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The map label for this gene is ycbL [H]

Identifier: 161523374

GI number: 161523374

Start: 217961

End: 218605

Strand: Reverse

Name: ycbL [H]

Synonym: Bmul_0194

Alternate gene names: 161523374

Gene position: 218605-217961 (Counterclockwise)

Preceding gene: 161523376

Following gene: 161523373

Centisome position: 6.34

GC content: 66.98

Gene sequence:

>645_bases
ATGAAAGTCACGCTCATTCCGGTCACGCCGTTCCAGCAGAACTGCTCGCTGCTCGTCTGCGAGAAGACGGGCCGCGCCGC
CGTCGTCGATCCGGGCGGCGATCTCGAACGGATCGAACAGGAGATCGCGCGGCAGAACGTGCAGGTCGACAAGGTGCTGC
TCACGCACGGGCACATCGATCACTGCGCGGGCGCAAAGACGCTCGCGACGCACTACGGCGTGCCGATCGAAGGGCCGCAG
GAAGACGAGCGCTTCTGGATCGAGAAGCTGCCGACGCAGAGCGAGCGCTTCGGCTTCCCGGCCGCGGAAGCGTTCGAGCC
CGATCGCTGGCTGAACGACGGCGACACCGTGCAGTTCGGCGACGAGACGCTCGAGGTCTACCACTGCCCGGGCCATACGC
CGGGCCACGTCGTGTTCTTCAGTCGCGCGCATCGCGTCGCGATCGTCGGCGACGTGCTGTTCGCGGGCTCGATCGGCCGC
ACCGATTTCCCGCGCGGCAATCATGCGGACCTCGTCCGCTCGATCAAGGAGAAGCTGTGGCCGCTCGGCGACGACGTGAC
GTTCGTGCCGGGCCACGGCCCCGTGTCGACGTTCGGCGACGAGCGCCGCACGAATCCGTTCGTGTCGGACAAGGTGTTCG
GATGA

Upstream 100 bases:

>100_bases
GCTGCGGGATTGCCCGAACAACGGCCGTGCACGGCGCCGCGCGGCCGGCAGCACACGCGCCCGACCGGTACAATCGATCC
TTTTAGCCGCCGGTGCTTCC

Downstream 100 bases:

>100_bases
ACCAGACCGCGATTCCCGAAATCTACGTCAGCACCGACGTCGAGGCGGACGGCCCGATTCCCGGCCCGCACTCGATGCTG
AGCTTCGCGTCGGCCGCCTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLERIEQEIARQNVQVDKVLLTHGHIDHCAGAKTLATHYGVPIEGPQ
EDERFWIEKLPTQSERFGFPAAEAFEPDRWLNDGDTVQFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHADLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG

Sequences:

>Translated_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLERIEQEIARQNVQVDKVLLTHGHIDHCAGAKTLATHYGVPIEGPQ
EDERFWIEKLPTQSERFGFPAAEAFEPDRWLNDGDTVQFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHADLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
>Mature_214_residues
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLERIEQEIARQNVQVDKVLLTHGHIDHCAGAKTLATHYGVPIEGPQ
EDERFWIEKLPTQSERFGFPAAEAFEPDRWLNDGDTVQFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGR
TDFPRGNHADLVRSIKEKLWPLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=207, Percent_Identity=31.4009661835749, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=56.1320754716981, Blast_Score=267, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17538952, Length=192, Percent_Identity=31.25, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI221330176, Length=201, Percent_Identity=25.3731343283582, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23696; Mature: 23696

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLERIEQEIARQNVQVDKVLLTHGHID
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCHH
HCAGAKTLATHYGVPIEGPQEDERFWIEKLPTQSERFGFPAAEAFEPDRWLNDGDTVQFG
HHCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCHHCCCCCCCCCCCCEEEEC
DETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPRGNHADLVRSIKEKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVTLIPVTPFQQNCSLLVCEKTGRAAVVDPGGDLERIEQEIARQNVQVDKVLLTHGHID
CEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCHH
HCAGAKTLATHYGVPIEGPQEDERFWIEKLPTQSERFGFPAAEAFEPDRWLNDGDTVQFG
HHCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHCCCCCHHCCCCCCCCCCCCEEEEC
DETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPRGNHADLVRSIKEKLW
CCEEEEEECCCCCCCEEEEEECCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGDDVTFVPGHGPVSTFGDERRTNPFVSDKVFG
CCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]