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The map label for this gene is motA [H]

Identifier: 161523342

GI number: 161523342

Start: 182555

End: 183415

Strand: Direct

Name: motA [H]

Synonym: Bmul_0162

Alternate gene names: 161523342

Gene position: 182555-183415 (Clockwise)

Preceding gene: 161523341

Following gene: 161523343

Centisome position: 5.29

GC content: 65.62

Gene sequence:

>861_bases
GTGCTGATTATCGTAGGAACACTCGTGACGCTGTTGTCCGTCTTCGGCGGTTATGCGCTGGCGGGCGGGCATCTGGGCGC
GCTGGTCCAGCCCCTCGAAATCCTGATGATCGCGGGCGCCGGCATCGGCGCGTTCATCCTCGGCAACGGCAGCAAGACCA
TCAAGGCGACGGTGCGCGTACTGCCGACGCTGTTCAAGGGCTCGAAGTACACGAAGGACGTGTACATGGAGCTGATGGCG
CTGCTCTACGTGCTGCTCGCGAAGGCGCGCAAGGAAGGCACGCTGACGCTCGAGGCCGACATCGACGATCCGGAGAAGAG
CCCGATCTTCACGCAGTACCCGAAGATCCTCGCCGATCGCCACATCGTCGAATTCCTGACCGATTACCTGCGCCTGATGG
TCGGCGGCAACATGAACGCGTTCGAGATCGAGAGCCTGATGGACGAGGAGATCGAGACGCACCACGCCGAGGGCGAAGGC
CCCGCGCATGCGCTGATGCGCGTCGGCGACGCGATGCCGGCATTCGGGATCGTCGCGGCCGTGATGGGCGTCGTGCACAC
GATGGCGTCGGCCGACAAGCCGCCCGCGGTGCTCGGCGCGATGATCGCGCAGGCGCTGGTCGGCACGTTCCTCGGGATCC
TGCTGTCGTACGGGCTGATCGGGCCGCTCGCGAGCCTCGCGGAGCAGCGCGTGGCCGAGTCGACGAAGATGTTCCAGTGC
ATCAAGGTGACGATCCTCGCGAGCCTGAACGGCTATGCGCCGGCGATCGCGGTCGAGTTCGGCCGCAAGGTGCTGTTCTC
GCCGGAGCGCCCGTCGTTCGCGGAACTCGAAGAGCACGTGCGCCGCGTGAAGGCGAAATGA

Upstream 100 bases:

>100_bases
ACCGCCCGCCCACGCCCGTGCGGCCGCGAAAGTTTTCCTGCCCACTGCCGTAAACCACTTAACGGCGGTCTCCCCGCCGG
TCTTTCGTGAGGGACAGGCA

Downstream 100 bases:

>100_bases
CGCGGAGCGAGCGATGAGCAAGGGCAAGGAACGTGCGATCGTCGTCAAGCGGGTGGCCCCGCAGAAGAAGGGCCATCACG
GCGGCGCATGGAAGCTCGCG

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALVQPLEILMIAGAGIGAFILGNGSKTIKATVRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADRHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSPERPSFAELEEHVRRVKAK

Sequences:

>Translated_286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALVQPLEILMIAGAGIGAFILGNGSKTIKATVRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADRHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSPERPSFAELEEHVRRVKAK
>Mature_286_residues
MLIIVGTLVTLLSVFGGYALAGGHLGALVQPLEILMIAGAGIGAFILGNGSKTIKATVRVLPTLFKGSKYTKDVYMELMA
LLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADRHIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEG
PAHALMRVGDAMPAFGIVAAVMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
IKVTILASLNGYAPAIAVEFGRKVLFSPERPSFAELEEHVRRVKAK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=64.0845070422535, Blast_Score=383, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30641; Mature: 30641

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGTLVTLLSVFGGYALAGGHLGALVQPLEILMIAGAGIGAFILGNGSKTIKATVRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
LPTLFKGSKYTKDVYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSPERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCCHHHHHHCCHHCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIIVGTLVTLLSVFGGYALAGGHLGALVQPLEILMIAGAGIGAFILGNGSKTIKATVRV
CEEEHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
LPTLFKGSKYTKDVYMELMALLYVLLAKARKEGTLTLEADIDDPEKSPIFTQYPKILADR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
HIVEFLTDYLRLMVGGNMNAFEIESLMDEEIETHHAEGEGPAHALMRVGDAMPAFGIVAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHH
VMGVVHTMASADKPPAVLGAMIAQALVGTFLGILLSYGLIGPLASLAEQRVAESTKMFQC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTILASLNGYAPAIAVEFGRKVLFSPERPSFAELEEHVRRVKAK
HHHHHHHHCCCCCCHHHHHHCCHHCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]