEEEEEEEEEE
CLCDGIDAMLLGED
EECCCCCEEEECCC
>Mature Secondary Structure 
SVERIQQHFRDSAALHAQAADALSLPIAAAVDAMFAALANGNKIVACGDGPSAAAAHYL
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
AVSLVGGFERERPGLPAIALATDASQAGLAGAAAADQLFAQQVRVLGQTGDILLVLDSGG
HHHHHCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
ASPRVLAAIDEAHEREMTVVALTGGGGHAVAAALSDTDIAISVPAVRAARIHEVHLLTIH
CCCEEEEEEHHHCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCHHHHEEEEEEEEEEE
CLCDGIDAMLLGED
EECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA