| Definition | Burkholderia multivorans ATCC 17616 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010084 |
| Length | 3,448,466 |
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The map label for this gene is braG [H]
Identifier: 161523264
GI number: 161523264
Start: 89348
End: 90103
Strand: Direct
Name: braG [H]
Synonym: Bmul_0084
Alternate gene names: 161523264
Gene position: 89348-90103 (Clockwise)
Preceding gene: 161523263
Following gene: 161523265
Centisome position: 2.59
GC content: 66.4
Gene sequence:
>756_bases ATGAAGCACAGCGAACGGGAGGAACGCGAGTTGAGCGGTGTCGAAAGCGGCACGCCCGCGCTGGAAATCACGGGCCTCGA GGCCTGGTACGGGGAATCGCACATTCTGCATGGCGTCGATCTGACCGTGCATCGCGGCGAGGTCGTCACGCTGCTCGGCC GCAACGGCGCGGGCCGCACGACGACGCTGCGCGCGATCATGGGGCTCACGGGCCGCCGCAGCGGCTCGATCAAGGTGGCA GGCAACGAGACGATCGGTCTCGCGACGCACCGCATCGCGCATTTCGGTGTCGGCTATTGCCCGGAGGAGCGCGGGATCTT CTCGAGCCTGTCGTGCGAGGAGAACCTGATGCTGCCACCGATGATCGGCGCGCGCGAGAACGCGATGTCGCTCGACGACA TCTACGCGATGTTTCCGAACCTCGCCTCGCGGCGGCAGAGCCAGGGCACGCGGCTGTCCGGCGGCGAGCAGCAGATGCTC GCGGTTGCGCGCATCCTGCGCACGGGCGCGAACCTGCTGCTGCTCGACGAGATCTCGGAAGGCCTTGCACCGGTGATCGT GCAGGCGCTTGCGCGCATGATCGTCGCGCTGAAGTCGCGCGGCTACACGATCGTGATGGTCGAACAGAATTTCCGCTTTG CCGCACCGCTCGCCGACCGCTTCTACGTGATGGAGCACGGCCGCATCGTCGAACATTTCCGCGCGTCGGAACTGGAAGGC AAGATGCCGGTCCTGCACGACCTGCTCGGGGTGTGA
Upstream 100 bases:
>100_bases AGGTGCTCGCCGAGGGTTCGTATGCGGAGGTGTCGAAGAATCCGCTCGTCATCGAGGCTTACATGGGCAGCGCCGACGCG GCGCTCGCGGGGGCGCACGC
Downstream 100 bases:
>100_bases CGCCGCCCCGTTTCCTTGCCGCCGGCCGTCGCGGCGCACGAACAACCACAACGCATCAGAACAACAGGAGACGTCAATGA AAATGAAGACCCTCGCCCAC
Product: ABC transporter-like protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRTTTLRAIMGLTGRRSGSIKVA GNETIGLATHRIAHFGVGYCPEERGIFSSLSCEENLMLPPMIGARENAMSLDDIYAMFPNLASRRQSQGTRLSGGEQQML AVARILRTGANLLLLDEISEGLAPVIVQALARMIVALKSRGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRASELEG KMPVLHDLLGV
Sequences:
>Translated_251_residues MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRTTTLRAIMGLTGRRSGSIKVA GNETIGLATHRIAHFGVGYCPEERGIFSSLSCEENLMLPPMIGARENAMSLDDIYAMFPNLASRRQSQGTRLSGGEQQML AVARILRTGANLLLLDEISEGLAPVIVQALARMIVALKSRGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRASELEG KMPVLHDLLGV >Mature_251_residues MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRTTTLRAIMGLTGRRSGSIKVA GNETIGLATHRIAHFGVGYCPEERGIFSSLSCEENLMLPPMIGARENAMSLDDIYAMFPNLASRRQSQGTRLSGGEQQML AVARILRTGANLLLLDEISEGLAPVIVQALARMIVALKSRGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRASELEG KMPVLHDLLGV
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI31657092, Length=235, Percent_Identity=26.8085106382979, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI21536376, Length=200, Percent_Identity=28, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI45446740, Length=201, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI47078218, Length=201, Percent_Identity=29.8507462686567, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI27881501, Length=219, Percent_Identity=28.7671232876712, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI30795238, Length=219, Percent_Identity=28.7671232876712, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI105990541, Length=193, Percent_Identity=27.4611398963731, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI150417984, Length=223, Percent_Identity=26.9058295964126, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI27436953, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI116734710, Length=193, Percent_Identity=28.4974093264249, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4505771, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI9961250, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI9961252, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI153792144, Length=198, Percent_Identity=25.2525252525253, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI27477115, Length=220, Percent_Identity=27.7272727272727, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI27262624, Length=220, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI27262626, Length=220, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI87082268, Length=211, Percent_Identity=41.2322274881517, Blast_Score=150, Evalue=8e-38, Organism=Escherichia coli, GI1789593, Length=222, Percent_Identity=31.5315315315315, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=33.4782608695652, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1789672, Length=231, Percent_Identity=29.004329004329, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787792, Length=222, Percent_Identity=29.7297297297297, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1787029, Length=215, Percent_Identity=29.7674418604651, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1788450, Length=216, Percent_Identity=28.7037037037037, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1790190, Length=216, Percent_Identity=26.3888888888889, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1789864, Length=250, Percent_Identity=25.2, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1788897, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786253, Length=237, Percent_Identity=30.379746835443, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=31.0810810810811, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1787105, Length=248, Percent_Identity=27.4193548387097, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788761, Length=221, Percent_Identity=29.8642533936652, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1790525, Length=224, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI48995001, Length=216, Percent_Identity=26.3888888888889, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=29.8076923076923, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1786872, Length=222, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI87081791, Length=224, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786319, Length=229, Percent_Identity=28.3842794759825, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=26.9565217391304, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787712, Length=243, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1788644, Length=241, Percent_Identity=29.4605809128631, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=25.4716981132075, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87081782, Length=172, Percent_Identity=31.9767441860465, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=25.6880733944954, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=28.2407407407407, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI1788472, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789751, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786698, Length=173, Percent_Identity=26.5895953757225, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=27.1186440677966, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI87081709, Length=216, Percent_Identity=26.8518518518519, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1788210, Length=225, Percent_Identity=24.8888888888889, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1788165, Length=212, Percent_Identity=25.4716981132075, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789873, Length=212, Percent_Identity=22.6415094339623, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI87081834, Length=207, Percent_Identity=25.1207729468599, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI48994943, Length=241, Percent_Identity=23.2365145228216, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787112, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17510237, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=27.5555555555556, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=27.5555555555556, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI115533608, Length=230, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=27.5555555555556, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71983516, Length=196, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71983510, Length=196, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71983523, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI25146777, Length=206, Percent_Identity=26.6990291262136, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI212646699, Length=208, Percent_Identity=28.3653846153846, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565586, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6323959, Length=218, Percent_Identity=24.7706422018349, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI24648314, Length=213, Percent_Identity=27.2300469483568, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24666092, Length=212, Percent_Identity=27.8301886792453, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI116007328, Length=233, Percent_Identity=26.6094420600858, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI28574150, Length=233, Percent_Identity=26.6094420600858, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI221512771, Length=214, Percent_Identity=27.1028037383178, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643674, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI85725262, Length=187, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24650853, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24650855, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI281362751, Length=181, Percent_Identity=27.6243093922652, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 27477; Mature: 27477
Theoretical pI: Translated: 6.80; Mature: 6.80
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 4.4 %Met (Mature Protein) 5.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRT CCCCHHHHHHHCCCCCCCCEEEEECCHHHCCCCEEEECEEEEEECCCEEEEEECCCCCCH TTLRAIMGLTGRRSGSIKVAGNETIGLATHRIAHFGVGYCPEERGIFSSLSCEENLMLPP HHHHHHHHCCCCCCCCEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC MIGARENAMSLDDIYAMFPNLASRRQSQGTRLSGGEQQMLAVARILRTGANLLLLDEISE CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHC GLAPVIVQALARMIVALKSRGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRASELEG CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCHHHHEEEECCCHHHHHHHHHHCCC KMPVLHDLLGV CCHHHHHHHCC >Mature Secondary Structure MKHSEREERELSGVESGTPALEITGLEAWYGESHILHGVDLTVHRGEVVTLLGRNGAGRT CCCCHHHHHHHCCCCCCCCEEEEECCHHHCCCCEEEECEEEEEECCCEEEEEECCCCCCH TTLRAIMGLTGRRSGSIKVAGNETIGLATHRIAHFGVGYCPEERGIFSSLSCEENLMLPP HHHHHHHHCCCCCCCCEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC MIGARENAMSLDDIYAMFPNLASRRQSQGTRLSGGEQQMLAVARILRTGANLLLLDEISE CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHC GLAPVIVQALARMIVALKSRGYTIVMVEQNFRFAAPLADRFYVMEHGRIVEHFRASELEG CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEECCHHHHEEEECCCHHHHHHHHHHCCC KMPVLHDLLGV CCHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]