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The map label for this gene is yafC [H]

Identifier: 161523309

GI number: 161523309

Start: 143045

End: 143929

Strand: Reverse

Name: yafC [H]

Synonym: Bmul_0129

Alternate gene names: 161523309

Gene position: 143929-143045 (Counterclockwise)

Preceding gene: 161523311

Following gene: 161523304

Centisome position: 4.17

GC content: 69.15

Gene sequence:

>885_bases
ATGGACAACCTGAACGGCATCGTCGCCTTCGTGCGCGCCGCCGACGCGCTGAGCTTCGTCGCGGCCGGCCGTACGCTCGG
CATCTCGGCGTCGGCGGTCGGCAAGACGATCGCGCGGCTCGAGCAGTCGCTCGGCGTGCGGCTGTTCAACCGCACCACGC
GCCGCATCACGCTGACCGACGAAGGGCGGCATTTCTACGAGCGCTGCCAGCGCATCCTCGAGGATCTTCGCGACGCGGAG
GCGACCGTGACGGCATCCGCGCAGCGCCCGCGCGGCAAGCTGCGCGTGAGCCTGCCGGTGATCGGCTACCGGTTCCTGCT
GCCGGTGCTGCCGGAATTCAGGCAGCGCTATCCGGACGTCGAGCTCGATCTGGATTTCAACGACCGGATGGTCGACGTCG
TCGAAGGCGGGTTCGATGCGGTGATCCGTAGCGGGCCGCTATCCGATTCGAGCCTGATGTCGCGGCGGCTCGGCCCGTTC
GCGTTCGTATTGTGCGCGACGCCCGCGTATCTCGCGCGGGCCGGCACACCGCGCGCGCCGTGCGATCTCGAAGCGCACGA
CTGCGTGCGCTACTGCTTCCCGACCACGGGCAAGCTGCAGGACTGGGCGCTCGCCGCGGACGACGGCACGCCGCTGAAGC
TGCGCACCGCGATGACGTGCAACAACATGGAAGCGCTGCGCGGCGCGGTGCTCGCGGGGCTCGGCATCGGCTACATGCCG
GACTTTCTCGCGCGCGATGCGCTCGAGCGCGGCGCACTCGTCACCGTGCTCGACGACTACCGGATCGCGCCGGGCCAGTT
CTCGATCGTCTGGCCGTCGAGCCGGCAGCTGTCGCCGAAGCTGCGCGTGTTCGTCGACTTTCTCTGCGAGCGGCTGTTCA
AGTAG

Upstream 100 bases:

>100_bases
CACAAGATAAATCCGATCCAATCCGCGAAAAACCACGCGAAGCTCCGCATATAACGGACTAGAATTCCGCAATCTGTCTT
CACTGGAGCGTGCTTCGTCG

Downstream 100 bases:

>100_bases
CGCGATCGCAGGCCGCGCCGATGCGCTCCGGCTGCGCGGCAGGCAGCAGCGCGTCGCTGTCGTCCTTGAGCCCGACGCCC
GTCAGCCCGAGCCGGCGCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDNLNGIVAFVRAADALSFVAAGRTLGISASAVGKTIARLEQSLGVRLFNRTTRRITLTDEGRHFYERCQRILEDLRDAE
ATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDVELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPF
AFVLCATPAYLARAGTPRAPCDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGAVLAGLGIGYMP
DFLARDALERGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFK

Sequences:

>Translated_294_residues
MDNLNGIVAFVRAADALSFVAAGRTLGISASAVGKTIARLEQSLGVRLFNRTTRRITLTDEGRHFYERCQRILEDLRDAE
ATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDVELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPF
AFVLCATPAYLARAGTPRAPCDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGAVLAGLGIGYMP
DFLARDALERGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFK
>Mature_294_residues
MDNLNGIVAFVRAADALSFVAAGRTLGISASAVGKTIARLEQSLGVRLFNRTTRRITLTDEGRHFYERCQRILEDLRDAE
ATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDVELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPF
AFVLCATPAYLARAGTPRAPCDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGAVLAGLGIGYMP
DFLARDALERGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=35.8885017421603, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=36.7697594501718, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1787128, Length=288, Percent_Identity=34.375, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=31.0580204778157, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=34.1296928327645, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.8041237113402, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789173, Length=294, Percent_Identity=27.2108843537415, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=30.3030303030303, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786508, Length=266, Percent_Identity=24.812030075188, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787879, Length=284, Percent_Identity=27.112676056338, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=301, Percent_Identity=25.2491694352159, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=162, Percent_Identity=31.4814814814815, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788748, Length=178, Percent_Identity=34.2696629213483, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=35.042735042735, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=269, Percent_Identity=26.0223048327138, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32551; Mature: 32551

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLNGIVAFVRAADALSFVAAGRTLGISASAVGKTIARLEQSLGVRLFNRTTRRITLTD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCEEEEEEC
EGRHFYERCQRILEDLRDAEATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDV
CCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCE
ELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPFAFVLCATPAYLARAGTPRAP
EEEECCCCCCHHHHHCCHHHHHHCCCCCHHHHHHHCCCHHEEHHHCCHHHHHHCCCCCCC
CDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGAVLAGLGIGYMP
CCCCHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCH
DFLARDALERGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFK
HHHHHHHHHCCCEEEEECCCEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNLNGIVAFVRAADALSFVAAGRTLGISASAVGKTIARLEQSLGVRLFNRTTRRITLTD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEECCCCEEEEEEC
EGRHFYERCQRILEDLRDAEATVTASAQRPRGKLRVSLPVIGYRFLLPVLPEFRQRYPDV
CCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCE
ELDLDFNDRMVDVVEGGFDAVIRSGPLSDSSLMSRRLGPFAFVLCATPAYLARAGTPRAP
EEEECCCCCCHHHHHCCHHHHHHCCCCCHHHHHHHCCCHHEEHHHCCHHHHHHCCCCCCC
CDLEAHDCVRYCFPTTGKLQDWALAADDGTPLKLRTAMTCNNMEALRGAVLAGLGIGYMP
CCCCHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCH
DFLARDALERGALVTVLDDYRIAPGQFSIVWPSSRQLSPKLRVFVDFLCERLFK
HHHHHHHHHCCCEEEEECCCEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]